Dense polymeric blends with (transiently) fixed positive charges are ideal as anion exchange membranes (AEMs) for treating acidic wastewater with salts via diffusion dialysis. Pyrrolidone from vinylpyrrolidone (VP) copolymers offers a unique chemistry compared to conventional quaternary ammonium, enabling greener and more efficient membrane synthesis. The hydrophobic/hydrophilic characteristics and the miscibility of copolymers with membrane materials determine the microstructure and consequent membrane properties. Here, a commercial copolymer, poly(vinylpyrrolidone-co-vinyl acetate) (P(VP-VAc)), was blended with membrane material polyether sulfone (PES) to prepare PES-P(VP-VAc) blend membranes. The influence of VP content in the copolymers, casting solution composition, and membrane microstructure on the physicochemical properties, mass transfer performance, and stability of the membranes was systematically investigated. It was found that the copolymers (63.8-73.2 wt % VP content, similar to 80 kDa) were partially miscible with PES, resulting in microphase-separated membranes. With the VP mass fraction in the blend membranes increased, both the membrane mass increase and volume swelling degree in water and acid increased. When the membrane VP mass fraction reached 41.5 wt %, the permeability coefficients of sulfuric acid and ferrous sulfate increased rapidly. The PES-P(VP-VAc 6/4) blend membrane, containing 41.5 wt % VP, exhibited sulfuric acid and ferrous sulfate permeability coefficients of 228.5 and 4.1 x 10-9 m2/h, respectively. By simply blending two commercial polymers, this study successfully prepared PES-P(VP-VAc) blend AEMs with a microphase-separated structure, and their application in sulfuric acid recovery through diffusion dialysis was evaluated.

Oral ulcers severely affect the patient's mood, diet, and language activities and are mainly treated by topical administration of a patch. However, the currently commercially available patches have a limited treatment effect because of the short action time in the oral cavity. In this study, we present a novel adhesive patch made from trifunctional polycaprolactone crosslinked waterborne polyurethane (CDCPU) loaded with curcumin for treating oral ulcers. The long-chain triol cross-linking points in the polyurethane can limit water entry, while stabilizing the curcumin loading in the emulsion. Meanwhile, the interaction between curcumin and polyurethane improved the anti-swelling (swelling rate of 37.7 f 4.9 %), water resistance (water absorption rate of 66.6 f 5.6 %), and mechanical properties of the patch. The adhesion strength of the CDCPU patch to porcine oral mucosa and skin was 11.3 f 1.7 kPa and 14.7 f 2.5 kPa, respectively. The addition of curcumin provides the CDCPU patch with effective antibacterial and antioxidant functions. Moreover, the CDCPU patch was effective in promoting mucosal epithelialization and ulcer healing in a rat oral ulcer model. The development of this adhesive patch provides a new strategy for the treatment of oral ulcers.

Natural gas dehydration is essential for safe pipeline transport and corrosion prevention. Membrane separation technology has emerged as a compelling alternative, combining high operational efficiency, low energy demand, and environmental friendliness. This review delineates recent advances in membrane-based natural gas dehydration. First, we elucidate current insights into H2O/CH4 separation mechanisms. We then benchmark the dehydration performance of major membrane classes, including neat polymer membranes and hybrid membrane materials. Next, we appraise the respective merits and limitations of the single-stage versus multi-stage membrane dehydration processes. Industrial case studies are reviewed to illustrate the technology's practical viability and economic competitiveness. Finally, a sensitivity analysis interrogates the cost landscape of membrane systems in comparison with conventional triethylene-glycol absorption units. Collectively, the evidence marshalled herein delineates clear priorities for future inquiry: optimizing material design, improving pressure ratios, developing accurate models, and verifying industrial feasibility, all of which are pivotal to accelerating the deployment of membrane dehydration throughout the natural gas value chain.

