Objective To compare the effect between the group of 5-selective serotonin reuptake inhibitor（SSRIs）treatment and the group of SSRIs combining cognitive behavioral therapy（CBT）.Methods Eighty patients meeting the Diagnostic and Statistical Manual of Mental Disorders,Fourth edition criteria for obsessive-compulsive dis-

生活中有很多事情会让我们产生不好的情绪,那什么样的想法会引起人们的焦虑,并迫使人们反复地做一些事情来缓解焦虑呢? "如果门没关好怎么办?我必须百分之百确定门关好了"; "为什么我会产生这种不道德的想法?这说明我是一个坏人"; "门把手上面全是细菌,如果我摸了,我就会被传染疾病"; "万一椅子上有针头,扎到我怎么办"? "我不能去公园,那里经常有流浪狗出没,它们会咬我".

Objective To explore the etiopathogenisis, influencing on mother and infant, and treatment of gestination complicated anemia. Method Gestation process and complications, growth and development of fetus were analyzed by statistics of anemia causes and degree of 90 cases with gestation complicated animia. Results Hematological system diseases accounted for a certain proportion in the causes of gestation complicated anemia and gestational hemopathy can be caused by many kinds of hematopathy. The degree of gestation complicated anemia was mild or middling usually, severe anemia was less. Thrombocytopenia was more caused by hematopathy, and middle or sever degree was more. Gestation complicated anemia, hematological system disease and thrombocytopenia could increase the harmful effects on mother and fetus. Conclusion We should enhance the antenatal examination, in order to get early diagnosis and treatment, select the correct delivery method to reduce the mortality in perinatal phase.

目的 测定TORCH感染孕妇的宫内垂直传播率和子宫蜕膜感染率.方法 在有不良妊娠结局的孕妇中取IgM阳性患者作为研究对象,用定性PCR方法检测绒毛和蜕膜中TOX(弓形虫)-DNA,CMV(巨细胞病毒)-DNA,HSV-2(单纯疱疹病毒2型)-DNA的阳性率;用荧光定量PCR方法检测绒毛和蜕膜中RV(风疹)-RNA的阳性率.结果 132例有不良妊娠结局孕妇中血清TORCH IgM阳性例数分别为:TOX 25例,RV 15例,CMV 19例,HSV-2 16例.其绒毛PCR检测阳性例数分别为:TOX 11例,RV 3例,CMV 9例,HSV-25例;宫内垂直传播率为TOX 44.00%(11/25),RV 20.00%(3/15),CMV47.37%(9/19),HSV 31.25%(5/16).其蜕膜PCR检测阳性例数分别为:TOX 8例,RV 2例,CMV 8例,HSV-2 3例;蜕膜感染率为TOX 32.00%(8/25),RV 13.33%(2/15),CMV 42.11%(8/19),HSV 18.75%(3/16).绒毛检测组和蜕膜检测组构成比相比较,两组构成比相同(P＞0.05).结论 ①孕期母体TORCH感染具有很高的宫内垂直传播率,其中以CMV为最高;②孕期母体TORCH感染其蜕膜的感染率也很高.母体蜕膜的TORCH感染是胎儿宫内感染的重要原因之一。