Background: The NALLC trial (NCT01441752) demonstrated that postoperative adjuvant chemotherapy combined with traditional Chinese medicine (TCM) improved the quality of life (QoL) and survival in resected stage Ib-IIIa non-small-cell lung cancer (NSCLC) patients. This report updates disease-free survival (DFS) and other key outcomes.Methods: Between December 2012 and August 2015, 334 patients were randomized to receive either adjuvant chemotherapy plus traditional Chinese herbal granules (n = 167) or adjuvant chemotherapy plus placebo (n = 167) across 7 centers. Patients continued herbal granules or placebo daily until chemotherapy completion. DFS updates data was conducted in the intention-to-treat (ITT) population.Results: The median follow-up was 116.87 months. Median DFS was 71.83 months for the TCM group versus 43.60 months for the control (HR: .86; 95% CI: .64-1.15; P = .31). Two-year and 5-year DFS rates were 73.60% and 50.16% for TCM, compared to 67.45% and 44.08% for the control (P = .23). Median overall survival (mOS) was not reached in either group, with 75% OS at 63.40 months for TCM and 53.67 months for the control. Five-year OS rates were 76.15% for TCM and 69.81% for the control (P = .23). Subgroup analysis showed stage Ib patients benefited from TCM in both DFS (HR: .51; P = .02) and OS (HR: .34; P = .01).Conclusions: Adjuvant chemotherapy combined with TCM showed a potential trend toward improved DFS in early-stage NSCLC patients.Trial registration: This trial was registered with Clinical.Trials.gov (Number: NCT01441752, July 14, 2011).

Background Internal fixation for rib fractures has been widely carried out worldwide, and its surgical efficacy has been recognized. However, there is still controversy about whether implant materials need to be removed. At present, the research on this topic is still lacking at home and abroad. Therefore, in this study, the patients undergoing removal of internal fixation for rib fractures in our department within one year were followed up, to statistically analyze implant-related complications, postoperative complications and postoperative remission rate. Methods A retrospective analysis was conducted on 143 patients undergoing removal of internal fixation for rib fractures from 2020 to 2021 in our center. The implant-related complications, postoperative complications and postoperative remission rate of patients with internal fixation were analyzed. Results In this study, a total of 143 patients underwent removal of internal fixation, among which 73 suffered from preoperative implant-related complications (foreign-body sensation, pain, wound numbness, sense of tightness, screw slippage, chest tightness, implant rejection), and 70 had no post operative discomfort but asked for removal of internal fixation. The average interval between rib fixation and removal was 17 ± 9.00 (months), and the average number of removed materials was 5.29 ± 2.42. Postoperative complications included wound infection (n = 1) and pulmonary embolism (n = 1). of the 73 patients with preoperative implant-related complications, the mean postoperative remission rate was 82%. Among the 70 patients without preoperative discomfort, the proportion of discomforts after removal was 10%. No perioperative death occurred. Conclusion For patients with internal fixation for rib fractures, removal of internal fixation can be considered in the case of implant-related complications after surgery. The corresponding symptoms can be relieved after removal. The removal presents low complication rate, and high safety and reliability. For patients without obvious symptoms, it is safe to retain the internal fixation in the body. For the asymptomatic patients who ask for removal of internal fixation, the possible risk of complications should be fully informed before removal.

Background:Chest wall disease is a common disease in thoracic surgery. For most chest wall lesions, surgical resection is the mainstay of treatment. Reconstruction is indicated for a wide range of chest wall defects. Currently, various reconstruction materials are used in clinic, including 3D printing materials and various types of metal materials. At present, most of the studies using titanium sternum-rib fixation system for reconstruction are case reports. The purpose of this paper is to analyze the experience to discuss our essential surgical techniques for treating various types of chest wall reconstruction with a titanium sternum-rib fixation system over the last 5 years.Case Description:A retrospective analysis was performed on patients with chest wall tumors treated with a titanium sternum-rib fixation system in our center from 2016 to 2020. Chest wall reconstruction techniques, experiences, postoperative complications, and quality of life including chest discomfort, chronic pain, average time to return to normal life, chest wall deformity after resection for various types of chest wall tumors were analyzed. In this study, a total of 57 patients were successfully operated without chest wall deformity and return to daily life early. With an average of 2.3 ribs removed, including 10 procedures involving sternotomy and reconstruction and 3 procedures involving sternoclavicular joint resection and reconstruction. The follow-up time of the whole group ranged from 3 months to 5 years. Postoperative chest discomfort occurred in 6 patients during follow-up; 2 patients had chronic pain. The average time to return to normal life was 1.4 months. One patient developed a deformed depression of the chest wall, and 2 patients developed wound infections. There was no perioperative death.Conclusions:In our clinical experience, the titanium sternum-rib fixation system is safe, effective, and feasible. The technique is straightforward. The early and middle postoperative curative effect is satisfactory and can be used clinically.

