1病例资料 女性,26岁,因反复发作反酸伴意识丧失14年入院.病人12岁起,反复出现发作性反酸,继之愣神、咂嘴、摸索,呼之不应,1 ～2 min后意识丧失、口吐白沫、四肢抽搐,持续数分钟,单独或联合服用苯妥英钠、卡马西平、丙戊酸钠等药物无效,几乎每天都发作,多时每天6～7次.神经系统检查及头部MRI未见异常,长程视频脑电图监测到癫痫发作,发作期右颞叶首先出现棘-慢波并向双侧扩散,发作间期可见双侧慢波.诊断:难治性癫痫,颞叶内侧型癫痫.

目的 探讨显微血管减压术治疗面肌痉挛的疗效及预后.方法 回顾采用显微血管减压术治疗的286例面肌痉挛患者,分析其临床表现、手术效果和并发症之间的关系,并于术后半年进行电话随访和来院复查,分析其长期的疗效.结果 286例患者起病时均表现为单侧面部肌肉阵发性、不自主、无痛性抽搐,随病程延长呈逐渐加重的趋势.本组术中均能见到有动脉或静脉血管异常而压迫面神经根出脑干处.术后随访6月至1年,230例症状完全缓解,52例明显减轻,4例手术无效.结论 显微血管减压术是治疗面肌痉挛的一种安全而有效的手术方法.

目的 探讨经翼点入路显微手术切除巨大型垂体腺瘤的技术方法.方法 回顾性分析收治的巨大型垂体腺瘤患者52例,肿瘤直径均＞3 cm,向鞍上及鞍周发展.对患者均采用显微镜下经翼点硬膜内开颅切除肿瘤,随访观察其疗效.结果 肿瘤全切除45例,次全切除7例.术后并发鞍区积气10例,多饮、多尿8例,脑膜炎2例,瘤床少量出血1例,上述并发症均经治疗后痊愈.本组患者视力术后均有不同程度恢复,20例垂体激素增高者术后有16例降至正常范围,无死亡病例.术后均随访6个月至3年,肿瘤残余与复发患者8例,均给予伽马刀治疗;术后6个月的垂体泌乳素水平仍高于正常者4例,予溴隐亭治疗后恢复正常.结论 对巨大型突入鞍上和鞍旁的垂体腺瘤,可采用经翼点入路显微手术方式切除,其疗效满意;术后应定期随访观察.

Objective To analyze and conclude the motor function of cerebral palsy children patients undergoing umbilical cord mesenchymal stem cells transplantation.Methods 97 cerebral palsy children patients undergoing umbilical cord mesenchymal stem cells transplantation.Neurotrophic factors and physical therapy were necessary.Investigate the healing process in 6～12 month,average 9.5month.Gross Motor Function Measure-88(GMFM-88) was applied for motor function assessment;SPSS v18.0 statistical software was used for analyzing the results.Results After one stem cell treatment course,the motor functions of children patients improved at different levels comparing before transplantation;and the healing process were keeping improved after treatment 6 month and more.Conclusion Stem cell transplantation is safe and effective,which can improve cerebral palsy children patients’ motor function significantly;the best effective curative effect after graft 6 month but therapeutic mechanism needs to investigate and research in depth in the future.

脑卒中是中老年人群的常见病、多发病,我国每年死于脑卒中的病人高达100万,文献报道75.00%的病人有不同程度的后遗症,40.00%的病人严重致残,给社会、家庭带来沉重负担和巨大的痛苦.因此防治脑卒中,降低发病率和复发率是当务之急.