Objective To investigate the technological process of prescription Fuse-1 gel,and estimate the stability and irritation of the gel. Methods The prescription Fuse-1 gel was prepared by mixing prescription Fuse-1 aqueous exacts as main medicine,carbomer 940 and the PEG-4000 as accessories,the triethanolamine as carbomer's neutralizer, laurocapram as transdermal agent,and Kathon as antiseptic to synthesize the gels by the gel method. Constant temperature incubator, refrigerator, room temperature storage and centrifuges were used to evaluate the stability of the gel. pH meter was used to evaluate the pH value of prescription Fuse-1 gel. Irritation and sensitization of the gel was determined by cutaneous stimulation test and skin allergies test. Results The gel samples showed uniform dispersing. No significant changes of the gel appearance, the gel color and the gel viscosity, and stratification and discoloration after the room temperature storage and cold heat-resisting tests. The gel samples did not become coarse, layered or precipitated after centrifugation. The average pH value was (5.96±0.012). Prescription Fuse-1 gel has no stimulation reactions such as erythema, oedema and furfuration on the guinea pig skin, and has no anaphylactic reaction of erythema, oedema on the rat skin. Conclusion The prescription Fuse-1 gel was stable, and did not cause irritation and allergy.

[目的]探求治疗白癜风药物的颜色与药效的关系,以期为治疗白癜风的选方用药与研究提供新思路.[方法]通过查阅相关文献收集临床治疗白癜风的有效中药方剂,对其方药药效、颜色方面的资料进行统计处理和分析.[结果]内服方剂中常用深颜色药物有首乌、补骨脂、丹参、红花、熟地等,外用方剂常用深颜色药物有补骨脂、密陀僧、雄黄、红花、乌梅等.[结论]药物的颜色与药效相关,临床用药应当考虑中药色象因素选用相关药物.

白癜风是一种常见的局限性色素脱失性疾病,世界患病率是0.5～1%[1],临床以大小不同,形态各异的皮肤变白为特征.皮损在面部、头部、双手者高于皮损在躯干不外露处[2],50%的患者于18岁前患病[3],使患者身心受创.笔者通过阅读历代与白癜风相关书籍,并查阅近二十年与白癜风的相关文献,发现临床上中医治疗白癜风多从肝肾不足、肝郁气滞、气血瘀滞辨证分型,分别用滋养肝肾、疏肝理气、活血化瘀之法论治.然而,临床千变万化,部分患者从营卫不和辨证,通过桂枝汤调和营卫之法治愈.本文就营卫不和型白癜风的临床表现、病因、病机及治疗综述如下.

<正>中药色象理论[1]是南方医科大学中医药学院杨柳教授提出的一种表明药材颜色与疗效相关的理论,该理论认为应用浅色药材治疗色素增加类皮肤病(如黄褐斑、皮肤黑变病)、深色药材治疗色素减退类皮肤病(如白癜风)可取得一定的临床效果。这对临床医者在选择用药方面可起到一定指导作用。笔者通过总结分析白癜风外用药物的症型与药材颜色的关系,探究阐述白癜风外用药物与色象理论的关系。