Objective To analysis the affect of anxiety on the outcome of Acarbose intervention in prediabetes. Methods Sixty -eight patients with prediabetes who were screened in Anhui No. 2 Provincial People''s Hospital Huangshan Road Physical Examination Center and Outpatient Department from June 2020 to June 2022 were selected. The anxiety of the patients was assessed by Self-rating Anxiety Scale (SAS). General and clinical data of the patients were collected by questionnaires to analyze the effect of anxiety on the outcome of Acarbose intervention in prediabetes. Results Anxiety group (35 cases) and non-anxiety group (33 cases). After Acarbose treatment, the fasting blood-glucose (FBG), 2-h postprandial blood glucose (2 hPG) and glycosylated hemoglobin (HbA1c) in non-anxious prediabetes patients were better than those in prediabetes patients with anxiety. After treatment with acarbose, FBG, 2 hPG,HbA1c decreased statistically significantly compared with before the intervention. According to anxiety level, which divided all patients with prediabetes into anxiety and non-anxiety groups,Before the acarbose intervention, sex, age, FBG, 2 hPG,HbA1c comparison, the difference was not statistically significant (P ＜ 0.05). After the acarbose intervention, FBG, 2 hPG, and HbA1c were lower in the non-anxiety group than those in the anxiety group (P ＜ 0.05). Conclusion The effect of Acarbose treatment in prediabetes is better in non-anxious patients than anxious patients. At the same time, improving blood glucose has certain effect on reducing the anxiety level of prediabetes patients.

贫困地区群众因病致贫、返贫问题突出.医学院校应坚持国家健康扶贫工程中的基本原则,充分发挥自身医疗和教育的双重资源优势,通过培训基层医务人员、健康宣教和义诊等路径,落实好健康扶贫任务,着力破解农村因病致贫、因病返贫率高的难题.

目的 研究C-反应蛋白(CRP)与2型糖尿病的关系及血脂水平的变化及其临床意义.方法 对66例2型糖尿病患者和49例健康体检者同时检测CRP、甘油三酯(TG)、胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C).结果 2型糖尿病组及合并慢性并发症组C反应蛋白(CRP)、LDL-C、TC(mmol/L)、TG(mmol/L)含量均明显升高,与健康对照组相比有非常显著性差异(P<O.O1).HDL-C浓度低于健康对照组,差异也有统计学意义(P＜0.05);2型糖尿病患者66例的空腹血清CRP对TC、TG、HDL-C、LDL-C进行性相关性分析显示,CRP与TG、LDL-C呈正向直线相关,CRP与HDL-C呈负向直线相关,CRP与TC无明显直线相关性.结论 2型糖尿病患者CRP升高,与血清TG、TC、LDL-C、HDL-C密切相关,CRP对预测糖尿病及其并发症及监测疗效上有重要价值.

目的观察并分析碘-131治疗甲状腺功能亢进症合并2型糖尿病临床疗效。方法将72例住院随机分成观察组36例和对照组36例,所有患者根据糖尿病病情需要口服降糖药或使用胰岛素制剂。观察组给予131I治疗,对照组给予口服甲巯咪唑30mg/d,2～3次/d,或丙基硫氧嘧啶300～450mg/d,2～3次/d,逐渐减至维持量。随访1～12个月,第1、3、6、9和l2个月各1次。结果治疗1.5年后,观察组总有效率为86.11%,明显高于对照组,两组比较差异有统计学意义(P<0.01)。两组甲状腺激素水平及血糖指标均有明显改善,差异有统计学意义P<0.01。观察组甲状腺功能减低发生率明显高于对照组,甲状腺功能亢进症复发率明显低于对照组,差异有统计学意义P<0.01。结论碘-131治疗甲状腺功能亢进症合并2型糖尿病疗效好、复发率低,且方便快捷。

Objective Observed the clinical efficacy and safety of insulin pump continuous subcutaneous infusion in the treatment of patients with type 2 diabetes.Methods The patients in poor control of blood glucose were chosen in our hospital,who were randomly divided into the therapy group of 80 cases treated with insulin pump,and the control group of 80 cases using the traditional method of multiple subcutaneous insulin infusion,the therapeutic efficacy and safety were evaluated in the patients of the two groups.Results The fasting and 2 hours postprandial blood glucose,blood sugar compliance days,insulin dosage and the occurrence of low blood sugar of CSⅡwere better than MSⅡgroup,the differences were statistically significant(P<0.05).Conclusion Enhanced insulin pump therapy in patients with blood sugar steady and ideal control,reduction of night and dawn phenomenon of low blood sugar,blood sugar compliance to reduce the number of days,insulin therapy was an effective way.

The appropriate scaffold is one of the there major factors of tissue engineering.In this paper we discussed the application of natural scaffold materials including collagen,chitosan,HA,coral and silks in tissue engineering.

组织工程学是近年来发展起来的一门新学科,是材料学、工程学和生命科学共同发展并相互融合的产物,其最基本的思路是在体外分离、培养细胞,将一定量的细胞接种到具有一定空间结构的支架上,通过细胞之间的相互黏附、生长繁殖、分泌细胞外基质,从而形成具有一定结构和功能的组织或器官[1],因而,充足的种子细胞、合适的支架及促进种子细胞在支架上增殖分化的因子便成为组织工程的三大要素.