热性惊厥是儿科常见急症,为探讨急性上呼吸道感染致热性惊厥患儿心肌酶谱变化,我们对2010年1月至2011年6月我院收治的急性上呼吸道感染致热性惊厥患儿88例的心肌酶谱资料进行回顾性分析,并与同期急性上呼吸道感染且体温＞38.5℃而无惊厥的45例患儿的心肌酶谱资料作为对照分析。
支原体肺炎(mycoplasma pneumoniae pnenmonia,MPP)是由肺炎支原体(Mycoplasma pneumoniae,MP)引起的肺炎.MPP起病缓,有发热、阵发性刺激性咳嗽,少量黏液性或黏液脓性痰.MPP多发于儿童或青少年,占肺炎总数的15％～30％[1].大多数MPP患儿血液中单核细胞百分比高于正常值(3.5％～7.9％),可达65.3％,这是否提示具有肺炎症状且伴有单核细胞增多的患儿为MP感染.为此,我们对2000-2011年住院治疗的MPP患儿的临床资料进行分析,报告如下.
目的探讨外周血单核细胞增多与儿童肺炎支原体肺炎(MP)的临床特点及治疗转归。方法我科收治住院治疗的儿童肺炎支原体肺炎539例临床资料进行分析。结果 539例支原体肺炎,治疗给予阿奇霉素10mg/kg.d,静滴,539例患儿中有10例用药不满意,临床症状改善不明显,有2例患儿遗留左上肺叶肺不张,另529例(98.1%)预后良好。结论临床上MP感染的表现可为多样性,465例(86.2%)在MP感染中,外周血单核细胞增高出现时间早,增高的比例往往与MP-IgM阳性比呈正相关,单核细胞增多是否参与细胞免疫反应,有待进一步研究探讨。
Objective:To investigate the drug sensitivity of mycoplasma pneumoniae isolated from patients.Methods:Samples of throat swab were cultivated in selective culture medium,and then they were detected by PCR.Mycoplasma pneumoniae were mixed with different quantity of antibiotics.If one drug could kill the microorganism,the color of the media would not change.Results: One clinical mycoplasma pneumoniae type was isolated successfully.When the concentration of azithromycin,erythromycin and cefuroxime sodium were diluted to 31 μg/mL,125 μg/mL,500 μg/mL,respectively,mycoplasma pneumoniae were supressed.Ceftriaxone sodium,mezlocillin and ampicillin had no effect on the growth of mycoplasma pneumoniae.Conclusions: The growth of mycoplasma pneumoniae isolated from throat swab samples is inhibited easily by azithromycin.Erythromycin and cefuroxime sodium also had inhibitory effect on mycoplasma pneumoniae.
目的调查分析儿科住院患者抗生素的应用情况,为临床合理使用抗生素提供参考。方法应用回顾性调查研究方法,提取儿科上呼吸道感染病例261例,对抗生素的使用情况进行统计和分析。结果儿科上呼吸道感染住院病人抗生素使用率过高,严重超出卫生部和WHO的标准;口服药品使用比例低;病原学检查不及时,全部上感住院患者均未做药物敏感度试验。结论根据细菌学检查和药物敏感试验,安全、有效、经济、合理的选择用药品种及用药方式,使疾病治疗由经验治疗转为病原治疗。
Objective To study effect of pathological jaundice on neonate's myocardium.Methods All neonates were diveded into treatment group 1 and treatment group 2.The changes of neonates in serum total bilirubin,myocardial enzymes,electrocardiogram,ultrasound cardiogram in two treatment groups were retrospectively analyzed.Results ①The serum AST,LDH,CPK,CK-MB of neonates in the two groups were higher at varied extent than normal,but there were no significant differences between the two groups(all P0.05);② No obvious abnormalities in electrocardiogram and ultrasound cardiogram were found in the two groups and no obvious symptoms and signs of myocardial damage in clinic were seen;③ After 7 days treatment,there were no significant differences in AST,LDH,CPK,CK-MB of the neonates between the two treatment groups(all P0.05).Conclusion Neonatal pathological jaundice doesn't do serious harm to myocardium of the neonate.Routine myocardium protection treatment is not needed.The diagnosis of neonatal myocardial damage shouldn't only depends up elevated myocardial enzyme values,but also comibines clinical manifestations of the neonate,abnormalities in ultrasound cardiogram and EEG to analyze all-round and judge synthetically.