Background This study aim to evaluate surgical procedures for titanium plate internal fixation of costal cartilage fractures with displacement or nonunion. Methods From January 2019 to October 2020, 13 patients with costal cartilage fractures were treated with titanium plate internal fixation in the thoracic surgery department of the Shanghai Sixth People’s Hospital. Pain severity scale scores and respiratory function were evaluated preoperatively and postoperatively. All the patients had a 6-month follow-up for treatment evaluation. Results The mean hospital length of stay was 10.7 days. A statistically significant difference ( P < 0.05) was found between preoperative and postoperative pain severity scores (7.69 vs. 5.00). VC (24.6% vs. 44.5%) and FEV1 (25.3% vs. 44.0%) were also significantly different before operation and after operation ( P < 0.05). At follow-up, healing of the nonunion or fracture was confirmed in all the cases. Conclusion The rigid titanium plate application ensured a safe and easy management of costal cartilage fractures and nonunion with a good prognosis as compared with other methods.

Background This study aimed to investigate the pulmonary ventilation function (PVF) according to different types of rib fractures and pain levels. Methods This was a retrospective study of patients with thoracic trauma admitted to our ward from May 1, 2015, to February 1, 2017. Vital capacity (VC), forced expiratory volume in 1 s (FEV1), and peak expiratory flow (PEF) were measured on admission. A numerical rating scale (NRS) was used for pain assessment. Results A total of 118 (85 males and 33 females) were included. The location of rib fractures did not affect the PVF. When the number of rib fractures was ≥5, the PVF was lower than in those with ≤4 fractures (VC: 0.40 vs. 0.47, P = 0.009; FEV1: 0.37 vs. 0.44, P = 0.012; PEF: 0.17 vs. 0.20, P = 0.031). There were no difference in PVF values between rib fractures with multiple locations and those with non-multiple locations (VC: 0.41 vs. 0.43, P = 0.202; FEV1: 0.37 vs. 0.39, P = 0.692; PEF: 0.18 vs. 0.18, P = 0.684). When there were ≥ 5 breakpoints, the PVF parameters were lower than those with ≤4 breakpoints (VC: 0.40 vs. 0.50, P = 0.030; FEV1: 0.37 vs. 0.45, P = 0.022; PEF: 0.18 vs. 0.20, P = 0.013). When the NRS ≥ 7, the PVF values were lower than for those with NRS ≤ 6 (VC: 0.41 vs. 0.50, P = 0.003; FEV1: 0.37 vs. 0.47, P = 0.040; PEF: 0.18 vs. 0.20, P = 0.027). Conclusions When the total number of fractured ribs is ≥5, there are ≥5 breakpoints, or NRS is ≥7, the VC, FEV1, and PEF are more affected. Trial registration The trial was conducted in accordance with the Declaration of Helsinki (as revised in 2013). The study was approved by the Ethics Committee of Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, and individual consent for this retrospectively registered analysis was waived.

目的:研究26S蛋白酶体ATP酶亚基2(proteasome 26S subunit ATPase 2,PSMC2)蛋白在非小细胞肺癌(non-small cell lung cancer,NSCLC)患者中的表达情况及其与NSCLC细胞患者预后的关系.方法:采用免疫组化方法分别检测58例NSCLC患者癌组织和癌旁组织中的PSMC2表达情况.从临床特征和病理特征两方面进行两组患者差异的比较.通过电话随访方式了解这58例患者手术后的生存状况,使用Kaplan-Meier法绘制生存曲线,比较两组患者的生存差异.Logistic回归分析PSMC2表达与临床病理参数的关系,同时使用COX回归进行单因素和多因素分析包括PSMC2在内的所有的临床病理特征与患者生存的关系.结果:一般临床资料比较发现,随着吸烟指数的升高,PSMC2阳性患者的人数与PSMC2阴性人数比值也随之增高.另外,在肿瘤最大直径和肿瘤分化程度上,PSMC2阴性患者与PSMC2阳性患者之间的差异有统计学意义(均P<0.05).Kaplan-Meier分析显示,PSMC2阴性患者的总生存期(62个月vs 56个月,P=0.004)和无进展生存期(48个月vs 45个月,P=0.043)均优于PSMC2阳性患者,差异有统计学意义.Logistic回归分析显示PSMC2表达仅与肿瘤分化程度有关(OR:3.511,CI:1.498～8.227,P=0.004).单因素分析表明PSMC2高表达(HR:2.950,CI:1.335～6.525,P=0.007)和肿瘤分化程度(HR:2.045;CI:1.210～3.461,P=0.008)与NSCLC患者的不良生存预后相关:而多因素检验分析进一步证明PSMC2阳性表达与NSCLC患者的不良结局相关(HR:3.165;CI:1.439～6.961,P=0.034).结论:PSMC2蛋白在NSCLC患者中有不同程度的表达,其表达的阳性程度与肺癌的恶性程度有一定关系,单因素和多因素分析均显示其阳性表达与患者的不良预后有关.