Ketamine, an N-methyl-D-aspartate (NMDA) receptor antagonist, exhibits both therapeutic potential and abuse liability. However, the spatial distribution of ketamine across brain regions remains poorly characterized. Meanwhile, elucidating the mechanism underlying ketamine-induced psychiatric disorders through the investigation of metabolite alterations in the specific brain regions targeted by ketamine is of crucial significance. This study investigated the neurochemical effects of chronic ketamine administration in C57BL/6 mice using in situ mass spectrometry imaging (MSI) and metabolomics. Mice treated with ketamine (30 mg/kg daily for 15 days) exhibited increased anxiety-like behaviors without cognitive deficits. MSI revealed ketamine accumulation in the cerebral cortex, midbrain, and cerebellum, while the key neurotransmitter γ-aminobutyric acid (GABA) distribution shifted toward thalamic and striatum regions. The prefrontal cortex and cerebellum were selected as targeted brain regions for metabolomics analysis based on the MSI results. In metabolomics results, 73 and 134 differential metabolites in the prefrontal cortex and cerebellum were identified, respectively, predominantly linked to Alanine, aspartate, and glutamate metabolism, Estrogen signaling pathway, and GABAergic synapse pathways. This study integrated behavioral assessments, in situ MSI, and metabolomics to visually resolve and multidimensionally correlate ketamine's spatial distribution in the brain with region-specific metabolic changes in a ketamine-induced anxiety model. The findings reveal distinct neurochemical disruptions across brain regions and offer a groundwork for further elucidating the mechanisms of ketamine-related anxiety.

BACKGROUND:Artificial capnothorax during surgery potentially increases the risk of tumor cell dissemination and impacts survival. This trial aimed to investigate the effect of artificial capnothorax on the prognosis of patients with esophageal cancer who underwent minimally invasive esophagectomy. METHODS:This prospective, randomized controlled trial was conducted in two high-volume hospitals in China. Between August 2019 and January 2020, 110 patients with resectable esophageal cancer were randomized to undergo single-lung ventilation (n = 55) or capnothorax procedures (n = 55). The analysis was based on the intention-to-treat principle. The final follow-up occurred in January 2023. RESULTS:A total of 110 patients were included in the intention-to-treat analysis. After surgery, the incidence of patients exhibiting incremental changes in circulating tumor cell levels was 18.6% (8/43) in the capnothorax group and 2.7% (1/37) in the single-lung ventilation group (P = 0.033) (mean changes, -3.9 ± 3.4 [FU/3 mL] vs. -2.4 ± 2.9 [FU/3 mL], respectively; P = 0.039). Compared with the capnothorax group, the single-lung ventilation group had better 3-year overall survival rates (81.6%, 95% confidence interval [CI]: 72.4-92.0% vs. 65.2%, 95% CI: 59.3-78.8%; P = 0.049) and disease-free survival rates (81.6%, 95% CI: 72.4-93.0% vs. 61.6%, 95% CI: 50.1-75.7%; P = 0.019). Multivariate analysis indicated that artificial pneumothorax potentially impaired overall survival (hazard ratio [HR]: 2.35, 95% CI: 1.05-5.24; P = 0.037) and disease-free survival (HR: 2.70, 95% CI: 1.23-5.94; P = 0.014). CONCLUSIONS:Artificial capnothorax appears to be associated with poor oncological outcomes in patients with esophageal cancer. Single-lung ventilation in minimally invasive esophagectomy is safer and more favorable than capnothorax. TRIAL REGISTRATION:Chinese Clinical Trial Registry (http://chictr.org.cn), ChiCTR1900025262.

