A型塞内卡病毒(SVA)是一种单股正链RNA病毒,属于微RNA病毒科(Picornaviridae)塞内卡病毒属(Senecavirus).SVA作为猪水疱病的一种新病原体,在多个国家传播和发展迅速,引发猪不同程度的水疱性疾病,尤其以巴西、中国以及越南等多个国家病情较为严重,给当地养猪业造成重大的经济损失.该病原导致的临床症状与口蹄疫相似,且不同性别和年龄阶段的猪均易感,可引起感染猪的鼻吻、蹄冠部出现水疱性病变,仔猪急性死亡.因此,需要对SVA的流行和发病引起足够的重视,并通过一系列快速检测方法进行监测以防止该病毒的传播.本文对目前A型塞内卡病毒检测的技术和方法进行了综述,并对其应用情况以及各自的优、缺点进行了分析和总结,以期为A型塞内卡病毒检测方法的深入研究提供参考.

Objective To discuss the applicationeffect of formative assessment in the orthopaedics training during surgery resident standardized training. Methods A total of 40 residents who attended the Department of Orthopaedics during surgery resident standardized training in Clinical College of Yangzhou University from 2016 were selected as subjects and randomly divided into experimental group and control group, with 20 in each group. The formative assessment was used in the experimental group and summative evaluation was used in the control group. During and after the orthopaedics training, training effect was evaluated by examination and questionnaire survey. Results After the training, the students in the experimental group achieved significantly higher scores in the mid-term assessment and admission examination than thos before the training, and the examination scores of experimental group were higher than those of control group, the differences were statistically significant (P<0.05). In addition, the formative assessment scores of the students in the experimental group were positively correlated with the mid-term assessment results and the entrance examination results (r=0.931, r=0.886; P<0.05). The clinical decision-making ability, self-learning ability, attitude and professional self-score and the total score were also higher than those of control group, the differences were statistically significant (P<0.05). Conclusion Formative assessment used in orthopaedics training during surgery resident standardized training is beneficial to improve training effect and the quality of teaching.

目的:通过对七子白进行皮肤用药毒性试验,探讨七子白的皮肤用药安全性,为临床研究提供理论依据.方法:均采用白色Wistar大鼠,(1)皮肤急性毒性试验将30只大鼠随机分为5组,每组6只,分别为空白组、七子白完整皮肤高、低剂量组、七子白破损皮肤高、低剂量组,给药一次,观察7天.(2)皮肤刺激试验将30只大鼠随机分为5组,每组6只;分别空白组、七子白完整皮肤和破损皮肤组、阳性药物完整皮肤和破损皮肤组,单次刺激,多次刺激连续给药7天.(3)皮肤过敏试验将18只大鼠随机分为3组,每组6只,分别空白组、七子白组、阳性药物组.结果:皮肤急性毒性试验结果中大鼠未发现毒性反应;单次刺激及多次刺激结果显示,七子白对完整和破损皮肤无刺激性,刺激反应评分为0.过敏试验中,阳性药物的致敏率为100％,七子白的致敏率为0.结论:七子白无明显副作用,是一个安全有效的皮肤美白外用方.

随着研究的不断深入,人们对心身疾病的认识也愈来愈深刻.从其概念的日趋准确到机制的不断完善再到相关治疗方法的推陈出新,充分说明心身疾病已得到了广大医学工作者的高度重视.