Objective:the clinical ef ect of corneal edema of dif erent regimens for the treatment of smal incision cataract surgery.Methods:from 2012 September to 2013 were selected from Department of ophthalmology in our hospital in November 174 cases of smal incision cataract surgery in patients with corneal edema,and divided into routine group and combination group according to the random number method,87 patients in each group.The conventional group treated with recombinant bovine basic fibroblast growth factor eye drops,compound tropicamide eye drops and tobramycin and dexamethasone eye drops in treatment.Joint group on the treatment based on the given Huoxue Lishui granule in the treatment group,two in a week for a course of treatment,continuous treatment of two courses.Results:Clinical combined treatment group total ef ectiveness 95.4%,cure time is 3 -11 days,average 4.5 days,is superior to the conventional group 65.5%,3 -15 days,so it has statistical significance (P <0.05)standard.Conclusion:combining traditional Chinese and Western medicine treatment of corneal edema after smal inci-sion cataract surgery is accurate,it is worthy of popularization and application.

由于眼睑皮肤较薄，颜面部烧伤后眼睑皮肤烧伤的深度往往较其周围皮肤严重，甚至遗留睑外翻畸形，表现为睑结膜向外翻出，使眼裂，可发生炎症、溢泪、干燥、增生或慢性溃疡［1］。因此，睑外翻畸形需要及时、有效的治疗。2006年以来，我们针对颜面部烧伤所造成的单纯下睑外翻，根据下睑皮肤的解剖特点在瘢痕松解后以不均一厚度的皮片游离移植进行矫正，取得了较好的治疗效果。

OBJECTIVE To study the correlation between optic disc parameters measured by Cirrus SD-OCT and visual field detect in early primary open-angle glaucoma (POAG). METHODS The tomography of optic nerve head was measured by Cirrus SD-OCT in 55 patients (55 eyes) with early POAG and 55 normal subjects 55 eyes. 3D cube OCT data was obtained using Opitic Disk Cube 200×200 Scan pattern, which performed raster scanning in a 6×6mm square centered on the opitic head composed of 200A-scans and 200B-scans. Disc area, rim area, average cup/disc ratio, vertical cup/disc ratio, and cup volume were evaluated. These ONH parameters were compared be-tween normal subjects and eyes with early POAG. All eyes were detected by Synemed EP-930 perimetry. The corre-lation between mean deviation and optic disc parameters in early POAG eyes was also analyzed. SPSS 17.0 statistical software was used for statistical analyses. RESULTS There were significant differences of all optic disc parameters between normal and early POAG eyes except disc area (P<0.001). Rim area had marked correlation with MD in ear-ly POAG eyes (r=0.562, P<0.001). CONCLUSIONS Measurement of optic disc parameters by Cirrus HD-OCT was useful in detecting early glaucomatous damage and had marked correlation with MD.

目的 评估谱域光学相干断层扫描仪Cirrus HD-OCT测量正常人视盘旁视网膜神经纤维层(RNFL)厚度的可重复性.方法 同一位操作者应用Cirrus HD-OCT对45人(53只眼)正常人视盘采用200×200的视盘扫描模式进行重复测量,测量全周平均、上、下、鼻、颞象限及12个钟点位RNFL厚度值,应用SPSS 17.0统计学软件计算组内相关系数(intraclass correlation coefficient,ICC)和变异系数(coefficient of variation,CV)来评估Cirrus HD-OCT测视盘旁RNFL厚度的可重复性.结果 全周RNFL厚度的ICC和CV值范围分别为0.851～0.993,1.6％～5.7％.其中上方象限的ICC值最高为0.991;平均RNFL的ICC值为0.986,颞侧ICC值为0.983,下方ICC值为0.982,鼻侧象限的ICC值最低为0.937,即上方＞平均＞颞侧＞下方＞鼻侧.全周平均厚度的CV最低为1.6％,3钟点位的CV最高为5.7％.与其相对应的12个钟点位中,11点、12点和1点的ICC值分别为0.975、0.986、0.963,2点、3点、4点的ICC值分别为0.941、0.851、0.910,5点、6点、7点的ICC值分别为0.931、0.962、0.978,8点、9点、10点的ICC值分别为0.968、0.927、0.964.结论 Cirrus HD-OCT测量正常人视盘RNFL的可重复性较高,在青光眼早期诊断及监测其早期进展方面具有较大的临床应用价值.

