目的 观察益景汤联合康柏西普治疗气阴两虚夹瘀型非增殖性糖尿病性黄斑水肿(DME)的疗效.方法 采用随机数字表法将2021年2—10月就诊于福建中医药大学附属人民医院眼科60例(85眼)气阴两虚夹瘀型非增殖性DME患者分为对照组30例(42眼)及治疗组30例(43眼),对照组于入组后第1、31、61天玻璃体腔内注射2 mg/0.2 mL康柏西普0.05 mL,治疗组在对照组治疗基础上予以益景汤口服,每日1剂,疗程3个月.治疗结束时和治疗后30 d比较2组最佳矫正视力(BCVA)、黄斑中心凹视网膜厚度(CMT)、需要再次注射的眼数.结果 2组患眼CMT在治疗结束时和治疗后30 d均较治疗前降低(P均<0.05),BCVA均较治疗前提高(P均<0.05),与对照组比较,治疗结束时和治疗后30 d治疗组BCVA提高、CMT下降均更明显(P均<0.05);且治疗组需要再次注射的眼数较对照组减少(P均<0.05).结论 益景汤联合康柏西普治疗气阴两虚夹瘀型非增殖性DME能明显改善患者视力,有效消退水肿,恢复黄斑形态,从而减少治疗后再次注射次数,疗效较佳.

AIM:To observe the influence of wearing nocturnal orthokeratology lens on sleep quality in myopic patients.?METHODS: Totally 30 myopic patients ( 58 eyes ) wearing nocturnal orthokeratology lens, who received medical treatment at the Department of Ophthalmology of Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, were included in study ( treated group ) . And 30 myopic patients wearing spectacles at the same time were randomly selected as the control group. Sleep quality of two groups were assessed with Pittsburgh sleep quality index ( PSQI ) before and after wearing the lens in the first and the third months, and compared.?RESULTS:Equivalent diopter of the 30 patients wearing nocturnal orthokeratology lens was -2. 78D±0. 90D before treated with orthokeratology lens, -0. 30D ± 0. 31D after 1mo of treatment, and -0. 28D ± 0. 30D after 3mo of treatment. There was significant difference between the equivalent diopter got before treated with orthokeratology lens and that got after 1mo of treatment (P<0.05), and between the equivalent diopter got before treated with orthokeratology lens and that got after 3mo of treatment (P<0. 05). The total scores of PSQI of 30 myopic patients got before wearing nocturnal orthokeratology lens and after 1 or 3mo of that were respectively 2. 13±1. 36, 2. 47±1. 98, and 1. 74±1. 39. There only was significant difference in scores of subjective sleep quality got after 3mo of treatment between treated group and control group (P<0. 05), but no significant difference in scores of total PSQI, sleep latency, sleep duration, habitual sleep efficiency, sleep disturbances, use of sleeping medication, and daytime dysfunction( P>0. 05).?CONCLUSION:Wearing nocturnal orthokeratology lens has no significant effect on the overall sleep quality index of myopic patients, but the subjective sleep quality decreased in the early stage of wearing the lens.

目的:探讨采用术前评分的方法选择翼状胬肉病例作为研究生眼科显微技术培养的安全性和可行性.方法:根据年龄、病变分期、类型(初发或复发)、长度及宽度等因素对翼状胬肉患者进行术前评分.将总分为5～7分的翼状胬肉患者58例(61眼)随机分成A、B组,行翼状胬肉切除联合球结膜转位术,A组30例(32眼)由有良好临床显微手术经验的住院医师和上级医师共同完成,B组28例(29眼)由规培研究生和A组的同一上级医师共同完成.术后随访6～12个月,观察比较两组患者的手术时间、角膜创面愈合时间、复发率、手术并发症的差异.结果:A、B两组患者的手术时间分别为(25.16 +2.89) min、(33.38±3.62) min,A组短于B组(Z=-6.324,P=0.000).A、B两组患者角膜创面愈合时间分别为(5.16±1.32)d、(5.28±1.49)d,两组比较差异无统计学意义(Z=-0.339,P=0.735).A组有2眼复发,复发率为6.25％;B组有2眼复发,复发率为6.90％,两组复发率比较差异无统计学意义(x2=0.010,P=0.919).结论:从个体化出发,采用术前评分的方法选择适合的研究生参与翼状胬肉病例的手术,可以达到良好的手术效果,复发率低,未见明显手术并发症.

2014年5月-2015年9月我们用补阳还五汤加减合康柏西普治疗气虚血瘀型视网膜静脉阻塞黄斑水肿14例,疗效较好,现报道如下. 1 临床资料 1.1纳入标准①视力下降或视物变形者;②眼底检查见受累静脉区内视网膜表层出血,视网膜水肿及棉绒斑,阻塞的静脉扩张、纡曲者;③荧光血管造影见视网膜受累静脉充盈时间延迟,血管壁渗漏,毛细血管扩张、迂曲,未见大片毛细血管无灌注区及新生血管,黄斑区弥漫性渗漏者;④光学相干断层扫描显示黄斑中心区视网膜厚度增加,中心凹变浅或消失者;⑤符合视网膜静脉阻塞气虚血瘀型的中医辨证分型诊断标准者.

目的观察丹栀逍遥散与桃红四物汤合激光光凝治疗视网膜静脉阻塞的疗效。方法将61例61只眼随机分为治疗组30例,用丹栀逍遥与桃红四物汤合激光光凝治疗;对照组31例用激光光凝治疗。结果总有效率治疗组为90%,对照组为83.9%。结论丹栀逍遥散与桃红四物汤合激光光凝治疗视网膜静脉阻塞,具有促进视网膜出血、渗出的吸收,提高视力,缩短病程,减少视细胞损害的功能。

驻景丸是中医眼科临床常用之传统名方,具有滋补肝肾之效,常用于肝肾亏虚之眼病的治疗.为了继承发扬的需要,笔者通过查阅相关古籍并检索《中华医典》[1](该光盘收录历代中医古籍约1000余种),对该丸及加减方等进行考据,撰文如下.