To address the limitations of sodium-ion battery (SIB) anodes, porous sulfur-doped carbon materials derived from petroleum coke (PC) were synthesized through a green, scalable approach involving low-temperature sulfidation and gradient carbonization. This approach enabled the simultaneous expansion of the interlayer spacing (d 002 = 0.373 nm for S-CY-850), and the construction of hierarchical pores (1-6 nm), achieved through thiophenic sulfur-induced lattice strain and in situ etching by CS2/SO2 evolution. The optimized S-CY-850 anode exhibited exceptional performance, including a high reversible capacity (420 mAh g-1 at 0.5 A g-1, representing a 5.38-fold improvement over undoped carbon), outstanding cycling stability (90.0% capacity retention after 2000 cycles), excellent rate capability (236.41 mAh g-1 at 5.0 A g-1), and an initial Coulombic efficiency (ICE) of 75.6%. This work presents a high-performance, low-cost anode solution for sodium-ion batteries (SIBs) derived from industrial byproducts, highlighting the synergistic effect of sulfur doping and microstructure modulation.

Postoperative adhesions, a prevalent complication following abdominal surgery, affect 90% of patients undergoing abdominal surgical procedures. Currently, the primary approach to prevent postoperative adhesions involves physical isolation of the surgical site and surrounding tissues using a hydrogel; however, this method represents a rudimentary strategy. Herein, considering the impact of oxidative stress and free radicals on postoperative adhesion during wound healing, an injectable antioxidant hydrogel, named PU-OHA-D, was successfully synthesized, which is formed by the crosslinking of dopamine-modified oxidized hyaluronic acid (OHA-D) and dihydrazide-terminated polyurethane (PU-ADH) through hydrazone bonding. PU-OHA-D hydrogel possesses versatile characteristics such as rapid gel formation, injectability, self-repair capability and biodegradability. Additionally, they exhibit an excellent ability to clear free radicals and superior tissue adhesion. PU-OHA-D can be injected in situ to form a hydrogel to prevent abdominal wall-cecum adhesion. Importantly, it can effectively eliminate free radicals and inhibit oxidative stress at the wound site. Thereby, it leads to collagen physiological degradation and prevents the occurrence of postoperative adhesions. The bioinspired hydrogel demonstrates its great potential in preventing postoperative adhesion and promoting wound healing.

Removing iron, aluminum, and magnesium ions from the primary wet-process phosphoric acid solution (WPA) is a promising strategy for mitigating scaling in downstream processing. Here, Donnan dialysis using Nafion membranes, with HNO3 as the stripping solution, was proposed and evaluated. The species in WPA as a function of temperature were modeled. The influence of HNO(3 )molarity (1-5 M), temperature (25-65(degrees) C), and Nafion membrane type on the metal ion mass transport was systematically studied. The effect of H(3)PO(4 )molarity on the metal ion mass transport was analyzed with synthetic WPA solutions, considering the form (free cation or complexed with anions) in which these metal ions transport through the membrane by analyzing the ionic composition of membranes in equilibrium with WPA. The coupled cation diffusion coefficients in membranes are modeled via the Nernst - Planck flux equation. It is found that the cation flux always follows this order: JMg > JAl > JFe for WPA. These factors can be attributed to: 1) in WPA Mg appears mostly as Mg2+, while almost all Fe ions and around half the Al ions are in a paired state, giving the bulky Fe(H2PO4)(2+), Al(SO4)(+ )and Al(SO4)Z, respectively; 2) only solution viscosity influences the Mg2+ transport, while both the solution viscosity and the complexation with anions influence Fe and Al transport; 3) Mg2+ ions have the largest diffusion coefficient in the membrane phase. These metal ions transport in the form of free cations through the membranes. It is concluded that Donnan dialysis is suitable for removing the fast-diffusing Mg2+ ions from diluted WPA, and increasing the solution temperature could enhance the Mg2+ transport rate.

