目的 探讨团体心理治疗对恢复期精神分裂症患者生活质量及社会功能的影响.方法 选择120例住院的恢复期精神分裂症患者,采用随机数字法分为研究组和对照组.研究组在服用原有药物的基础上额外给予连续12次团体心理治疗;对照组除没有接受团体治疗外,其它条件与研究组相同,观察为期12周.在入组时及12周末分别对研究组和对照组进行精神分裂症患者生活质量量表(SQLS)、个体和社会功能量表(PSP)的评估.结果 治疗12周末两组患者生活质量量表得分明显低于基线水平(33.85±6.80 vs 51.22±5.60,44.26±7.17vs 52.41±5.80,P＜0.05),研究组显著低于对照组(33.85±6.80 vs44.26±7.17,P＜0.001);两组患者社会功能量表得分高于基线水平(56.58±4.35vs50.25±3.50,53.23±3.52 vs 50.10±3.67,P＜0.05),研究组显著高于对照组(56.58±4.35vs53.23±3.52,P＜0.001).结论 对恢复期精神分裂症患者给予团体心理治疗,可以提高患者生活质量,促进其社会功能的康复,帮助患者更好地适应社会.

Objective:To discuss the efficacy of Bromocriptine in treatment of hyperprolactinemia cause by Risperidone and an-alyze the possibility of psychiatric symptom fluctuation for female patients with schizophrenia. Methods:According to the ICD-10, 59 female inpatients diagnosed as schizophrenia and got the mild hyperprolactinemia (100ug/ L<prolactin<200ug/ L) after the treatment with single Risperidone, when their statuses were improved, were treated with Bromocriptine at 5mg/ d, and their serum prolactin levels were reexamined four weeks after the treatment. All the inpatients were asked to finish the brief psychiatric reacting scale (BPRS) be-fore and 2 and 4 weeks after the treatment to test the correlation between the psychiatric symptom and the efficacy of Risperidone com-bined with Bromocriptine. Results: The effective rate of Bromocriptine in the treatment of hyperprolactinemia was 98. 33% (after the treatment, the prolactin level of less than 100μg/ L was valid). There were significant differences by using Bromocriptines (t=22. 166>t0. 001(59), P<0. 001). There were not significant differences in BPRS scores. Conclusions: The clinical study verifies that Bro-mocriptine in the treatment of moderate hyperprolactinemia caused by Risperidone has practical clinical values and reliable efficacy and safety.

<正>1资料与方法1.1样本来源选择2010年4月—2011年4月在本医院住院的女性精神分裂症患者30例,平均年龄(46.0±5.5)岁。所有入组的患者均给予溴隐亭5mg.d-1治疗利培酮所致的高催乳素血症,4周后对所有样本复测血清催乳素(PRL)水平。所有研究对象在入组第0、2及4周分别完成一次18项简精神病反应(BPRS)量表评分,由2名主治医师完成,并对

<正>1病例病例1:患者,女性,26岁。诊断:精神分裂症。入院时查血催乳素:30μg/L。给予利培酮治疗,1周后增至6mg/d,2周后精神症状得以控制,服药30d左右时,患者出现抑郁情绪,感觉活着没有意思。查血催乳素235μg/L;简明精神

<正>2005年5月至2007年5月,我们观察了67例住院精神分裂症患者,发现其中36例空腹胰岛素水平低于正常,而餐后2h胰岛素水平达到或超过空腹胰岛素水平的5～10倍。为探究原因,我们将其与未曾诊断合并糖尿病的非精神分裂症患者74例做对照,并对两组患者各项指标进行了统计分析,报告如下。

目的本文对286例精神病人心电图进行了动态观察,其中男134例,女152例.方法本取样病人均为服用抗精神病药前心电图检查正常的病人,服药后每月复查心电图1次,服药时间不少于5个月.结果与结论心电图异常率女性高于男性(x2=7.3577,P＜0.01,有显著性差异),但男性和女性心电图改变与服用抗精神病药剂量关系不大(x2=0.033,P＞0.05无显著差异).