Objective:By detecting Homocysteine metabolic enzymes N5,10-methylenetetrahydrofolate reductase(MTHFR) C677T and cystathionine B-synthase(CBS) G919A and C572T gene mutations,we study the relation of MTHFR and CBS gene Polymorphism of patients with pregnancy hypertension and analyze the role of genetic factors in this disease.Methods: 4 ml peripheral vein blood of pregnant woman on an empty stomach was taken and serum was isolated.Homocysteine concentration was measured by enzyme circulation method and small molecule capture technology.Folic Acid and Vit B12 was measured by chemiluminescent immunoassay.DNA was isolated from the whole blood.MTHFR 677 genetype was analzed by PCR and sequencing.CBS 919 and CBS 572 genotype was analyzed by Allele-specific amplificafion(ASA).The data was analyzed by using statistical software SAS.Results: There is statistical significance at gene MTHFR 677 and CBS 572 between group with pregnancy hypertension and the control group,but there is no statistical significance at gene CBS 919.Between two groups there is statistical significance in Hcy and folic acid,but there is no statistical significance in Vit B12.Conclusion: Pregnancy hypertension may be caused by genetic factors and folic acid deficiency.

子宫内膜异位症(EMS)是当前妇产科临床最为关注的疾病之一,发病率高达10%～15%,近年有逐年上升的趋势,在不孕与盆腔疼痛的患者中占20%～90%[1].最常发生部位为卵巢,形成卵巢子宫内膜异位囊肿.2005-2006年,作者采用腹腔镜手术联合药物治疗卵巢子宫异位囊肿47例,取得满意疗效,现报道如下.

妊娠期高血压疾病是妊娠期特有的疾病,我国发病率为9.4%,是孕产妇和围生儿死亡率的主要原因.

目的:了解基层医务人员掌握和应用中医药知识技能的内容和程度,对中医药知识的需求方向和接受培训的方式,探讨适应基层中医药知识技能培训的有效方式.方法:采用全而调查与抽样样本调查相结合,问卷调查和实地访谈相结合.结果:基层医务人员有一定的中医药知识技能基础,接受培训方式以参加培训班进行常见病、多发病的辨证施治培训为主.结论:开展突出重点,分层次的中医药知识技能培训是符合基层实际的有效培训方式.

妊娠期高血压是妊娠期特有的疾病,发病率9.4%,严重影响母婴健康,是孕产妇和围生儿病率及死亡的主要原因.近年来的研究表明,高同型半胱氨酸血症可导致血管内皮细胞损伤[1],并可能是妊娠期高血压发病的原因之一.本研究拟测定孕产妇血清中同型半胱氨酸(HCY)水平,探讨其与妊娠期高血压发病的关系.

目的观察甲氨蝶呤联合米非司酮加中药治疗宫外孕临床效果。方法94例宫外孕患者随机分为治疗组与对照组。治疗组给予甲氨蝶呤联合米非司酮加中药治疗,对照组给予甲氨蝶呤加米非司酮治疗。结果治疗组治愈率94%,对照组91%,2组比较无显著性差异(P>0.05)。血β-HCG值下降至正常所需时间分别为(14.62±9.24)d、(23.14±11.07)d,2组比较有显著性差异(P<0.01)。结论甲氨蝶呤联合米非司酮加中药治疗能明显缩短血β-HCG值恢复正常水平的时间,降低输卵管破裂可能,值得临床推广应用。

女性,患者,37岁,体健.住院号:2763.因下腹痛作妇检时发现子宫右侧圆形光滑软组织肿块,随作CT扫描.在膀胱高度充盈下自耻骨联合向上至第5腰椎平面平扫,层距层厚各10mm,于子宫体平面加扫5mm层.盆腔内未见占位性病灶.在充盈的膀胱顶上层,平第1骶椎上缘平面见一圆形囊性肿块,边缘光滑,中心CT值-50HU(图1.A,B).嘱病人排空膀胱后再次CT平扫,此时发现在平两侧股骨头上缘平面,在子宫面侧,与子宫体相连一囊性圆形肿块,边缘光滑,大小49×46×45mm,中心CT值-115HU---50HU(图2.A,B).确定肿块来自右卵巢,与临床妇检发现肿块系同一病灶.CT诊断右卵巢囊性畸胎瘤. 手术发现:右卵巢囊性增大约50×40×40mm,表面光滑、活动无异常.标本剖面见瘤内充满脂肪及毛发.病理诊断(0372):(右卵巢)囊性畸胎瘤.

宫外孕与盆腔炎性包块在临床上经常遇到,两者在CT图像上表现相似,但又各具特点,陈旧性宫外孕与炎性包块有时难于鉴别.本文收集经手术病理证实的6例宫外孕与8例盆腔炎性包块病人,就CT表现特征分析如下.