Objective:To figure out the persistent time of IgG antibody to SARS-CoV in SARS cases.Methods:The IgG antibodies to SARS-CoV were tested by indirect ELISA in sera samples of 176 confirmed SARS cases.Results During days of 0-7,8-14,15-21,after symptoms onset,the cumulated positive rate of SARS-CoV IgG was 11.76%,38.46%,77.27% respectively.In 22-30 days,the cumulated positive rate reaches 91.67%,then kept at the level above 90% until the third months when positive rate is 100%.The cumulated positive rate of SARS-CoV IgG in 1 year was declined to 93.88%,but 88.89% of SARS cases was still kept positive IgG antibodies to SARS-CoV after 2 years.The increasing speed of optical density value of SARS-CoV IgG was slower than that of cumulated positive rate of SARS-CoV IgG.The curve of optical density value was intersected with the peak of the curve of positive rate during 90～120d,then declined by 22% from 6 months and declined by 40% in 1 and 2 years.Conclusion:The IgG antibodies to SARS-CoV can be maintained for more than 2 years wheile the decreasing trend of titer for SARS-CoV IgG occur.

目的提高维持无脊髓灰质炎(脊灰)监测工作质量,保持无脊灰状态.方法按照<2003～2010年全国保持无脊髓灰质炎状态行动计划>的要求,开展口服脊灰疫苗(OPV)常规免疫、强化免疫和急性弛缓性麻痹(AFP)监测工作.结果2004年报告163例AFP病例,分布在11个市,91个县,15岁以下儿童中非脊灰AFP病例报告发病率1.89/10万,合格粪便标本采集率92.64%,标本送检及时率95.71%,随访表送达及时率100.00%.市、县级疾控机构"零"病例旬报及时率97.22%和92.20%.OPV常规免疫接种率99.35%,强化免疫接种率第一轮96.98%,第二轮96.35%.结论2004年AFP病例监测各项指标均达到并保持在世界卫生组织无脊灰证实标准以上.

目的为了解忻府区脊髓灰质炎(脊灰)的免疫状况做出科学的评价.方法采用中和抗体测定法.结果脊灰Ⅰ、Ⅱ、Ⅲ型中和抗体阳性率分别为95.83%、97.50%、96.67%;Ⅰ、Ⅱ、Ⅲ型抗体几何平均滴度(GMT)分别为1:22.89、1:18.81、1:17.60.结论忻府区健康人群脊灰中和抗体阳性率均较高,但GMT偏低.

This study is to improve the surveillance quality of polio eradication and keep polio-free status. According to the requirement of “2003-2010 Actionplan on Sustaining Polio-free Status in the Whole Country, OPV routine immunization, catch-up immunization and AFP surveillance were carried out. The results showed that 174 AFP cases reported in 2003 distributed in 82 counties of 11 cities. The reported incidence of non-polio AFP cases was 2.03 per 100 000 children under 15 years old. The collection rate of adequate stool specimens was 96.55%, the specimen delivery rate in provincial laboratory within 7 days was 95.40%, and the follow-up visiting form timely arrived rate was 99.43%. The timely reporting rate of zero AFP case by the city and county EPS were 95.70% and 93.00% respectively. The OPV routine immunization coverage was 99.31%, catch-up or supplementary immunization coverage for the first round was 97.81%, the second round was 98.18%. In 2003, all the indicators of AFP surveillance have already reached and kept above the target of WHO's polio-free certification standard.

山西省2000年共报告15岁以下儿童急性驰缓性麻痹(AFP)病例148例,发病率为1.66/10万,已连续6年达到世界卫生组织(WHO)和卫生部规定的1/10万标准.为证实无脊髓灰质炎提供科学依据,现将山西省2000年脊灰病原学监测结果报告如下.

山西省于2000年3、4月在92个县(区、市)进行了2轮口服脊髓灰质炎疫苗(OPV)“扫荡”式免疫活动,其模式不同于OPV强化免疫和常规免疫.将此期间采集的35例急性弛缓性麻痹(AFP)病例粪便标本病毒分离结果,与近年OPV常规免疫和强化免疫期间采集的AFP病例粪便标本(27例和39例)的病毒分离结果作了比较.“扫荡”式免疫期间的AFP病例粪例标本的PV分离率为28.6%(10/35),明显高于常规免疫的3.7%(1/27)和强化免疫的5.1%(2/39).将“扫荡”式免疫期间,在“扫荡”式免疫地区采集的AFP病例粪便标本25例及其接触者粪便标本20份,和非“扫荡”式免疫地区采集的10例AFP粪便标本及25份接触者粪便标本的病毒分结果也作了比较分析,“扫荡”式免疫地区AFP病例和接触者的粪便标本中PV分离率分别为36.0%和10.0%,均明显高于非“扫荡”式免疫地区的10.0%和0.可见不同免疫模式对PV分离率有一定影响.

The quality and quantity of the indicators completed in laboratory for AFP case surveillance are the key basis for confirmation of poliomyelitis elimination. The consistency evaluatin of virus isolates identified in laboratories at both provincial and national levels was made by Kappa test. The results were K=0.864, U=13.541, P<0.0001, which showed that virus isolation identified in laboratories at both provincial and national levels had good consistency. Coincidence rate was 91.30%.

山西省卫生防疫站脊髓灰质炎(脊灰)实验室从1998年7月正式使用L20B细胞,并同时使用RD和Hep-2细胞进行急性弛缓性麻痹(AFP)病例病原学监测,为了解同时使用3种细胞对AFP病例病原学监测结果的影响,将308例AFP病例粪便标本在3种细胞上的分离状况进行比较分析.同时使用3种细胞共分离到脊灰病毒(PV)20份,其中RD细胞分离到14份,L20B细胞16份,Hep-2细胞8份,总分离率为6.5%.分离到非脊灰肠道病毒(NPEV)65株,其中RD细胞30株,Hep-2细胞48株,分离率为21.1%.结果显示,同时使用3种细胞对提高PV检测灵敏度和NPEV分离率,保证脊灰实验室监测质量有重要意义.

<span id="ChDivSummary" name="ChDivSummary" class="abstract-text">太原地区正常儿童呼吸道合胞病毒感染的调查山西省卫生防疫站（太原０３００１２）贾芙蓉，芦天林，马建瑞，吴立平，常一华米尔英（指导）山西省呼吸道合胞病毒（ＲＳＶ）毛细支气管炎、肺炎疑似病例每年冬春季常有发生，并于１９８４年在太原地区得到了病原学证实［１］...</span>