妊娠期间,羊水量超过2000ml者称羊水过多(polyhydramnios)。发生率为0.5%~1.6%。如羊水量增加缓慢,数周内形成羊水过多者,往往症状轻微,称慢性羊水过多;若羊水在数日内迅速增加,压迫症状严重,称为急性羊水过多。
Objective Subject Discussion the expression of hypoxia inducible factor-1α (HIF-1α) and vascular endothelial growth factor (VEGF) in the case of patients with missed abortion. Method 80 patients in the Daqing Longnan Hospital from January 2012 to December 2013 were dividerd into 2 groups:,the missed abortion, the control group,consisted of 40 patients with unplanned pregnancy and planed to conduct abortion. The villi groups of all patients were first taken after dilatation and curettage and then immunohistochemical staining, lastly, compared its expressions of HIF-1α and VEGF in the two groups. Results The expressions of HIF-1α and VEGF in missed abortion group were 7 cases (17.5%), 28 cases (70%). The expressions in the control group were 24 cases (60%), 40 cases (100%), the expressions of HIF-1αand VEGF cases of missed abortion group was significantly lower than the control group,with statistical significance. (χ2=20.43,P<0.01;χ2= 50.82,P<0.01). Conclusions The low expression of HIF-1α and VEGF may be related to the occurrence of missed abortion.
贫血是妊娠期最常见的合并症。由于妊娠期血容量增加,且血浆增加多于红细胞增加,致使血液稀释。关于妊娠期贫血的诊断国内外有一定的差别,世界卫生组织规定孕妇外周血血红蛋白<110g/L及血细胞比容<0.33为妊娠期贫血。我国多年来一直沿用的标准是血红蛋白<100g/L、红细胞计数<3.5×1012/L或血细胞比容<0.30。最近W H O资料表明,50%以上孕妇合并贫血,以缺铁性贫血最常见,巨幼红细胞性贫血较少见,再生障碍性贫血更少见。
Objective Subject To explore metastasis associated gene 1 (MTA1) and midkine(MK) expression in cervical cancer tissue. Method from 55 cases of cervical cancer respectively stage IA2, IB1 and IIA1 January 2012 to December 2013 in the Daqing Long Nan Hospital were included. Immunohistochemistry was used to detect cervical lesions and tissue expressions of MTA1.and MK and the histological type, depth of invasion, histological grade, lymph node metastasis and cancer tissue vascular invasion of expression were compared. Results 1. There were no significant differences in the expression of MTA1 (69.77% vs 58.33%) and MK (90.70% vs 66.67%) cervical squamous cell carcinoma and adenocarcinoma. (χ2=0.16,P=0.69;χ2=2.64,P=0.10); 2 MTA1 and MK in the depth of invasion ≤1/2 expression (48.39% and 33.33%) was significantly lower than that in the depth of invasion>1/2(χ2=5.60,P=0.02;χ2=14.05,P<0.01)3. In pathological grading, the expression of MTA1 and MK in that were G1 (83.33%and 100%) significantly lower than in the G2-G3 (51.28%and 71.79%)(χ2=4.94,P=0.03;χ2=5.65,P=0.02).4. Comparison of lymph node metastasis, lymph node metastasis MK and MTA1 expression (86.96%and 95.65%) was significantly higher than those without lymph node metastasis (50% vs 65.63%).(χ2=8.08,P<0.01;χ2=5.42,P=0.02)5. Comparison of vascular invasion, the expression of vascular invasion were significantly higher than MTA1 (90.48%vs 52.94%) and MK (95.24%vs 44.12%) were no vascular invasion.(χ2=8.31,P<0.01;χ2=12.53,P<0.01). Conclusions Abnormal expression of MTA1 and MK may be involved in the development of cervical cancer.
妊娠期间各种内分泌腺处于活跃状态,各器官系统均会发生一系列的生理变化,对甲状腺功能均会产生直接或间接的影响。妊娠合并甲亢较非孕期难以诊断,治疗上亦涉及母体与胎儿的特殊情况,与非孕期不尽相同。
宫口开全后,胎膜多已自然破裂。若仍未破裂,常影响胎头下降,应行人工破膜。破膜后,宫缩常暂时停止,产妇略感舒适,随后宫缩较前增强,每次持续1分钟或更长,间歇1~2分钟。当胎头下降压迫盆底组织时,产妇有排便感,并不自主地产生向下用力屏气的动作;会阴膨隆和变薄,肛门括约肌松弛。胎头于宫缩时露出于阴道口,在宫缩间歇期胎头又回缩至阴道内,称胎头拨露;宫缩间歇期胎头也不再回缩,称胎头着冠[1]。产程继续进展,胎头娩出,接着出现胎头复位及外转旋,随后前肩和后肩相继娩出,胎体很快娩出,后羊水随之涌出经产妇第二产程短,有时仅需几次宫缩即可完成胎头娩出。
目的:正确处理产程,防止产程延长,以保证母婴健康,降低围生儿病残率,提高新世纪出生人口素质。方法:收集30例住院分娩的初产妇,排除患其他系统疾病者。根据产程进展过程中出现的不同情况进行不同的处理。结果:30例初产妇,阴道自然分娩24例,经阴道助产分娩2例,剖宫产4例。母婴均健康。结论:产程延长不但对新生儿健康不利,也对产妇的健康构成重大威胁。正确处理产程,防止产程延长是保证母婴健康的重要手段。
目的:研究光量子自血疗法,对急性脑梗死的疗效.方法:选择本院2007年9月~2008年10月住院的急性脑梗死患者65例,随机分为对照组和治疗组,观察治疗前后血流动力学指标及神经功能缺损评分的变化.结果:治疗组治疗后与治疗前比较,血流动力学中的全血黏度低切、全血黏度高切、红细胞刚性指数、血浆纤维蛋白原均下降(P<0.05),临床神经功能缺损程度减轻(P<0.05),未发现不良反应.结论:光量子自血疗法可改善脑梗死患者血流动力学的情况,尤其是降低血液黏度,增强红细胞变形能力,使临床症状得到明显改善,其治疗效果安全可靠.
目的:正确处理产程,防止产程延长,以保证母婴健康,降低围生儿病残率,提高新世纪出生人口素质.方法:收集30例住院分娩的初产妇.排除患其他系统疾病者.根据产程进展过程中出现的不同情况进行不同的处理.结果:30例初产妇.阴道自然分娩24例,经阴道助产分娩2例,剖宫产4例.母婴均健康.结论:产程延长不但对新生儿健康不利,也对产妇的健康构成重大威胁.正确处理产程,防止产程延长是保证母婴健康的重要手段.