肿瘤严重威胁着人类健康,现代医学以西医治疗为基本疗法,但西医治疗不良反应大、成本高,给患者带来身体痛苦和沉重的经济负担.随着中医药的发展,人们从中药中不断发现抗肿瘤有效成分,中药在抗肿瘤方面显示出很大的优势.本文对抗肿瘤中药及其有效成分进行了总结,将抗肿瘤中药分为扶正补益药、活血化瘀药、清热解毒药、有毒中药等四大类,并对其抗肿瘤机理进行了分析.
糖尿病肾病是糖尿病常见的微血管并发症，也是导致糖尿病患者死亡的重要原因。本文根据糖尿病肾病症型，分别从气阴两虚、脾肾阳虚、肝肾阴虚、痰瘀互结等方面进行研究，揭示中药治疗糖尿病肾病的研究价值及进展。
The interactions of icariin and icarisideⅠ with bovine serum albumin(BSA) under simulated physiologic conditions was investigated by fluorescence spectroscopy.The binding constants(KA),number of binding sites(n) of icariin / icarisideⅠ with BSA,and other thermodynamic parameters(△G,△H and △S) were calculated.The experimental results showed that both icariin and icarisideⅠ significantly quenched the intrinsic fluorescence of BSA through a single static process by forming a ground state complex.The values of KA and n at different temperatures(17 ℃,27 ℃,37 ℃) indicated that icarisideⅠ bound BSA stronger than icariin could.The thermodynamic measures suggested that the forces for icariin to bind BSA were mainly the hydrogen bonding and van der Waals force,whereas the hydrophobic and electrostatic interactions were the leading forces to form icarisideⅠ and BSA complex.In addition,conformational changes of BSA were observed from the synchronous fluorescence spectra upon the binding of icariin and icariside I.
Lutein is one of the carotenoids which exist widely in the nature.It is a kind of safe pigment.Because of the variety of biological activity,lutein has a wide application prospect in the future.The research progress in preparation and biological activity of lutein were introduced,in order to provide the reference for its further study.