This study introduces a novel technology for continuous vanadium precipitation, aiming to resolve issues such as poor stack density, small particle size, and irregular morphology of ammonium polyvanadate in traditional intermittent processes. In this research, we optimized the process parameters for continuous vanadium precipitation and investigated the mechanism of continuous ammonium polyvanadate crystallization using the focused beam reflectometer measurement. Results showed that small, flaky ammonium polyvanadate particles initially formed between 0 and 12 min. These particles subsequently interlayered and aggregated, resulting in larger particles from 13 to 23 min. By 24 to 60 min, a dynamic equilibrium was reached in crystal growth, aggregation, de-embedding, and fragmentation. Kinetic analyses demonstrated that increasing the reaction temperature shifted crystal growth from surface reaction control to diffusion control. At higher temperatures, explosive nucleation of ammonium polyvanadate, crystal fragmentation, and dissolution occurred. By integrating the crystallization mechanism, we produced dense ellipsoidal ammonium polyvanadate particles with a stacking density of 0.772 g/cm3 and an average size of 107.04 mu m under optimal conditions, achieving a vanadium precipitation rate exceeding 99.0%. Simulation results confirmed that the deflector tube baffle crystallizer enabled continuous crystallization of ammonium polyvanadate, ensuring an average residence time of over 10 min for particles of 50 and 100 mu m, facilitating their growth to at least 100 mu m. This research provides data and theoretical support for the industrial application of continuous vanadium precipitation.

The development of high-performance hard-carbon (HC) anode materials for sodium-ion batteries was constrained by slow charge-transfer kinetics and sodium-storage mechanisms. In this paper, high nitrogen-doped (12.24 %) HC with an efficient interworking structure was synthesized in situ using waste plastics as precursors by utilizing the strong 2-D self-template effect of guanine. Elucidating the mechanism of sodium storage in heteroatom-doped carbon with coexisting heterocyclic and graphitic nitrogen, which synergistically enhances electrochemical activity, utilizing a range of in-situ and ex-situ characterization methods. Based on density functional theory (DFT), it has been discovered that the doping of pyrrole nitrogen (N5) and pyridinium nitrogen (N6) can effectively expand the interlayer spacing during the Na+ sodiated/de-sodiated process, thereby enhancing electrochemical activity. The optimized HC has increased the Na+ diffusion coefficient by 1.5 orders of magnitude (10(-8.2) cm(2) s(-1) vs 10(-9.76) cm(2) s(-1)) and exhibits high reversible capacity (452 mAh/g@20 mA g(-1)), high rate performance (388mAh/g@500 mA g(-1)), superior cycling stability (87.6 % @500 mA g(-1) after 2,000 cycles). The full cell exhibits good cyclic stability (91.87 %@100 mA g(-1) after 2,00 cycles), while the designed pouch cell also demonstrates favorable cycle life (90.78 %@200 mA g(-1) after 100 cycles).

A solid reactive organophosphorus-nitrogen flame retardant 4N-BDP was devised and synthesized in order to address the flaws of the widely used organophosphorus flame retardants BDP as well as the issue of flame retardant modification of epoxy resin (EP). A series of flame-retardant EP composites were prepared by adding 4N-BDP and BDP to EP in a specific proportion. The flame-retardant properties of the two were compared, and the flame-retardant mechanism of 4N-BDP was deeply analyzed. The results of the UL-94 test revealed that sample 4N-BDP-6 obtained the greatest V-0 level, while BDP-6 had no level, when the addition ratio of flame retardant was 8.03%. In the cone calorimeter test, the peak smoke production rate (pSPR) and total smoke production (TSP) of BDP-6 were not significantly different from those of pure EP. In contrast, TSP and pSPR of 4N-BDP-6 decreased by 39.50% and 50.00% respectively compared with EP. Compared with BDP, 4N-BDP shows better flame retardancy and smoke suppression performance, which can significantly improve the fire resistance of EP. The flame-retardant mechanism of 4N-BDP was resolved by scanning electron microscopy, XPS, and thermogravimetric analysis/infrared spectrometry. 4N-BDP can increase the residual carbon rate of the composites, improve the residual carbon strength, play an excellent condensed phase flame retardant effect, and avoid further decomposition of the materials. In the gas phase, the decomposition of 4N-BDP produces PO center dot, PO2 center dot and NH3, which play a good quenching effect and dilution effect. The escape of NH3 will leave bubbles in the residual carbon, making the residual carbon more fluffy, further improving the ability of heat insulation and oxygen insulation, and enhancing the flame retardant effect of the condensed phase. In general, the flame-retardant mechanism of 4N-BDP is a synergistic combination of condensed phase and gas phase flame retardant mechanism. This work provides a new approach to improve the defects of organophosphorus flame retardant BDP commonly used in the market and enhance the fire resistance of EP.

