目的:观察腹腔镜精索静脉高位结扎术对精索静脉曲张(VC)患者术后康复及精液质量的影响.方法:选取2015年7月至2017年11月收治的98例VC患者的临床资料进行回顾性分析,其中49例行开放式精索静脉高位结扎术(对照组),49例行腹腔镜精索静脉高位结扎术(观察组).比较两组手术时间、住院时间、并发症发生率、精子浓度、a+b级精子比率及正常形态精子比率.结果:观察组住院时间明显短于对照组,差异有统计学意义(P<0.05);术后3个月,两组精子浓度、a+b级精子比率、正常形态精子比率较术前均明显提高,差异有统计学意义(P<0.05),但两组组间比较,差异无统计学意义(P>0.05);观察组并发症发生率为2.04％,明显低于对照组的18.37％,差异有统计学意义(P<0.05).结论:腹腔镜精索静脉高位结扎术治疗精索静脉曲张能在改善患者精液质量的前提下,缩短手术时间,降低并发症发生率.

目的 探讨萆薢分清饮联合盐酸左氧氟沙星胶囊治疗慢性前列腺炎患者的临床疗效.方法 将106例慢性前列腺炎患者按随机数字表法分为两组,每组53例,均予以口服盐酸左氧氟沙星胶囊治疗,在此基础上实验组联合革薢分清饮治疗,观察6周.治疗前后采用美国国立卫生研究院慢性前列腺炎症状指数评定两组症状严重程度,检测两组白细胞计数变化,记录两组平均尿流率、最大尿道闭合压、最大尿流率变化,检测前列腺液白细胞介素-10、肿瘤坏死因子-α、单核细胞趋化因子水平,比较两组临床疗效.结果 治疗后实验组美国国立卫生研究院慢性前列腺炎症状指数生活质量、排尿、疼痛各维度评分均显著低于对照组(P＜0.01);尿动力学指标平均尿流率、最大尿流率水平较治疗前显著升高,且显著高于对照组(P＜0.01),最大尿道闭合压水平较治疗前显著下降,且显著低于对照组(P＜0.01);前列腺液白细胞介素-10、肿瘤坏死因子-α、单核细胞趋化因子水平及白细胞计数均显著低于对照组(P＜0.05或0.01);实验组总有效率(94.3％)显著高于对照组(73.6％)(P＜0.01).结论 萆薢分清饮联合盐酸左氧氟沙星胶囊治疗慢性前列腺炎患者具有协同增效作用,临床疗效显著,可减轻炎性反应,缓解临床症状,改善尿动力学指标,提高生活质量.

目的 探讨经尿道前列腺双极等离子电切术(PKRP)治疗良性前列腺增生(BPH)患者的近期随访结果.方法 选取2015年10月～2017年10月本院75例BPH患者,根据手术方案分为对照组(n=37)和实验组(n=38).对照组给予经尿道前列腺电切术(TURP),实验组给予PKRP.观察两组手术时间、腺体组织重量、住院时间、并发症,术后随访3个月膀胱最大容尿量(VMCC)、最大逼尿肌压力(MDP)、残余尿量(PVR)、最大尿流量(Qmax)及勃起功能障碍发生情况.结果 实验组住院时间、手术时间短于对照组,差异有统计学意义(P＜0.05),实验组腺体组织重量与对照组比较,无显著差异(P＞ 0.05);实验组尿失禁、电切综合征、尿道狭窄等并发症发生率较对照组低(P＜0.05);两组均无脱落病例.术前、术后3个月两组PVR、MDP、VMCC、Qmax水平比较,无显著差异(P＞0.05);两组均无脱落病例.术后3个月实验组勃起功能障碍发生率低于对照组,差异有统计学意义(P＜0.05).结论 BPH患者采用PKRP治疗,可减少并发症,缩短手术时间及住院时间,且对尿动力学指标及勃起功能影响较小.

目的：分析腹腔镜下微波消融辅助治疗小肾癌的临床治疗效果。方法回顾性分析应用腹腔镜下微波消融辅助治疗的20例小肾癌患者的临床资料,肿瘤≤3 cm 的患者直接行微波消融,肿瘤>3 cm 的患者在肿瘤周围行微波消融,再行切除术,观察患者的临床治疗效果。结果20例患者经过手术治疗后,均获取成功,所有患者肿瘤边缘病理检查均未发现瘤细胞,患者的平均手术时间(101.5±14.3)min、平均术中出血量(70.6±2.38)ml、平均住院时间(5.7±1.3)d,20例患者有3例出现并发症,其中1例发热、2例出血,经过对症治疗后均缓解,并发症的发生率为15%。治疗后,患者的血红蛋白、肌酐变化不大,治疗前后比较,差异无统计学意义(P>0.05)。结论腹腔镜下微波消融辅助治疗小肾癌治疗效果好,手术时间短,术中出血量少,平均住院时间短,对血红蛋白和肌酐等相关指标影响不大,具有临床应用价值。

目的 研究糖尿病大鼠骨质疏松发病过程中骨桥蛋白的表达.方法 24只雄性Wistar大鼠随机分成2组,糖尿病大鼠组12只,空白对照组12只,饲养4月后处死动物,检查骨桥蛋白mRNA水平表达.结果 糖尿病组骨桥蛋白总RNA提取及RT-PCR、琼脂糖凝胶电泳显示,糖尿病组大鼠在骨质疏松发病过程中,骨桥蛋白在骨组织中高表达,与空白对照组相比,差异具有显著性.结论 骨桥蛋白在糖尿病大鼠骨组织有显著性改变,推测骨桥蛋白参与调节骨质疏松发病过程.