Background To evaluate therapeutic efficacy of minimally invasive and small incision surgery [minimally invasive surgery (MIS)] in patients with non-flail chest rib fractures through a prospective cohort study. Methods This study included 98 patients with non-flail chest rib fractures (≥3 displaced fractures) and 66 patients undergoing MIS served as the experimental group and 32 patients receiving conservative treatment served as the matched control group. Pain index and indicators of pulmonary function [vital capacity (VC); forced expiratory volume in one second (FEV1); peak expiratory flow (PEF)] for the two groups were assessed and compared at the time of admission and before discharge. In addition, duration of pain, time required for the patient to regain the ability to perform daily self-care, mental labor, and moderate-to-severe physical labor, and duration of chest discomfort were measured during long-term follow-up and compared between the two groups. Results There were also no significant differences (P>0.05) in pain index (8 vs. 8) or indicators of pulmonary function (VC: 31.0% vs. 26.5%; FEV1: 29.9% vs. 26.7%; PEF: 15.2% vs. 12.0%) were found between the MIS and conservative treatment groups at the time of admission; while pain index (3 vs. 6), VC (42.1% vs. 35.3%), and FEV1 (44.2% vs. 35.9%) were significantly different between the two groups (P<0.05) but not in PEF (21.2% vs. 19.6%) before discharge. Long-term follow-up showed that duration of pain, time required for the patient to regain the ability to engage in daily self-care, mental labor, and moderate-to-severe physical labor, and duration of chest discomfort in the MIS group were significantly more improved than in the conservative treatment group (P<0.05). Conclusions MIS was a simple and safe treatment that significantly relieved chest pain and rapidly restored pulmonary function and improved the long-term quality of life of patients with non-flail chest rib fractures of ≥3 ribs with displacement.

目的 探讨多发肋骨骨折患者手术治疗的最佳时机,以及合并其他部位骨折患者行同期联合手术的安全性和有效性.方法 回顾性分析2007年12月-2017年12月在上海交通大学附属第六人民医院行手术治疗的1 573例肋骨骨折患者的临床资料,筛选794例行单纯肋骨骨折手术的患者作为研究对象,根据伤后至手术的时间,分为＜3 d组(221例)、3～7 d组(337例)和＞7d组(236例),比较3组患者骨折断端平均固定时间、术后皮下负压引流时间和并发症情况.选择合并其他部位骨折行手术治疗的患者441例,分为同期联合手术组(同期手术组,316例)和分期手术组(125例),比较两组患者的治疗时间、麻醉费用和并发症情况.结果 在手术时机的研究中,3～7 d组的患者骨折断端平均固定时间显著短于＜3 d组和＞7 d组,＜3 d组显著短于＞7d组(P值均＜0.05).＜3 d组患者的术后皮下负压引流时间显著短于3～7 d组和＞7d组,3～7 d组显著短于＞7 d组(P值均＜0.05).3～7 d组患者的术后切口不良事件和肺部感染发生率均显著低于＜3d组和＞7d组(P值均＜0.05),＜3 d组与＞7 d组间的差异均无统计学意义(P值均＞0.05).在合并伤联合手术的研究中,分期手术组的住院时间、术后静脉镇痛药物使用时间均显著长于同期手术组(P值均＜0.05),麻醉费用显著高于同期手术组(P＜0.05).两组患者术后切口不良事件和肺部感染发生率的差异均无统计学意义(P值均＞0.05).结论 肋骨骨折手术时机的选择对患者的治疗和术后并发症的发生均有影响.伤后3～7 d是肋骨骨折手术的最佳时间.对于合并其他部位骨折的患者,同期联合手术可缩短治疗时间,减少多次麻醉带来的创伤和风险,并降低治疗费用,是经济、有效且安全的.