Background: We aimed to construct and validate the esophageal squamous cell carcinoma (ESCC)-related m6A regulators by means of machine leaning.Methods: We used ESCC RNA-seq data of 66 pairs of ESCC from West China Hospital of Sichuan University and the transcriptome data extracted from The Cancer Genome Atlas (TCGA)-ESCA database to find out the ESCC-related m6A regulators, during which, two machine learning approaches: RF (Random Forest) and SVM (Support Vector Machine) were employed to construct the model of ESCC-related m6A regulators. Calibration curves, clinical decision curves, and clinical impact curves (CIC) were used to evaluate the predictive ability and best-effort ability of the model. Finally, western blot and immunohistochemistry staining were used to assess the expression of prognostic ESCC-related m6A regulators.Results: 2 m6A regulators (YTHDF1 and HNRNPC) were found to be significantly increased in ESCC tissues after screening out through RF machine learning methods from our RNA-seq data and TCGA-ESCA database, respectively, and overlapping the results of the two clusters. A prognostic signature, consisting of YTHDF1 and HNRNPC, was constructed based on our RNA-seq data and validated on TCGA-ESCA database, which can serve as an independent prognostic predictor. Experimental validation including the western and immunohistochemistry staining were further successfully confirmed the results of bioinformatics analysis.Conclusion: We constructed prognostic ESCC-related m6A regulators and validated the model in clinical ESCC cohort as well as in ESCC tissues, which provides reasonable evidence and valuable resources for prognostic stratification and the study of potential targets for ESCC.

Waste plastic with rich ester bonds, polyterephthalate (PET), is selected as the precursor to synthesize HC with different micromorphologies via low-temperature pyrolysis strategies. The relationship between the microstructure and sodium-ion storage behavior is evaluated.

Recycling graphite from spent lithium-ion batteries has been largely ignored. In the present work, we propose a novel purification process, which modifies the structure of graphite through phosphoric acid leaching-calcination to obtain high-performance phosphorus (P)-doped graphite (LG-temperature) and lithium phosphate products. The content analysis of X-ray photoelectron spectroscopy (XPS), X-ray fluorescence (XRF) and scanning electron microscope focused ion beam (SEM-FIB) indicates that the LG structure is deformed by the doped P atom. The results of In-situ fourier transform infrared spectroscopy (In-situ-FTIR), density functional theory (DFT) calcu-lation and XPS analysis show that the surface of the leached spent graphite contains rich oxygen groups, which react with phosphoric acid at high temperatures and form stable C-O-P and C-P bonds, making it easier to form stable solid electrolyte interface (SEI) layer. The increase of layer spacing is confirmed by X-ray diffraction (XRD), Raman and transmission electron microscope (TEM), which is conducive to the formation of efficient Li+ transport channels. What is more, Li/LG-800 cells possess high reversible specific capacities of 359, 345, 330 and 289 mA h g+1 at 0.2C, 0.5C, 1C and 2C, respectively. After 100 cycles at 0.5C, the specific capacity is as high as 366 mAh g+1, demonstrating the outstanding reversibility and cycle performance. This study proves and high-lights a promising recovery route for exhausted lithium-ion batteries anodes, making complete recycling possible.