Objective:To evaluate the efficacy of high-frequency hyperthermia combined with indomethacin for treating patients with chronic abacterial prostatitis/pelvic pain syndrome(CPPS).Method:Three hunder and twenty-one cases of chronic abacterial prostatitis/PPS were treated by high-frequency hyperthermia with indomethacin and the curative effect of this method was evaluated.Result:After 1 month treatment,163 patients were cured(50.78%),an obvious effect was achieved in 112 cases(34.89%),27 cases(8.41%) were considered effective,19 patients(5.91%) were considered non-effective.Conclusion:High-frequency hyperthermia combined with indomethacin are clinically effective therapy and safety for patients with chronic abacterial prostatitis/PPS.

We investigated the plant regeneration and production of flavonoids in three high-yield flavonoids transgenic Saussurea involucrata hairy roots C17, C27 and C46 by quantification of two phytohormones GA3 and IAA. The results showed that GA3 concentration at more than 1.0 mg/L could induce adventitious shoots in the hairy root lines. The highest shoot regeneration rate, about 82%, was obtained when the hairy roots C17 were cultured with 2.0 mg/L GA3. The results on HPLC and UV spectrophotometry showed that exogenous application of both GA3 and IAA increased the content of flavonoids in the hairy roots. The contents of flavonoids and apigenin in the hormone-treated hairy roots and regenerates were higher comparing with those in the untreated hairy roots and the regenerates. However, the content of flavonoids was not related to tissue weight, and was negatively related to the regeneration efficiency.

OBJECTIVE: To observe the clinical efficacy of Sanjin tablets in the treatment of chronic prostatitis.METHODS: A total of 150 patients were randomly assigned to receive Sanjin tablets(treatment group) or Sanjin tablets plus levofloxacin capsules(control group) for 4 weeks.RESULTS: In the treatment group,NIH chronic prostatitis symptom index(NIH-CPSI) decreased from 18.22±7.23 before treatment to 5.23±3.12 after treatment,and the effective rate in this group was 83.33%;in the control group,NIH-CPSI decreased from 18.34±5.15 before treatment to 11.26±5.32,and the effective rate in this group was 68.33 %.There was significant difference between the two groups in curative effect(P0.05).CONCLUSION: Sanjin tablet is effective in the treatment of chronic protatitis.

目的:研究中西医结合治疗前列腺痛临床疗效。方法:治疗组口服中药及盐酸坦索罗辛0.2mg/d,对照组仅口服盐酸坦索罗辛0.2mg/d,观察两组治疗效果。结果:治疗组疗效优于对照组。结论:中西医结合治疗前列腺痛有良好效果。

目的:评价单用坦索罗辛(商品名:哈乐)治疗BPH的临床疗效。方法:将200例BPH患者随机分为坦索罗辛组、坦索罗辛+翁沥通组及坦索罗辛+保列治组,比较治疗后患者前列腺体积、IPSS症状评分、剩余尿量、最大尿流率变化以及药物费用。结果:三组在降低IPSS症状评分、增大最大尿流率、减少膀胱剩余尿和缩小前列腺体积上的差异无统计学意义(P>0.05),但单用坦索罗辛组药物费用最低。结论:单用坦索罗辛即可很好地控制BPH。

目的:评价高频热疗治疗、药物治疗、高频热疗结合药物治疗慢性前列腺炎的疗效。方法:将病人分为单纯热疗组、药物治疗组、药物+热疗治疗组,针对有效率及三种慢性前列腺炎治愈率进行比较。结果从统计学上分析单纯热疗组明显优于药物治疗组,药物+热疗组明显优于单纯热疗组,单纯热疗组治疗前列腺痛效果明显。结论:治疗慢性前列腺炎,应用药物+热疗治愈率和有效率明显提高。

Objective To discuss the earlier treatment of fresh post - urethra injury of male. Methods Sixty - nine patients were analyzed by retrospecitve research and all cases were followed - up. Results Thirty - one cases were cured by foley catheter balloon as a pulling and fixing re - union device ( success ratio 62% ) ,earlier urethral anastomosis was expected in 8 cases ( success ratio 66.4% ), single cyst - fistulation was adopted in 2 cases ( success ratio 13.2% ). Conclusion In accordance with the condition of patients, appropriate operation was the key of treatment.

目的:探讨肾窦内肾盂、肾盏加肾下极实质联合切开取石治疗巨大鹿角形结石的疗效。方法:于肾脏背面解剖出肾窦内间隙,用肾盂拉钩拉开暴露肾窦内肾盂并切开取石。若结石不活动,则在拟定肾后下部切口两侧用1号肠线作"U"型缝扎肾实质2～4针(不包括肾盂、肾盏),两针间距1cm,从中间切开肾下部实质,转动结石并取出。取石后用4～0肠线缝合肾盏肾盂切口,1～0肠线间断缝合肾实质切口。结果:本组共68例,其中单例58例,双例10例。结石3.5～6.2cm,最大2例充满全部肾盂肾盏。术后肾功能基本恢复,复查"B"超肾脏积水减轻。结论:肾窦内肾盂、肾盏加肾下极实质切开治疗巨大鹿角形结石操作简单,安全,出血少,对肾脏损伤轻,是治疗复杂鹿角形结石较为理想的方法。