Objective To analyze the effect of zhenwu decoction on RASS system activity and serum NT-proBNP and ADH levels in patients with chronic heart failure. Methods A total of 150 patients with chronic heart failure who were admitted to The Second Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, from January 2020 to November 2021 were selected as experimental subjects, and divided into a treatment group and a control group by random number table method, and the single group was set as 75 cases of patients. The control group was treated with conventional western medicine, while the treatment group was additionally treated with zhenwu decoction on the basis of the control group. The clinical efficacy and RASS system activity（serum renin, angiotensin Ⅱ, aldosterone）, precursor brain natriuretic peptide（NT-proBNP） and plasma antidiuretic hormone（ADH） levels before and after treatment were compared between the two groups. Results There was no significant difference in the RASS system activity and serum NT-proBNP and ADH levels before treatment between the two groups（P＞0.05）. The total clinical effective rate in the treatment group was higher than that in the control group, and the levels of serum renin, angiotensin Ⅱ, aldosterone, and serum NT-proBNP and ADH after treatment were lower than those in the control group, with significant differences between groups（P＜0.05）. Conclusion Zhenwu decoction is beneficial to reduce the activity of RASS system and the levels of serum NT-proBNP and ADH in patients with chronic heart failure, and improve the clinical treatment effect.

目的 研究益气活血通脉颗粒治疗冠心病心绞痛(心血瘀阻型)的疗效及对患者内皮功能和相关生化指标的影响.方法 选取2018年11月—2020年2月因冠心病(心血瘀阻型)来江西中医药大学第二附属医院院治疗的患者(曾有心绞痛病史)80例,以随机原则分为观察组与对照组,每组各40例.其中对照组给予常规降血脂药,突发心绞痛时舌下含服硝酸甘油,观察组在其基础上给予益气活血通脉颗粒.以患者治疗前后的血管内皮功能与相关生化指标作为治疗评测标准.结果 治疗2周后、2组患者病情均有所改善,但观察组各项心脏生化指标下降幅度高于对照组(P<0.05),血管内皮功能恢复更佳(P<0.05),总有效率达92.5％(37/40),高于对照组的70％(28/40)(P<0.05).结论 益气活血通脉颗粒有利于改善冠心病患者血管内皮功能,增加冠张动脉有效灌注,降低心绞痛突发概率,提高治疗效果.

目的:观察口服枳实薤白桂枝汤加减对稳定型冠心病的疗效.方法:选取江西中医药大学第二附属医院2020年1月至2021年1月门诊及住院部诊断为稳定型冠心病共80例,分为对照组与观察组,分别40例.对照组西医内科规范治疗,观察组在对照组基础上加用枳实薤白桂枝汤加减治疗.通过对比两组治疗前后心脏运动耐量、心绞痛积分、中医症候积分、血管内皮生长因子(VEGF)、血清内皮素-1(ET-1)和C反应蛋白(CRP)水平来对比两组治疗效果.结果:观察组治疗后心脏运动耐量、VEGF水平高于对照组,差异有统计学意义(P<0.05);而心绞痛积分、中医症候积分、ET-1和CRP水平低于对照组,差异有统计学意义(P<0.05).结论:枳实薤白桂枝汤加减治疗稳定型冠心病疗效更佳,在稳定病变、减少不良反应及改善预后方面显示出一定的优势.

目的:对比益气活血通脉颗粒与复方丹参胶囊对稳定性心绞痛的治疗效果差异.方法:选取2018年1月-2018年5月收治的80例稳定性心绞痛患者,以信封法将患者随机分入对照组与研究组,两组患者各40例.其中,对照组使用复方丹参胶囊,研究组使用益气活血通脉颗粒.对比两组的临床疗效、心率以及心绞痛发作次数.结果:研究组治疗总有效率92.5％,对照组则为72.5％,研究组高于对照组;同时,研究组心率低于对照组,心绞痛发作次数少于对照组,差异有统计学意义(P<0.05).结论:与复方丹参胶囊相比,益气活血通脉颗粒对稳定性心绞痛有着更为显著的治疗效果.

Objective To investigate the efficacy of edaravone combined with magnesium sulfate,and large doses of naloxone as the treatment of acute stroke.Methods 112 cases of acute stroke patients were divided into the observation group and control group with 46 cases in each group according to random number table.The control group was given edaravone;the observation group combined with magnesium sulfate,and large doses of naloxone.Neurological function,hemorheological indexes and efficacy were compared between the two groups.Results The total effective rate of the observation group was 86.96%(40/46),of the control group was 60.87%(36/46),the difference was statistically significant(P<0.01);the NDS score and hemorheological indexes of two groups were significantly lower after treatment(P<0.05),the observation group decreased more significantly than the control group(P<0.05);there were no adverse reactions in both groups.Conclusion Edaravone combined with magnesium sulfate,and large doses of naloxone treating acute stroke can improve nerve function quickly,promote blood circulation and significantly improve the efficacy,without adverse reactions.

目的对采用针刺与牵引联合的方法对患有腰椎间盘突出症的军人伤病员进行治疗的临床效果进行比较分析。方法抽取200例在我院就诊的患有腰椎间盘突出症的临床确诊伤病员病例,将其随机分为A、B2组,平均每组100例。A组伤病员采用牵引方法进行治疗;B组伤病员在A组基础上采用针灸刺激穴位(悬枢、命门、腰阳关)的方法进行治疗。对2组伤病员的疼痛评分、临床治疗效果、并发症和不良反应现象进行比较分析。结果 B组伤病员的临床治疗效果与A组伤病员比较,其有效率明显高出很多,有显著的统计学差异(P<0.05);该组伤病员的疼痛评分明显低于A组伤病员,有显著的统计学差异(P<0.05)。结论采用对针刺与牵引联合的方法对患有腰椎间盘突出症的军人伤病员进行治疗的临床效果十分明显,可以使伤病员的疼痛感显著减轻,在治疗过程中不会出现特殊的并发症和不良反应现象,可以作为进行临床对该类伤病员进行治疗的首选方法。