Objective To explore the clinical application value of dynamic electrocardiogram (ECG) in diagnosis of Kawasaki disease ( KD) combined with coronary artery lesions .Methods Totally 160 cases of KD treated in Zhejiang Xiaoshan Hospital during January 2012 to August 2014 were selected as research subjects , including 80 cases without coronary artery lesions in control group and 80 cases combined with coronary artery lesions in observation group .In the observation group 80 cases were randomly divided into dynamic ECG group and routine ECG group with 40 cases in each group according to number table methods .All patients were given dynamic ECG and routine ECG examination .The dynamic ECG detection results were compared between the observation group and the control group as well as the dynamic ECG group and routine ECG group in the observation group .Results The incidence rate of atrioventricular block , average heart increasing and total abnormal frequency in the observation group were significantly higher than those in the control group , and the differences were statistically significant (χ2 value was 5.0171, 8.3502 and 9.6274,respectively, all P <0.05).The proportion of atrioventricular block in the dynamic ECG group was 20.00%, which was significantly higher than 2.50%of the conventional ECG group with statistical significance (χ2 =4.1530,P<0.05).The proportion of patients with sustained tachycardia in the dynamic ECG group was 27.50%, and it was significantly higher than 0.00%of the conventional ECG group with significant difference (χ2 =8.8657,P<0.05). In the dynamic ECG group proportion of cases with abnormal results was 52.50%, and it was obviously higher than 10.00% in the conventional ECG group (χ2 =10.0253,P<0.05).Conclusion Dynamic ECG is obviously superior to conventional ECG in diagnostic of KD combined with coronary artery lesions , so it can be used as a routine detection means of KD , which is worthy of clinical promotion .

Objective To study the clinical efficacy and safety of esophageal pacing in termination of old patients with paroxysmal supraventricular tachycardia heartbeat.Methods A total of 68 elderly cases with paroxysmal supraventricular tachycardia heartbeat were given the esophageal pacing termination of therapy,who were treated with overdrive suppression method and a burst termination,and the clinical curative effect and adverse reaction in the two groups were observed.Results 34 cases were given overdrive suppression method,19 cases were successful,the success rate was 55.9％,the direct restoration of sinus rhythm includes 14 cases after the termination,accounting for 73.6％,heartbeat bradycardia occurred in 3 cases after termination,heart rate less than 50 beats per minute,and then disappeared.With a burst of 34 cases,31 cases were successful,the success rate was 91.2％,the direct restoration of sinus rhythm includes 25 cases after the termination,accounting for 80.6％,heartbeat bradycardia occurred in 4 cases after termination,heart rate less than 50 beats per minute,and then disappeared.Conclusion Esophageal pacing is an electrophysiological examination and treatment method with noninvasive,safe and effective advantages,the termination of PSVT has higher success rate,and it can distinguish between different types of PSVT.Compared with overdrive suppression method,burst terminate PSVT pulse method has higher success rate,it is worthy application in clinical.

目的研究急性心肌梗死（AMI）患者体表心电图 T 波峰末间期（Tp －Te）与急性期室性心律失常的关系。方法将143例急性心肌梗死患者依据是否发生室性心律失常分为 A 组（室性心律失常组，共89例）和 B 组（无室性心律失常组，共64例），分析它们的临床资料，尤其是分析心电图的 T 波峰－末间期（Tp －Te）、经心率校正的波峰－末间期（Tp －Tec）、波峰－末间期离散度（Tp －Ted）。结果心肌梗死急性期，A 组患者 Tp －Te、Tp －Tec、Tp －Ted 均较 B 组延长，比较均差异有统计学意义（P 均＜0．05）。经 Person 分析，显示 Tp －Te、Tp －Tec、Tp －Ted 与室性心律失常的发生均呈正相关，P 均＜0．05，相关系数 r 分别为：0．645、0．714、0．685。结论心电图 T 波峰末间期延长与急性心肌梗死急性期室性心律失常关系密切，呈正相关，可尝试作为预示发生室性心律失常的一个指标。

目的评价抗菌药物干预前后骨科Ⅰ类切口手术围术期的预防用药情况。方法随机选取2011年1～3月骨科Ⅰ类切口手术出院患者200例作为干预前组,另选取2012年1-3月患者200例作为干预后组,比较2组抗菌药物使用率、使用时间≤24h者比例及平均用药时间。结果干预后组抗菌药物使用率低于干预前组,抗菌药物预防使用时间≤24h者比例高于干预前组,用药时间短于干预前组,差异均有统计学意义(P<0.05)。结论通过干预,可显著提高骨科围术期的抗菌药物用药水平,降低药物费用,对促进临床安全、有效、经济地应用抗菌药物具有良好效果。

目的研究门诊药房服务特点和优化措施。方法应用运筹学和数据统计方法,对门诊药房服务特点进行定量研究,开展科学化、效率化、个体化服务。结果科学化优化了流程,提高了门诊药房的运行效率;个体化提高了患者满意度。结论门诊药房科学化、效率化、个体化服务有效可行,可提高服务质量。

目的探讨完全性左束支传导阻滞合并左室肥厚的心电图情况。方法采用回顾性分析的方法,分析我院完全性左束支传导阻滞患者80例心电图资料,依据是否合并左室肥厚分为单纯完全性左束支传导阻滞组50例和完全性左束支传导阻滞合并左室肥厚组30例。结果完全性左束支传导阻滞合并左室肥厚组Sv2、Sv3、Sv3+Rv6均高于单纯完全性左束支传导阻滞组,P<0.05,差异均有统计学意义。结论 Sv2、Sv3、Sv3+Rv6均可以作为诊断完全性左束支传导阻滞合并左室肥厚诊断方式,值得临床推广应用。

介绍了免疫脂质体的分类,主要分为抗体介导型免疫脂质体和受体介导型免疫脂质体;作用特点主要有靶向性、缓释型和细胞亲和性;并介绍了抗体与脂质体的主要连接方法;实际应用主要为作为抗肿瘤药物的载体、基因治疗的载体以及治疗中枢神经系统疾病的药物载体。

目的:对急性心肌梗死合并完全性左束支传导阻滞的各种心电图表现进行分析和讨论.方法:观察15例急性心肌梗死合并完全性左束支传导阻滞的心电图表现.结果:急性心肌梗死合并完全性左束支传导阻滞的心电图表现多样.结论:胸痛患者如果合并左束支传导阻滞时,要高度警惕AMI,详细询问病史,观查ECG动态演变,随时监测心肌坏死标志物CTnI,避免因漏诊和误诊耽误时间而延误治疗.

中药汤剂的煎煮质量直接关系到药物疗效,由于煎煮机器的局限性、从业人员素质等因素大大影响了煎煮质量,所以细化煎药操作规程很重要,有必要具体到特殊入药的每一味中药。

探讨对精神分裂症患者稳定期开展药学服务的方法,药学服务可以增强患者用药依从性,极大限度发挥药物的疗效,减少精神分裂症患者的复发次数。帮助患者提高生活质量。

对我院精神科门诊2006年3月1日至2006年3月31日所有门诊病人处方5130张,统计病人年龄,使用镇静药物名称、规格、用量、用药时间、使用频率。结果:镇静催眠药物药物使用率50.39%。其中单用一种镇静催眠药物药物占78.84%。二种药物合用20.83%。临床使用以苯二氮卓艹类新型催眠药物为主。