Objective To investigate the effectiveness and safety of endoscopic papillary large-balloon dilation(EPLBD) for juxtapapillary duodenal diverticulum(JPD)combined with large common bile duct stones.Methods A total of 87 patients with juxtapapillary duodenal diverticulum and large common bile duct stones were randomly divided to 2 groups.Forty-five cases received endoscopic papillary large-balloon dilation(EPLBD group) as the treatment group,and 42 cases were treated by conventional endoscopic sphincterotomy(EST group) as the control group.The success rate of stone clearance in a single session,operation time,the rate of mechanical lithotripsy and complications were observed.Results Stone clearance in a single session of 2 groups were 91.1％ (EPLBD group)and 92.9％ (EST group) respectively with no significant difference(P ＞ 0.05).The stone removal time were (25.48 ± 7.92) min in EPLBD group and(35.56 ± 9.23) min in EST group (P ＜ 0.05).The rate of mechanical lithotripsy were 16.3％ and 34.6％ in two groups with significant differences.Rates of bleeding,postoperrative pancreatitis and cholangitis in two groups were similar(P ＞ 0.05).No death happened in any group.Conclusion EPLBD is a safe and effective method for clearance of large common bile duct stones combined with juxtapapillary duodenal diverticulum which can reduce the occurrence of mechanically breaking stone and operation time.

<正>会阴切口感染的预防是近年来产科治疗环节中的重点之一,严重感染发生后会导致会阴切口化脓,全层裂开,且二次缝合效果不好,对产妇造成较大伤害。笔者整理分析了自制中药熏洗方预防产后会阴切口328例感染的疗效,效果满意,现报道如下。1一般资料