目的 探讨分析核苷类似物与干扰素对慢性乙肝的治疗效果.方法 选取慢性乙肝患者120例,随机分为观察组与对照组各60例,在两组当中应用不同治疗方法,随后探究其治疗效果.结果 观察组乙肝病毒脱氧核糖核酸转阴率为86.6%,对照组为56.3%(P<0.05)结论 核苷类似物与干扰素对慢性乙肝的治疗效果最佳,具有研究价值.

Objective:To explore the curative effect and safety of tenofovir,lamivudine,efavirenz combined scheme and zidovudine+lamivudine+efavirenz scheme in the treatment of HIV infection patients.Methods:115 patients with HIV infection were selected.They were randomly divided into two groups.1 group was given tenofovir+lamivudine+efavirenz treatment.2 group was given zidovudine+lamivudine+efavirenz treatment.The HIV RNA level and CD4 cell count improvement of the two groups were studied.Results:In the HIV RNA level and CD4 cell count improvement of the two groups,the difference was not statistically significant.The two groups all had adverse reactions.Conclusion:The curative effect and safety of tenofovir,lamivudine,efavirenz combined scheme and zidovudine+lamivudine+efavirenz scheme in the treatment of HIV infection patients have no statistical difference.The medication convenience,adverse reaction tolerance of the tenofovir group are better than those of the zidovudine group.

结核性脑膜炎（TBM）是最严重的肺外结核病，病死率为20%～30%[1]，目前治疗结核性脑膜炎主要是抗结核、降颅压、对症支持及腰穿鞘内注药治疗，我们于2009年6月至2012年6月选取结脑患者32例，其中16例采用鞘内置管连续给药治疗，取得了满意疗效。现报告如下。

<正>糖尿病与肺结核均属于多发病、常见病,两者可同时并存,相互影响,近几年来肺结核疾病有上升趋势。在糖尿病合并肺结核时,肺结核疾病往往发展迅速,血糖愈高,病情愈重,较好的控制血糖,对肺结核的转归极为重要。我院将2005年～2007年收治的58例合并糖尿病的初治菌阳肺结核患者在抗痨治疗的基础上分别使用口服降糖药物与胰岛素的临

Objective To examine the epidemic tendency and the correlated factors related to such tendency about fungal infection in respiratory tract of pulmonary tuberculosis patients.Methods One thousand eight hundreds and thirty-nine hospitalized patients with Pulmonary tuberculosis were sampled retrospectively for the study.The patients were classified into subgroups based on their age,sex,and methods if treament.Prevalence and incidence rates and cause of disease were analyzed accordingly.The data were processed by statistical methods.Results Out of the 1839 patients,27 examples were identified as infected with fungus in the airway and infection rate is 1.47%.The difference of infective rates between man(1.51%) and woman(1.37%) was not significant (P0.05);but the difference of infective rates between the patients above 60-year-old(2.82%) and the patients under 60-year-old(0.05%) was significant (P0.05) and so was the difference between infective rates between the patient's antibiotic efficiency rates and the rates uniting with medicine(P0.05). Conclusion The fungus infectine incidence rates in respiratory tract of pulmonary tuberculosis patients is related to the age and the wide use of antibiotics for a long time,it is not associated with the sex.

结核性胸膜炎是一种临床常见病、多发病,通常采用抗结核治疗,配合反复胸腔穿刺抽液及胸腔内注入或不注药治疗方法[1],胸腔内注药一般多采用异烟肼+地塞米松.白细胞介素-2是一种白细胞代谢产物,常用于肿瘤治疗,因其可以提高病人细胞免疫功能增强抗感染力,对肺结核也有一定的治疗作用,为探讨白细胞介素-2在结核性胸膜炎治疗中的作用,我们对诊断为结核性胸膜炎的患者采用抽液后注射异烟肼+地塞米松+白细胞介素-2的治疗效果报道如下.

Objective:To investigate the efficacy and safety of BFS intervention therapy for MDR-PTB.Methods:67 cases of drug resistant pulmonary tuberculosis were randomly divided into two groups:experiment group and control group.The experiment group was administrated with massive dose of drugs including isoniazid 0.2,amikacin 0.2,para-anionosalicylic and Sodium Chloride in dose of 10ml through bronchofibroscope combined with general chemotherapy.The controls received general chemotherapy.Results:Compared with control group,the rate of negative sputum bacteria,the rate of absorbed lesion and the rate of closed calvity increased at every month and the sixth months(P<0.05,P<0.05,P<0.01).Conclusion:The medication by bronchofibroscope combined with general chemotherapy were effective in treatment of drug resistant pulmonary tubeculosis,its effect is superior to general therapy.There are no serious complications and toxic and adverse reaction occurred

目的探讨肺炎衣原体(CP)与支气管哮喘的相关性.方法选择哮喘发作期和缓解期各31例,健康对照组30例,采用金标斑点法检测血清CP抗体,金标斑点法测定血清IgM、IgG,聚合酶链反应检测痰中CP-DNA.结果哮喘发作期CP感染率35.5%明显高于哮喘缓解期和对照组(P＜0.05.哮喘发作期和缓解期CP感染率分别为35.5%、6.4%,高于对照组(P＜0.05),同时IgM在哮喘发作期(27.3%),IgG在哮喘缓解期(36.4%).CP-PCR-DNA测定哮喘发作期,缓解期IgM组分别为22.6%、9.7%、对照组3.3%.结论CP感染为哮喘急性加重的一个重要诱因,而且是哮喘反复发作的原因之一.

目的研究胸腔积液EB病毒基因(EBVG)在良、恶性胸液中的鉴别诊断,并与结核基因(TBG)进行对比.方法用聚合酶链反应(PCR)检测胸腔积液EBVG与TBG.结果68例患者:(1)结胸组38例:EBVG 9例(23.7%),TBG29例(76.3%),(2)恶胸组30例:EBVG 24例(80%),TBG 6例(20%).基因检测的灵敏度为0.89,特异度0.90,正确率0.91.结论胸腔积液EBVG检测,可作为一种诊断恶性胸腔积液的辅助手段.

我院以普鲁卡因与酚妥拉明两药联用治疗肺结核大咯血28例,并选用同期普鲁卡因治疗26例为对照,收效显著,现报告如下: 对象和方法 1.病例选择:1997年1月至2000年12月,我院收治合并肺心病的肺结核大咯血病例中,以24小时咯血＞500ml,或一次咯血200ml以上为大咯血诊断标准,并符合全国肺心病诊断标准.普鲁卡因皮试阴性者共54例,按入院顺序随机分为治疗组与对照组,治疗组28例,男18例,女10例,年龄50～79岁,平均年龄为63.5岁,浸润型12例,慢纤洞16例.对照组26例,男14例,女12例,年龄52～76岁,平均年龄61岁,浸润型9例,慢纤洞17例.