Objective:To explore the efficacy of Wuling Capsules in the treatment of insomnia patients. Methods:The clinical data of 72 patients with insomnia diagnosed and treated in our hospital from January 2021 to December 2021 were retrospectively analyzed，and they were divided into an observation group and a control group according to different treatment methods，with 36 cases in each group. Among them，the control group was given estazolam tablets，and the observation group was given Wuling capsules，both groups were treated continuously for 4 weeks. The sleep conditions，clinical efficacy and adverse reactions were compared between the two groups.Results:After treatment，the sleep status self-rating scale (SRSS) score of the observation group was lower than that of the control group，and the difference was statistically significant (P<0.05). The incidence of reaction (5.56%) was lower than that of the control group (22.22%)，and the difference was statistically significant (P<0.05). Conclusion:The application of Wuling Capsules in the treatment of patients with insomnia can obtain exact curative effect，can effectively improve their sleep quality，and has high safety.

目的 探讨急性脑梗死溶栓治疗的临床疗效,并归纳总结溶栓治疗的临床研究进展.方法 53例急性脑梗死患者,随机分为观察组(27例)和对照组(26例).两组患者均采用静脉溶栓治疗,对照组患者静脉给药尿激酶,观察组患者则采用溶栓新药阿替普酶.比较两组患者神经功能评分、治疗效果及不良反应发生情况.结果 观察组患者的治疗前和治疗后2 h、1 d、1周、1个月的神经功能评分分别为(28.6±7.6)、(18.3±11.4)、(16.7±12.4)、(12.6±9.5)、(12.7±7.8)分,对照组各时间点神经功能评分分别为(26.7±8.2)、(24.6±10.8)、(23.5±9.4)、(21.5±6.8)、(17.3±8.6)分;治疗前两组神经功能评分比较差异无统计学意义(P>0.05),两组治疗后各时间点的评分比较差异具有统计学意义(P<0.05).观察组患者经溶栓治疗后总有效率92.59%显著高于对照组的69.23%,对比差异具有统计学意义(χ2=4.722,P<0.05).观察组患者的不良反应的总发生率为11.11%,显著低于对照组的46.15%,差异具有统计学意义(χ2=8.016,P<0.05).结论 溶栓治疗方式针对急性脑梗死疾病疗效显著,临床上加强了对溶栓药物的相关研究,该治疗方式的临床应用前景广阔.

Objective:To investigate lesion patterns on DWI and stroke mechanism in acute progressive cerebral infarction inmiddle cerebral artery area,and its MRA angiostenosis performance.Methods:The MCA area progressive cerebral infarction patients 112 examples for the progress group,the MCA area complete cerebral infarction patients at the same time 130 examples were a complete group.Studies two group of patients lesion patterns and the correlation angiostenosis situation.On acute stage DWI the lesion patterns divides into 4 kinds:territor infarcts,subcortical infarcts,border-zone infarcts,and several disseminated small infarcts.Results:The incidence ratio of border-zone infarcts was greater in the progress group than in the complete group(60.7% vs 13.1%;P<0.05),by MCA severe stenosis primarily(49.1% vs 20.8%;P<0.05),and also easy to appear many angiostenosis;the incidence ratio of territor infarcts was greater in the complete group than in the progress group(56.2% vs 8.9%;P<0.05),by MCA occlusion primarily(38.4% vs 8.9%;P<0.05).Conclusion:Border zone infarcts are more seen in MCA severe stenosis and many angiostenosis in MCA area progressive cerebral infarction,the brain irrigation insufficient is possibly its primary cause.

目的:观察喜炎平注射液治疗急性上呼吸道感染的疗效。方法:采用随机分组方法,将186例急性上呼吸道感染患者分为治疗组100例,对照组86例,对照组以青霉素钠与病毒唑治疗,治疗组在对照组基础上加用喜炎平注射液。2组进行临床疗效比较。结果:治疗组治愈率、总有效率均高于对照组,经统计学分析差异有显著性(P<0.01)。结论:喜炎平注射液治疗急性上呼吸道感染效果好,副作用低。