目的 分析通降舒膈汤治疗胃食管反流病肝胃不和证的临床效果.方法 选取2016年5月～2017年12月期间来院进行诊治的胃食管反流病肝胃不和证患者80例作为研究对象开展对比研究.将80例患者基于随机数字表法分为对照组和试验组,每组40例,给予对照组患者雷贝拉唑钠肠溶片联合莫沙必利进行治疗,试验组患者在雷贝拉唑钠肠溶片联合莫沙必利治疗的基础上采用通降舒膈汤进行治疗,观察两组患者的治疗效果、疾病复发率以及治疗前后的胃食管反流病调查评分量表(GERD-Q)评分情况.结果 试验组患者的治疗总有效率为97.50％(39/40),对照组患者的治疗总有效率为87.50％(35/40),差异具有统计学意义(P<0.05);试验组患者治疗后2周以及治疗后4周的疾病复发率分别为5.00％(2/40)和7.50％(3/40),对照组患者治疗后2周以及治疗后4周的疾病复发率分别为17.50％(7/40)和22.50％(9/40),差异均具有统计学意义(P<0.05).治疗前试验组和对照组患者的GERD-Q评分分别为(11.38±2.47)和(11.54±2.64),差异无统计学意义(P>0.05),治疗后试验组和对照组患者的GERD-Q评分分别为(5.46±1.23)和(7.58±1.53),差异具有统计学意义(P<0.05).结论 对于胃食管反流病肝胃不和证患者采用通降舒膈汤进行治疗可以有效提高患者的治疗效果,降低患者的疾病复发率,明显改善患者的GERD-Q评分.

慢性咽喉炎是常见耳鼻喉科疾病,该病主要临床症状为咽部异物感、咽喉疼痛、干涩等[1].该病在治疗上较为棘手,不仅病程长,还易反复发作,影响患者正常生活与工作.常规西药治疗仅能短时间内缓解症状,若想达到良好的预后,还需要中医学治疗的帮助[2].在我国医学理念中,认为脾胃失和是导致该病的重要原因之一,因此调节脾胃是治疗关键.本研究重点分析中医脾胃论疗法对慢性咽喉炎的临床治疗效果.

目的 探讨甘草酸铋散联合泮托拉唑钠肠溶片治疗十二指肠溃疡的临床疗效.方法 选取2018年2月-2019年2月在天津市西青医院治疗的十二指肠溃疡患者88例,按照治疗方法的差别分为对照组(44例)和治疗组(44例).对照组口服泮托拉唑钠肠溶片,40 mg/次,1次/d;治疗组在对照组基础上口服甘草酸铋散,1 g/次,3次/d.两组患者经4周治疗.观察两组患者临床疗效,同时比较治疗前后两组患者症候积分、血清白细胞介素-1β(IL-1β)、白细胞介素-18(IL-18)、白细胞介素-23(IL-23)、血管内皮生长因子(VEGF)、高迁移率族蛋白1(HMGB1)、前列腺素E2(PGE2)、肾上腺髓质素(AM)、胃泌素(GAS)、生长抑素(SS)和降钙素基因相关肽水平(CGRP)水平,及GQOL-74量表评分.结果 治疗后,对照组和治疗组临床有效率分别为81.82％和97.73％,两组比较差异有统计学意义(P<0.05).治疗后,两组患者症候积分显著下降(P<0.05),且治疗组患者这些症候积分明显低于对照组(P<0.05).治疗后,两组患者血清AM、GAS、IL-1β、IL-8、IL-23和HMGB1水平水平均明显下降(P<0.05),而CGRP、SS、VEGF和PGE2水平均明显升高(P<0.05),且治疗组患者这些细胞因子水平明显好于对照组(P<0.05).治疗后,两组患者GQOL-74量表评分均明显升高(P<0.05),且治疗组患者GQOL-74量表评分明显高于对照组(P<0.05).结论 甘草酸铋散联合泮托拉唑钠肠溶片治疗十二指肠溃疡可有效改善患者临床症状,降低机体炎症反应,促进溃疡愈合.

目的:对黄芪建中汤合理中汤治疗脾胃虚寒型慢性胃炎的临床疗效进行探讨.方法:将2016年11月～2018年1月到我院接受治疗的60例脾胃虚寒型慢性胃炎患者选取为研究对象,根据所使用的治疗药物不同,将其分为西药组和中药组,每组均为30例,西药组患者采用奥美拉唑肠溶胶囊进行治疗,中药组患者则采用黄芪建中汤合理中汤进行治疗,之后再对比两组患者的临床治疗效果.结果:西药组的治疗有效率明显低于中药组,差异具备统计学意义(P＜0.05).结论:黄芪建中汤合理中汤可以使脾胃虚寒型慢性胃炎患者的临床症状得到有效的改善,对于促进患者早日康复具有重要的意义,值得推广采用.

【Objective】 By comparing the benefit-risk ratioin patients with deep venous thrombosis(DVT),continued to be treated with low molecule weight heparin(LMWH) or vitamin K antagonists(VKA),to explore the more effective,safe and convenient therapeutic regimen.【Methods】 Patients fit the standard in this study from December 2008 to March 2011 were randomly divided into two groups.Patients in Group A were treated with Low-molecular-weight heparins calcium injection,and Warfarin in Group B.A follow-up visit was perpormed every two months for half a year,the content including whether there was bleed,heparin-induced thrombocytopenia(HIT),and the recrudescence event occurs,in this period hemoglutination function and platelet count were monitored regularly,and according to the date to make adjustment in medication plan.【Results】 Effective anticoagulation was obtained in the two groups,and the incidence rate of side effect in group A was lower than that in group B obviously(P0.05).There was no difference about the rate of recrudescence in DVT(P0.05),but along with the anticoagulant time expand,the hemorrhage rate increasedin the two groups.However,in the DVT recrudescence patient.The rate in ilio-femoral vein was the highest,next was femoral vein,and finally was popliteal vein.Patient treated with LMWH revealed a better compliance.【Conclusion】 Using LWMH for patients with DVT outside hospital continuely revealed reliable result and high medication security,low side effect,simple operation and monitor,so it is better in benefit-risk than using VKA.

【Objective】By comparing the curative effect and adverse events in treating calcanodynia by fumigation with Traditional Chinese Medicine and local blocking respectively,to explore the effective and convenient therapeutic treatment modality.【Methods】 130 cases of calcanodynia were randomily divided into two groups 65 in each.Cases of Group A were treated by fumigation with Traditional Chinese Medicine,and local blocking in Group B.Curative effect and adverse events were recorded and analyzed.【Results】There were no significant different in Group A and Group B on the effective rate of treatment(P 0.05).In group A,drug allergy was observed in 2 cases and mildly scalded in 3.In group B,incision infection was observed in 2 cases,hypodermic gore in 6 and subcutaneous nodules formation in 3.The statistical results show that the percentage of adverse events in group A was lower than that of group B(P 0.05).【Conclusion】The modality was effective,simple and dependable in treating calcanodynia with fumigation with Traditional Chinese Medicine.