Purification of wet-process phosphoric acid (WPA) is a crucial step in the preparation of high-purity phosphorus chemical products. The commonly used purification method in industry is solvent extraction. However, the high value utilization of raffinate has not been solved. In this study, a new process is proposed for tri-n-octylamine (TOA) extracting WPA without raffinate acid and preparing fine phosphates. TOA is an efficient solvent for extracting acid. But little research has been conducted on the application of TOA for WPA purification. The factors of affecting extraction efficiency of H3PO4 with TOA were investigated to obtain the conditions for efficient extraction. Especially, TOA concentration and initial phase ratio are the most significant factors. The theoretical stages of counter-current extraction were predicted by McCabe-Thiele analysis to achieve extraction rate of over 95%. The extraction complex (4TOA•3H3PO4•10H2O, TOA•H3PO4•3H2O, and TOA•2H3PO4•3H2O) and mechanism were confirmed according to the analysis of extractant composition, FT-IR and NMR spectrum characterization. Finally, 1.2 mol/L TOA extractant extracted H3PO4 from WPA after deep defluorination and four high purity fine phosphates were prepared. Overall, this study provides a novel process of preparing fine phosphate using WPA without raffinate. It is beneficial for mineral resources and environmental protection.

The removal of iron ions (Fe(Ⅲ)), aluminum ions (Al(Ⅲ)) and magnesium ions (Mg(II)) in phosphoric acid (H3PO4) solution is vital for recycle of spent electronic grade phosphoric acid, production of H3PO4 from wet-process and supply of phosphate fertilizer. Although phosphonic group (−PO3H2) functionalized resins exhibit excellent metal removal in wet-process phosphoric acid (WPA), the removal mechanisms aren’t clear yet. This work systematically studies removal of Fe(Ⅲ), Al(Ⅲ) and Mg(II) in WPA by using −PO3H2 functionalized resin MTS9500, including effects of solid-to-liquid ratio, Reynolds number, H3PO4 concentration and temperature. The removal mechanisms are determined from combined analysis of FT-IR, XPS, molecular dynamics (MD) and quantum mechanics (QM) simulations, which are based on density functional theory (DFT). Moreover, the intrinsic selectivity of Fe(Ⅲ), Al(Ⅲ) and Mg(II) on resin are quantified. The results show that removing mechanisms of Fe(Ⅲ) and Al(Ⅲ) are ion-exchange of H+ on −P3H2, while removal of Mg(II) is only adsorption mechanism. In addition, the metal-removal kinetics and isotherms are studied to further confirm removal mechanisms. At H3PO4 concentration of WPA production, the intrinsic selectivity coefficients (k) for Fe(Ⅲ)/Al(Ⅲ), Al(Ⅲ)/Mg(II) and Al(Ⅲ)/Mg(II) are 23.5, 30.3 and 1.29, respectively. This work replenishes sorption theory that can be used in recycle of electronic waste acid, sewage treatments, hydrometallurgy and purification of WPA.

In the context of sudden changes in global energy supply patterns, promoting the diversification of energy supply is an important movement for the sustainable development of the economy. Nuclear energy as a green and clean energy source has undergone rapid development. About 60 wt% of the world's fluorine production is used to produce uranium, a fuel for nuclear power plants. However, fluorine as a necessary raw material facing the challenges of high energy consumption and short lifespan of the electrolysis system. To overcome these drawbacks, this study aims to develop a high-efficiency electrolytic energy conversion system. Therefore, to optimize the design of the electrolysis system, the relationships between the electric field, the flow field and the electrode/electrolyzer geometry are simulated. Then, the simulation results are verified and further corrected by corrosion experiments. Subsequently, the key factors affecting the performance of the electrolyzer are obtained from the bubble separation experiment and simulation. Finally, a high-efficient electrolysis system is established and successfully put into industrial operation. In conclusion, in the course of model calculations, the method of reducing energy consumption is put forward, and the energy consumption is reduced from 17,000 to 14,980 kWh/ton by actual production, and the service life of carbon anode is extended from 90 days to 243 days. The breakthrough in fluorine electrolysis provides practical guidance for improving the performance of the electrolysis process.