Objective To explore the clinical manifestations of comprehensive extraocular muscle paralysis patient, carries on the analysis of causes and prognosis. Method The clinical manifestation of 135 cases of extraocular muscle paralysis patients, the ocular position, eye movement, diplopia test, CT, MRI, DSA imaging examination, biochemical test, neostigmine test to determine the cause, and the patients were followed up for 2 years, analyzed of the prognosis of the patients. Result The main clinical manifestations of extraocular muscle paralysis were diplopia (74.81%), dizziness (63.70%), nausea (54.07%), fever (49.63%), eye position deviation (35.56%) and strabismus, ptosis (25.93%), ocular movement disorder (20.74%), blood glucose (17.78%);etiology in diabetes (17.78%), traumatic brain injury (15.56%), cerebrovascular disease (12.59%), inflammation (10.37%), myasthenia gravis (9.63%); after two years of follow-up, 21 patients (22.96%) recurrence. Conclusion The clinical symptoms of muscle paralysis of eye are complex and the etiology is variety, it has good prognosis.

目的:探讨P53蛋白与P21蛋白在翼状胬肉中的表达.方法:应用免疫组化法检测30例翼状胬肉和正常结膜中P53蛋白与P21蛋白的表达.结果:30例翼状胬肉中P53蛋白和P21蛋白的阳性表达平均秩次分别为45.12和15.50;30例正常结膜中P53蛋白和P21蛋白的阳性表达平均秩次分别为15.88和45.50.P53蛋白与P21蛋白阳性表达在翼状胬肉中与正常结膜两组间差异有统计学意义(P<0.01).结论:P53蛋白与P21蛋白在翼状胬肉及正常结膜中均有阳性表达,且P53蛋白在翼状胬肉中高表达,P21蛋白在翼状胬肉中低表达,说明翼状胬肉是一种组织增殖性疾病.

目的:观察改良翼状胬肉手术的临床疗效.方法:对翼状胬肉患者21 2例,行翼状胬肉切除转移术,复发胬肉加0.02％丝裂霉素术后观察3个月1.5年.结果:治疗组1 06例中没有一例复发,角膜光滑,术后散光小,外观好,无并发症,治愈率100％;对照组:106例,复发1 6例,角膜不光滑,术后散光大,治愈率达85％,两者比较差异有统计学意义(P＜0.05).结论:改良翼状胬肉手术治疗效果肯定.

<正>翼状胬肉是由于各种原因导致角膜、Bowman膜及角膜浅层基质蛋白质的损害和变性,从而引起原发增厚而导致角膜缘隆起,形成翼状胬肉。它是眼部结膜受外界刺激而引起的一种慢性炎症,其发病机理尚未完全清楚。翼状胬肉是眼科较为常见的眼表疾病之一。它可以引起角膜散光从而影响视力,严重

目的探讨血管刺激生长因子(VEGF)和抑癌基因P53在翼状胬肉中的表达。方法应用免疫组化法检测30例翼状胬肉组织(病例组)和30例正常结膜(正常组)中VEGF、P53的表达。结果 2组VEGF免疫组化评分(IHS)数值比较差异有统计学意义(P<0.05)。2组P53IHS数值比较差异有统计学意义(P<0.05)。病例组VEGF和P53比较:2组的差异有统计学意义(P<0.05),二者的IHS值差异有统计学意义(P<0.05)。结论 VEGF和P53均在翼状胬肉中异常表达,且均为高表达,提示翼状胬肉组织血管活性增强,增殖活性增强,可能与翼状胬肉的发生、发展和术后复发有关,选择性的VEGF和P53拮抗药物可以有效减少翼状胬肉的发生,为临床药物研究提供理论支持。

翼状胬肉的治疗以手术为主,可是单纯翼状胬肉切除术的复发率高达24%～30%常使术者深感棘手.笔者近10年来,采取术中、术后多环节阻止胬肉复发,疗效比较明显.报告如下.

<正>硬脑膜海绵窦A-V瘘是神经外科熟悉的一种颅内动静脉直接交通。有些患者以不明原因的眼红而就诊于眼科,由于眼科医生对此患者不熟悉而导致误诊。现将本院3例误诊病例报告如下。

院自制1%硝酸银眼用制剂,经临床应用很满意,现报告如下. (1)作用和用途:本品与蛋白质及氯化物可发生沉淀而形成蛋白银及氯化银,逐渐变为黑色的金属银,其能放出微量的银离子而有抑菌作用.

近年来,荧光素及吲哚青绿眼底血管造影在Ⅱ型糖尿病视网膜病变诊断中的应用.其中包括将荧光素及吲哚青绿血管造影用于早期诊断非增殖期、增殖前期、增殖期糖尿病视网膜病变及糖尿病黄斑病变的诊断与分型等.毫无疑问,应用荧光素及吲哚青绿眼底血管造影技术能更透彻理解糖尿病视网膜病变,并能增加其诊断的准确率.