Objective:To figure out the persistent time of IgG antibody to SARS-CoV in SARS cases.Methods:The IgG antibodies to SARS-CoV were tested by indirect ELISA in sera samples of 176 confirmed SARS cases.Results During days of 0-7,8-14,15-21,after symptoms onset,the cumulated positive rate of SARS-CoV IgG was 11.76%,38.46%,77.27% respectively.In 22-30 days,the cumulated positive rate reaches 91.67%,then kept at the level above 90% until the third months when positive rate is 100%.The cumulated positive rate of SARS-CoV IgG in 1 year was declined to 93.88%,but 88.89% of SARS cases was still kept positive IgG antibodies to SARS-CoV after 2 years.The increasing speed of optical density value of SARS-CoV IgG was slower than that of cumulated positive rate of SARS-CoV IgG.The curve of optical density value was intersected with the peak of the curve of positive rate during 90~120d,then declined by 22% from 6 months and declined by 40% in 1 and 2 years.Conclusion:The IgG antibodies to SARS-CoV can be maintained for more than 2 years wheile the decreasing trend of titer for SARS-CoV IgG occur.
为了解SARS冠状病毒(CoV)在山西省不同人群中的感染状况及分布规律,进行了抗SARS-CoV抗体检测和分析.
目的 比较成人接种不同种类、不同免疫程序、不同剂量狂犬病疫苗的免疫效果。方法 应用ELISA间接法对1991~2001年间在我站门诊注射狂犬端病疫苗的2172例成人进行抗体检测。结果 常规5针法狂犬病疫苗的抗体阳性率为70.08%,浓缩狂犬病疫苗的阳性率为83.05%,人用纯化狂犬病疫苗的阳性率为97.06%。经统计学处理有非常显著性(P<0.001)。浓缩狂犬病疫苗7针法阳性率为96.19%,与人用纯化狂犬病疫苗常规5针法比较,差异无显著性。结论 提示成人注射人用纯化狂犬病疫苗效果优于浓缩狂犬病疫苗,但抗体阳性串仍未能达到100%,对结果阴性者应及时补种疫苗。
<span id="ChDivSummary" name="ChDivSummary" class="abstract-text">太原地区正常儿童呼吸道合胞病毒感染的调查山西省卫生防疫站(太原030012)贾芙蓉,芦天林,马建瑞,吴立平,常一华米尔英(指导)山西省呼吸道合胞病毒(RSV)毛细支气管炎、肺炎疑似病例每年冬春季常有发生,并于1984年在太原地区得到了病原学证实[1]...</span>