Objective To investigate the adverse events occur after vaccination status in Harbin, discusses the influence factors of safety, the countermeasures to guarantee the safety of vaccination in Harbin. Methods Choose 2013 Harbin city vaccination of children as the research object, collects AEFI2013 years monitoring data of Harbin in January - December, analysis of Harbin city were reported adverse events occuring after vaccination, adverse reactions to the number of children, age composition, adverse reactions of vaccine, clinical manifestation, etc. Through interviews and field observation method to understand the main factors that ensure the safety of the vaccine immunization and vaccination safety countermeasures are put forward. Results By the centers for disease control and prevention in Harbin AEFI information management system, ac-cording to the results of AEFI2013 for 5083 cases, were given 1052894 doses of time, the incidence of adverse reactions was 0.48%. The 0 to 6 years old children vaccination dose of 735 216, 4 153 cases of adverse reaction, vaccination in chil-dren aged 7 to 14 317 678 times, 930 cases of adverse reaction, 0 to 6 years old children 0.56%incidence of adverse reac-tions after immunization and 7~14 years old children significantly higher than 0.29%(P< 0.05). Vaccination categories in-clude:HepB, BCG, PV, DPT, DT, MR, MMR, MM, MV, MenA, MenAC, JE l, JE - I, HepA -l, HepA - I. Rate of adverse reactions in which the DPT vaccine significantly higher compared with hemp MMR vaccine % %(P< 0.05). Children vac-cinated, for vaccination, without adverse reaction performance, common performance for nervous system abnormalities, aller-gic rashes, anaphylactic shock, blood vessels, nerve swelling and other symptoms. Conclusion The need to strengthen clini-cal adverse reactions after immunization monitoring, timely analysis summary vaccine safety influence factors, and take cor-responding measures to continuously reduce the incidence of adverse reactions.
卫生领域作为自然科学的重要方面,该领域科技期刊对于推动医学研究、临床试验、疾病预防控制、卫生管理的发展不可替代.文章分析了卫生领域科技期刊发展现状及存在问题,提出了对策建议.
目的:了解我院门、急诊抗菌药物不合理应用情况。方法:随机抽取我院2005~2006年门、急诊处方,根据临床药理学知识及文献资料,对不合理应用抗菌药物的处方进行分类、统计与分析。结果:共审核处方45203张,其中抗生素处方10752张,不合理用药处方1763张,分别在溶媒应用、给药方案、药理作用及合并用药等方面存在问题。结论:我院门、急诊抗菌药物应用情况基本合理,但仍存在问题,需进一步改善与提高。