Rib fracture is the most common injury in chest trauma. Chest wall stabilization (CWS) has been employed in China for 10 years and has been recognized as a safe and practical technique for rib fracture therapy. A survey entitled "Surgical Treatment for Rib Fractures" was launched at the beginning of 2018 showing that 95.6% of the hospitals surveyed performed CWS in over 30,000 cases in the past 2 years. Despite the large volume of CWS performed in China, we discovered the following characteristics: lack of large-scale clinical research, and standardized recognition of surgical indications, high costs incurred for surgical consumables, and undefined professional standard. We revealed that most of the researches on CWS in China have room for improvement. The Shanghai Sixth People's Hospital has conducted a series of CWS researches in patients with multi-rib fractures whose results showed shorter therapeutic time, pain reduction, lower morbidity, and improvement in lung function. Consequently, we formulated our own surgical indications for CWS. Thoracoscopic-assisted minimally invasive CWS surgery had been conducted in several hospitals in China. Undoubtedly, the continuous improvement of equipment and surgical techniques will inevitably lead to its further development. Researches on materials with superior absorbability or tissue compatibility have been successfully conducted in China. However, the lack of multi-center and large-sample randomized controlled trials has been one of the key factors that hampered the accurate evaluation of CWS. Accordingly, a nationwide study entitled "Evaluation of the effectiveness of surgical fixation of multiple rib fractures-a multi-center and ambispective cohort study" was initiated in June 2018. It is believed that the result of this research would considerably improve and enrich the clinical evidence on CWS in rib fracture patients.

Objective To investigate the indications and surgical strategies for exploratory thoracotomy of chest stab wound. Methods We conducted a retrospective analysis of the clinical data of 80 patients who underwent thoracic exploration treatment for chest stab wounds from January 2006 to December 2017 in Shanghai Sixth People's Hospital. Results The 80 cases included 36 cases of stab wound only to chest , 16 combined with abdomen wound , 21 with limb wound, and 7 with neck wound.The average ISS score is 16.4. After emergency exploratory thoracotomy, 76 was cured (95%)and 4 died (5%). The reason for death was cardiac rupture, uncontrolled hemorrhagic shock, and disseminated intravascular coagulation (DIC). Conclusions Progressive hemopneumothorax, ventilation dysfunction, and cardiac tamponade are all important indications of emergency exploratory thoracotomy. Reasonable reactions to the surgical indications and suitable choice of operation pathway are the keys to cure chest stab wound. Key words: Chest; Stab wound; Thoracic exploration; Operation pathway

Objective To evaluate the effect of operative treatment of non-flail chest rib fractures. Methods A retrospective analysis of 109 patients who underwent non-flail chest rib fractures between May 2015 and June 2016 was conducted. We compared patients’ pain index and pulmonary function parameters (vital capacity, VC; forced vital capacity in the first second, FEV1; peak expiratory flow, PEF) at different stages: at hospital admission (IN), on the day before surgery (PRE), and on postoperative days one (D1), two (D2), and seven (D7). Results The 109 patients included 85 men (78.0%) and 24 women (22.0%) between the age of 23 and 74 ( with a mean of 52). 75 had multiple injuries (68.8%), 34 had chest trauma solely (31.2%), the average injury severity score (ISS) was 18.2.The average number of fractured ribs was 5.8 ( ranging from 3-16). The average length of time from admission to operative intervention was 4.4 days (ranging from 1-16). The fractures healed in all patients, while superficial wound infections occurred in two cases (1.8%), skin numbness around the incision occurred in 5 cases (4.6%). Pain and pulmonary function parameters (VC, FEV1, PEF) had improved significantly by postoperative day seven (P<0.05). Conclusions In patients with three or more non-flail chest rib fractures , early surgical treatment is safe, and can effectively relieve pain , leading to rapid recovery of lung function. Key words: Non-flail chest rib fractures; Operative treatment; Lung function; Pain index

