目的:探索局部应用注射用重组人白细胞介素11联合护理治疗鼻咽癌放射性口腔炎的效果.方法:选取2014年7月-2016年7月笔者所在医院收治的120例鼻咽癌放射性口腔炎患者,将患者动态随机化分为两组,两组患者60例,对照组和观察组分别实施常规护理和常规护理联合注射用重组人白细胞介素11治疗.结果:观察组患者咀嚼吞咽功能评分[(1.45±0.69)分]、疼痛评分[(1.36±0.61)分]、不良事件发生率(3.33%)、依从性(96.67%)、满意率(100%)、口腔黏膜损伤Ⅰ度率(75.00%)均优于对照组患者,差异有统计学意义(P<0.05).结论:注射用重组人白细胞介素11联合护理干预在鼻咽癌放射性口腔炎患者中效果显著.

目的 探讨责任制优质护理全程追踪模式对宫颈癌化疗后癌因性疲乏及睡眠障碍的影响.方法 随机选取我院收治的宫颈癌化疗患者60例,将其随机均分为对照组与观察组,对照组患者实施常规护理干预,观察组患者实施责任制优质护理全程追踪护理干预.结果 观察组患者的SPIEGEL量表评分明显低于对照组,癌因性疲乏量表评分明显低于对照组,差异均有统计学意义(P<0.05).结论 针对宫颈癌化疗后患者应用责任制优质护理全程追踪模式护理干预,能够有效降低患者的睡眠障碍及癌因性疲乏,值得临床推广应用.

Objective:To establish a method for the determination of 25 kinds of organophosphorus pesticides residuces in fruits and vegetables by ASPE/GC-MS.Methods:The samples were extracted with acetonitrile solution,then the extract was purified through ASPE.The collected solution was analyzed by GC–MS.Results:25 kinds of organophosphorus pesticides gave good linearities in the range of 0.05 mg/kg~5.0 mg/kg(r>0.99).The minimum detection limint was 0.004 mg/kg.The recovery rate and RSD were 80.2%~98.7% and 1.1%~4.8% at 0.5 mg/kg respectively,and 74.2%~99.8% and 1.5%~6.8% at 1.0 mg/kg respectively.Conclusion:The method is simple,rapid with effective purification and high recovery.It is suitable for the determination of multiple organophosphorus pesticides residuces in fruits and vegetables.

<正>碘缺乏病(IDD)是自然环境缺碘使人体摄入碘不足造成一系列损害,主要表现为甲状腺肿大、克汀病、聋、哑、瘫痪,而其最主要的危害是影响胎儿的大脑发育,导致儿童智力和体格发育障碍,造成碘缺乏地区人口的智能损害。尿碘含量是反映人体碘营养状况最敏

目的:在经济较发达地区基层疾病预防控制机构工作经费相对保障条件下,探索用项目管理式服务外包解决工作任务日益繁重与人力资源不能满足工作需要的矛盾。方法:将疾病预防控制中的部分工作,实行项目管理式服务外包。结果:项目外包对缓解基层疾病预防控制机构人力资源不足、提高工作质量、工作效率与服务水平,降低工作成本发挥了积极的作用。结论:在专业技术要求不强的部分疾病预防控制工作中,可以实行推广项目管理式服务外包模式。

110 children who were given the complete course of the inactivated hepatitis A vaccine (Havrix™) were followed up 10 years later. Age-matched healthy children who were not inoculated served as controls. One month after two primary injections, all children were positive for serum antibody. After 10 years, 99.09% of inoculated children remained positive for serum anti-HAV antibody, with a geometric mean concentration (GMC) of 61.59mIU/mL. GMC values following a secondary immunization in children with antibody levels <20mIU/mL were significantly elevated (567.9mIU/mL), compared with the primary injection alone. Havrix™ appears to induce persistent immunity and potent immune memory.

<正>随着经济社会体制发生的深刻变革,卫生事业得到了很大发展,人民群众的健康水平不断提高。但是,一些传染病、食物中毒等突发公共卫生事件时有发生,对人民群众的身体健康、经济社会发展

目的了解街头暗娼艾滋病/性病感染情况、危险行为以及影响因素,以提供针对性的干预措施。方法对111名街头暗娼进行问卷调查,同时采集宫颈口分泌物、血液进行艾滋病、性病检测。结果街头暗娼性病感染率为6.31%;平均年龄29.63岁,20~40岁占72.08%;初中以下文化占92.79%;有配偶的占69.37%;第一次发生商业性性行为的平均年龄为24.38岁,30岁以内占85.59%;最近1个月发生商业性性行为时每次都使用安全套的占52.25%;顾客不愿意使用安全套时坚决不进行商业性性交易的占26.13%;最近1年内出现性病相关症状的占13.51%,到综合性公立医疗机构就诊占66.67%;最希望得到干预服务的为免费发放安全套和同伴教育。结论本次调查街头暗娼艾滋病性病感染率相对较低,艾滋病性病传播与预防知识知晓率较高,这可能与我区历经三年多的省级艾滋病性病综合防治示范区建设有关。但安全套行动、以同伴教育为主的健康教育、知识咨询等综合性干预措施尚需进一步强化,并可以考虑定期对街头暗娼开展艾滋病/性病感染体检工作。

