Objective To explore the effects of cinobufagin capsule on coagulation status,therapeutic effect and quality of life of patients with advanced lung cancer.Methods A total of 64 patients with advanced lung cancer admitted to the Second People＇s Hospital of Jinzhong from February 2017 to January 2018 were selected,and they were divided into control group and observation group by random number table method,with 32 cases in each group.The control group was treated with chemotherapy, and the observation group was treated with cinobufagin capsules combined with chemotherapy.Blood coagulation status,quality of life score,pain numerical rating scale ( NRS) and functional status score( KPS) were observed before and after treatment in the two groups.The clinical efficacy was compared between the two groups. Results Before treatment, there were no statistically significant differences in plasma fibrinogen(FIB),platelet(PLT),D-dimer,quality of life score,NRS score and KPS score between the two groups(all P>0.05).After treatment,the FIB,PLI and D-dimers in the observation group were (3.6 ± 0.9)g/L, (248.3 ± 11.3) ×109/L,(19.8 ± 1.2) mg/L respectively,which were significantly lower than those in the control group [(4.5 ± 0.6)g/L,(398.2 ± 16.2) ×109/L,(40.2 ± 0.6) mg/L] (t=11.642,21.045,18.249,all P＜0.05).The total effective rate of the observation group was 90.6%(29/32),which was significantly higher than 68.8%(22/32) of the control group ( χ2 =6.903,P ＜0.05). The quality of life scores of the two groups were improved,and the life scores of the observation group were significantly higher than those of the control group( t=11.642,21.045,18.249,17.218,all P＜0.05).The NRS score of the observation group (3.62 ± 1.53) points was significantly lower than that of the control group[(5.01 ± 2.34)points],and the KPS score of the observation group [(78.25 ± 3.81) points] was significantly higher than that of the control group [( 72. 34 ± 4. 12 ) points], the differences were statistically significant (t =16.082,15.082,all P ＜0.05). Conclusion Treatment of advanced lung cancer with cinobufagin capsule combined with chemotherapy can significantly improve the coagulation state, treatment effect and quality of life of patients.

目前,随着医学科学技术的发展,对恶性肿瘤的明确诊断上并不困难,但在治疗上则属世界难题,特别是高龄肿瘤患者、非手术适应证,又不接受当今的化、放疗治疗的患者.本课题就是应用蟾蜍攻坚复合剂对肿瘤患者的治疗进行临床研究,通过对门诊、住院病例进行分组观察对照,从而对蟾蜍攻坚复合剂在治疗恶性肿瘤的疗效进行评价.

足跟痛是中老年人的一种常见病,其表现为站立或行走时,足跟及足底有酸胀疼痛感,严重时呈针刺样痛,难以举步.引起足跟痛的主要原因是体胖、劳累、寒湿或外伤、骨刺等,导致足跟软组织损伤和跟骨退行性病变,或继发无菌性炎症.治疗老年足跟痛可选用下列简便有效的方法.

小儿细菌性痢疾是夏、秋季常发病,多见于2岁～7岁儿童,主要临床症状为发热、腹痛、腹泻、脓血便,严重者可致水电解质紊乱、惊厥、休克,如治疗不当,可危及生命.近3个月来,笔者采用中西药结合疗法治疗本病9例,疗效满意,现报道如下.

腰椎间盘突出症为一常见病,多发于青壮年,属于中医学"腰痛"、"痹证"范围.随着CT、MRI技术的广泛应用,该病确诊率大大提高.我科于2000年～2004年间采用骶疗和腰椎牵引在腰突症治疗上取得了很好疗效,现总结如下.

消痛合剂是笔者的自拟方,从1988年以来,外用内服收到了良好的治疗效果,现介绍如下,供同道参考.

笔者根据近年临床实践研制了"通痹膏"用以治疗痹症,取得了比较满意的效果,现报道如下.

笔者应用七枝风湿膏治疗风湿痹痛100例,并进行对照观察,取得了较满意的效果,现报告如下.