Early diagnosis of esophageal squamous cell carcinoma (ESCC), a common malignant tumor with a low overall survival rate due to metastasis and recurrence, is critical for effective treatment and improved prognosis. Raman spectroscopy, an advanced detection technology for esophageal cancer, was developed to improve diagnosis sensitivity, specificity, and accuracy. This study proposed a novel, effective, and noninvasive Raman spectroscopy technique to differentiate and classify ESCC cell lines. Seven ESCC cell lines and tissues of an ESCC patient with staging of T3N1M0 and T3N2M0 at low and high differentiation levels were investigated through Raman spectroscopy. Raman spectral data analysis was performed with four machine learning algorithms, namely principal components analysis (PCA)- linear discriminant analysis (LDA), PCA-eXtreme gradient boosting (XGB), PCA- support vector machine (SVM), and PCA- (LDA, XGB, SVM)-stacked Gradient Boosting Machine (GBM). Four machine learning algorithms were able to classifiy ESCC cell subtypes from normal esophageal cells. The PCA-XGB model achieved an overall predictive accuracy of 85% for classifying ESCC and adjacent tissues. Moreover, an overall predictive accuracy of 90.3% was achieved in distinguishing low differentiation and high differentiation ESCC tissues with the same stage when PCA-LDA, XGM, and SVM models were combined. This study illustrated the Raman spectral traits of ESCC cell lines and esophageal tissues related to clinical pathological diagnosis. Future studies should investigate the role of Raman spectral features in ESCC pathogenesis.

BackgroundWith the advantage of the robotic suturing capacity, the purse-string suture is technically simple and convenient. This study aimed to present our technical aspects and initial results of robotic Ivor Lewis esophagectomy using two purse-string sutures for circular-stapled anastomosis.MethodsAfter stomach mobilization, gastric conduit formation, esophagus mobilization and two-field lymphadenectomy, the first robotic hand-sewn purse-string suture was applied to the esophageal muscular layer with an adequate margin above the tumor. A longitudinal incision in the anterior wall of the esophagus was made and the circular stapler anvil was inserted. The esophagus was transected by scissors 1 cm caudal to the first purse-string suture and the purse-string tied to secure the anvil. Then the second robotic hand-sewn purse-string suture was applied to the whole-layer of the proximal end of the esophagus and tied. Finally, the anvil was connected to the body of the stapler and fired.ResultsThe clinical data of ten patients who underwent robotic Ivor Lewis esophagectomy with an intrathoracic circular-stapled end-to-side anastomosis from February 2022 to April 2022 were collected. There were seven male and three female patients and had a mean age of 63.2 ± 7.6 years. Tissue donuts were complete in all cases and all operations were successfully performed without conversions. The mean overall operative time was 358.2 ± 40.3 min. The mean estimated blood loss was 83.2 ± 15.6 ml. The median length of hospital stay was 11.5 ± 4.1 days. All the patients had an uneventful postoperative period.ConclusionTwo purse-string sutures are necessary to obtain a tight seal of the esophageal tissue around the anvil to avoid potential anastomotic leak and are an essential process for the safety of circular-stapled anastomosis during robotic Ivor Lewis esophagectomy.

为实现对电气故障快速、准确和动态的分类,提出一种有机结合实例和属性加权的朴素贝叶斯电气故障分类方法(AIWNB);朴素贝叶斯分类方法中的先验概率和条件概率采用两种实例加权方式加以改进,积极实例权值取决于各属性值频度的统计值,而消极实例权值通过逐条计算训练实例与测试实例间的相关性加以确定;属性权值则基于互信息定义为属性-属性相关性和属性-类相关性之间的残差;所提出的AIWNB方法将属性加权和实例加权有机结合在朴素贝叶斯统一框架内,利用高低压用户的电气实测数据进行验证,实验结果表明,与朴素贝叶斯相比,加权后的朴素贝叶斯方法更具竞争性,准确率和F1分数可提升3.09％和9.39％,证明所提的AIWNB算法在电气故障分类的实用性及有效性;并与其他电气故障分类方法进行对比,验证算法的优越性.