Long non-coding RNAs (lncRNAs) have been reported to participate in the pathogenesis of non-small cell lung cancer (NSCLC). However, how lncRNA deleted in lymphocytic leukaemia 2 (DLEU2) contributes to NSCLC remains undocumented. The clinical significance of lncRNA DLEU2 and miR-30a-5p expression in NSCLC was analysed by using fluorescence in situ hybridization and TCGA cohorts. Gain- and loss-of-function experiments as well as a NSCLC tumour model were executed to determine the role of lncRNA DLEU2 in NSCLC. DLEU2-sponged miR-30a-5p was verified by luciferase reporter, and RIP assays. Herein, the expression of lncRNA DLEU2 was elevated in NSCLC tissues, and its high expression or low expression of miR-30a-5p acted as an independent prognostic factor of poor survival and tumour recurrence in NSCLC. Silencing of lncRNA DLEU2 repressed the tumorigenesis and invasive potential of NSCLC, whereas re-expression of lncRNA DLEU2 showed the opposite effects. Furthermore, lncRNA DLEU2 harboured a negative correlation with miR-30a-5p expression in NSCLC tissues and acted as a sponge of miR-30a-5p, which reversed the tumour-promoting effects of lncRNA DLEU2 by targeting putative homeodomain transcription factor 2 in NSCLC. Altogether, lncRNA DLEU2 promoted the tumorigenesis and invasion of NSCLC by sponging miR-30a-5p.

BACKGROUND:With the popularization of minimal invasive surgery, video-assisted thoracoscopic surgery (VATS) is gradually replacing conventional thoracotomy for lung cancer and is even used for osteosarcoma patients with pulmonary metastasis. In this study, we characterized the need for open surgery by comparing computer tomography (CT) diagnosis and postoperative pathology of patients with pulmonary metastases of osteosarcoma.METHODS:A retrospective analysis was carried out on patients with underwent surgery for pulmonary metastatic osteosarcoma admitted to our hospital between January 2008 and July 2018. The numbers of pulmonary metastatic nodules suspected by preoperative CT scan were calculated in addition to the number of nodules which were resected and pathologically confirmed to be metastatic during surgery. The Spearman correlation coefficient between the number of nodules on preoperative CT scan and the number of lesions pathologically confirmed was calculated.RESULTS:In total, 69 patients undergoing 96 thoracotomy operations were included in this study. The median interval between preoperative CT examination and operation was 7 days (range, 1-44 days). The median number of the suspected nodules on preoperative CT and the pathologically positive metastases resected during operation were 1 and 3, respectively. Remarkably, 36 (37.5%) thoracotomies revealed that more metastatic nodules were detected during thoracotomy than preoperative CT scans.CONCLUSIONS:Preoperative CT examination omits a few small pulmonary metastases of osteosarcoma and there is rare progress in recent years. Therefore, we recommend that patients with pulmonary metastases of undergo thoracotomy to locate and resect all metastases as much as possible through intraoperative direct palpation.

目的 急性肺损伤(acute lung injury,ALI)是指由肺炎、吸入损伤和创伤等因素导致的急性的、进行性的肺毛细血管内皮细胞和肺泡上皮细胞损伤,肺挫伤是其病程的早期阶段.而肺挫伤如治疗不及时患者往往进展为急性呼吸窘迫综合征(acute respiratory distress syndrome,ARDS),其死亡率高达30％～60％.但目前针对创伤性急性肺损伤仍然缺乏足够的研究.本文通过搜集近年来相关文献,对血清学标志物与创伤性急性肺损伤的发病关系进行综述,为其早期诊治及后续研究提供线索.

ObjectiveTo investigate the methods and clinical efficacy of reconstruction of chest defects with titanium sternal fixation system after the surgical resection of sternal tumors.MethodsA total of 6 patients with sternal tumor who were diagnosed and underwent resection and repair of the chest wall defects by titanium plates system, from 2017.3 to 2017.11 in our hospital were reviewed. Their pathological types, surgical reconstruction methods, follow-up results were analyzed.ResultsSix cases of sternal tumor were completely resected and the sternums were reconstructed with titanium sternal fixation system. There was no operative death, postoperative chest wall deformity, abnormal breathing or complications of respiratory circulation. After 3 to 10months of follow-up, there was no loose screw or plate exposure. Not only the thoracic appearances were good, but patients' satisfaction was high.ConclusionsSurgical resection is the best treatment for sternal tumors, no matter it is benign or malignant. Titanium sternal fixation system combine with other soft materials can reconstruct the chest wall well after resection, and this technique is efficient as well as easy to learn.