<正>生命统计是反映一个地区卫生保健工作、居民健康水平和卫生状况的重要指标,分析一个地区的居民病伤死亡状况可为该地制定卫生政策、规划提供重要的科学依据。现就宁波市镇海区2005～2007年居民主要死因之一的恶性肿瘤进行分析。

[目的]为评价迪庆州各县疾控中心结核病实验室对痰涂片制作的质量和镜检能力,提高结核病实验室痰涂片镜检质量.[方法]按照<中国结核病防治规划痰涂片质量保证手册>的要求,采用盲法复检痰涂片.2005年以来坚持每年每季度对各县疾控中心进行一次痰涂片室间质控.[结果]2007年度抗酸杆菌阳性片符合率93.3%,阴性片符合率98.9%,痰细胞符合率96.3%.厚薄合格率95.8%,涂抹大小符合95.4%,染色合格率94.9%,痰膜脱落合格率均为98.6%.[结论]迪庆州结核病痰涂片镜下观察和肉眼观察质量符合国家质量控制标准.盲法复检痰涂片室间质控更具有科学性.

<正>随着改革开放的不断深入,人口流动日趋频繁,尤其是地处沿海的经济发达地区,大量的内地人群纷纷流入,这些人群为了求租廉价的住舍,往往集居在农村和郊区,居舍大多简陋,缺乏户厕等卫生设施,给农村环境卫生带来很大的

土源性线虫中的蛔虫、钩虫、鞭虫、蛲虫是最常见的人体寄生虫.为探索土源性线虫病综合防制措施,我们于1997年开始,历时8年进行了此项研究,现将结果报告如下.

根据<浙江省计划免疫接种门诊规范化建设实施细则>和<宁波市规范化接种门诊评审标准说明(试行稿)>有关精神,我区于1999年开始创建规范化接种门诊工作以来至2000年底已有4家示范接种门诊,1家合格接种门诊,创建率达到50%,现报告如下.

Since 1994,in Jiangbei and Zhenghai districts of Ningbo City,one boosting dose of hepatitis B(HB) vaccine had been generally given to 5-year-old children for 6 years.For evaluating the efficacy of boosting of HB vaccine,using random cluster-sampling method,we selected 901 children born in 1989-1998 in the above mentioned two districts and 398 children unboosted in Ninghai county as well.Blood samples were collected for HBsAg,anti-HBs and anti-HBc detection.The results showed that the anti-HBs positive rate in 5-6 year old children (1-2 years ofter boosting) was much more higher(89.90% and 83.33%) than that in unboosted children of the same age (65.22% and 61.22%).But along with the age growing,the anti-HBs positive rate declined continuously,at the age of 10,anti-HBs positive rate in the former was 67.01%,in the latter was 53.38%.The GMT of anti-HBs was 71.79mIU/ml 2 years after boosting,it decreased to 45.00mIU/ml after 6 years.In unboosted children,it continuously declined to a level of 26.97 mIU/ml at the tenth year of basic immunization.Positive rate of HBsAg and anti-HBc had no significant difference between boosted and unboosted children.It is thus clear,the boosting dose of HB vaccine to 5-year-old children though could raise anti-HBs at a total level in a short time and sustained but it had no preventive effect on hepatitis B virus infection.So,we hold that within 10 years of basic HB immunization,it is not necessary to give boosting dose,since that is not a suitable way of doing.

压力蒸气灭菌法是目前各级医院为防止医源性交叉感染,切断传播途径所采取的重要消毒措施.灭菌效果必须要达到"GB15981-1995消毒与灭菌效果的评价方法与标准",对杜绝医源性感染事故,特别是外科手术等医疗过程中有着非常重要的意义.

托幼机构的消毒管理工作多年来一直未列入卫生防疫工作范畴,自从托幼机构消毒监测工作列入到等级站考核指标以来,各地陆续开始加强了托幼机构的消毒工作管理.这是一个全新的领域,碰到的问题也较多,现结合本地区有关工作开展情况,发表一些想法.

宁波市镇海区根据"中国2000年消除碘缺乏病规划纲要"和"碘缺乏病消除标准"以及"浙江省碘缺乏病防治监测方案",5年来在政府领导协调下,各有关部门的共同努力和群众广泛参与,消除碘缺乏病的工作机制和群众性活动已有组织有步骤展开,取得了显著成绩,1999年11月通过了省、部级考核,达到消除碘缺乏病阶段目标评估要求.现将近几年工作情况与思考总结于下.