Objective To investigate the resection of chest wall tumor and the reconstruction of it.Methods Retrospectively summarize the diagnosis and treatment of 91 cases of chest wall tumors in our hospital from January 2008 to November 2017.There are 55 males and 36 females and the ages ranged from 7 to 78 years,with a median age of 43 years.82 cases were operated for the first time,and 9 cases were reoperated.The postoperative pathology showed that the benign were 52 cases and malignant were 39 cases.The largest benign tumor was 15 cm × 10 cm × 3 cm and the largest malignant tumor was 30 cm × 20 cm × 15 cm.Local excision was performed in 66 cases and extended resection in 25 cases.After the resection,ilium,titanium mesh,Dacron mesh and Matrix reconstruction system were selected for reconstruction of chest wall respectivly.Results All the operation was successful and without death.Local resection was performed in all of benign tumor and in 15 cases of malignant tumor,extended resection was performed in the other 24 malignant tumor cases.After the local resection,the soft tissue was sutured directly to reconstruct the chest wall.The enlarged resection of the bone was performed by reconstructing the bony chest with different materials.In the soft tissue reconstruction,1 cases were treated with myocutaneous flap,and the other 23 cases were sutured directly.Postoperative chest wall integrity is stable,no chest wall floating and abnormal breathing.1 patients received ventilator supportion,and 2 patients had wound infection.The chest wall defect caused by benign tumor has good quality of life,no recurrence.After resection of the malignant tumor of the chest wall,2 died,and the rest were still alive.Conclusion Local resection is the main therapeutic method of benign chest wall tumor,and malignant chest wall tumor is mostly enlarged excision.Bone remodeling after extended resection plays an important role in the reconstruction of chest wall.It is necessary to select appropriate materials for reconstruction.Matrix titanium sternal or rib reconstruction system fixed reliably and the follow-up in a short term were also satisfactory.

Studies have confirmed that, for severe flail chest or sternal fractures and even multiple rib fractures, surgical treatment can effectively reduce hospital stay and relieve chest wall pain. However, fixation of multiple costal cartilage fractures in such a small area is a challenge if an internal fixator is simply placed directly on the sternum. This case report shares a method of simultaneous fixation of multiple costal cartilage and sternal fractures through a small incision, and it is also appropriate for multiple costal cartilage fractures without sternal fracture.

This study aim to evaluate surgical procedures for titanium plate internal fixation of sternal fractures with displacement or nonunion.

肋骨骨折在胸部创伤中较为常见，占胸部创伤的55%[1]。其常见的致伤原因为交通伤、坠落伤、挤压伤、直接暴力伤等。连枷胸是较为严重的肋骨骨折类型，在胸部钝性伤中占10%~15%，病死率为16%~20%[2]。肋骨骨折的治疗可分为保守治疗和手术治疗。大多数肋骨骨折患者可以通过非手术治疗获得痊愈。本文对两种肋骨骨折治疗方法的优缺点以及手术内固定治疗的研究进展综述如下。

目的 探讨可吸收肋骨钉与记忆合金接骨板内固定两种方法治疗多发性肋骨骨折的效果.方法 回顾性分析2009年1月至2014年1月在上海市第六人民医院胸外科行手术内固定的胸部外伤致多根多处肋骨骨折患者321例的临床资料,其中可吸收肋骨钉组70例,其中男62例、女8例,年龄(48.54±9.74)岁;记忆合金接骨板组251例,其中男187例、女64例,年龄(51.44±10.22)岁.分析两组患者疗效差异.结果 两组患者术前疼痛评分(7.74±0.89 vs.7.66±0.92)、术后疼痛评分(3.80±0.79 vs.3.82±0.85),术后胸腔引流时间[(6.00±2.84)d vs.(5.68±2.98)d]差异均无统计学意义(P＞0.05).记忆合金接骨板组住院时间[(20.06±7.39)d vs.(17.77±7.68)d],及手术时间(101.29±30.67)min vs.(71.95±29.50) min]均短于可吸收肋骨钉组,且差异有统计学意义(P＜0.05).术后3个月随访复查胸部X线,两组患者骨折再移位差异无统计学意义.结论 可吸收肋骨钉与记忆合金接骨板均是治疗多发性肋骨骨折较理想的术式,记忆合金接骨板手术操作更为简单,可吸收肋骨钉手术无需在体内留置金属内固定装置,但固定强度较接骨板略差,应根据情况选择合适的内固定方法.