本文运用描述性统计法和交叉统计法对长三角皮肤病专科联盟同质化建设的现状进行分析,旨在为探索皮肤病专科医联体建设提供参考.

目的 评价刺络拔罐治疗斑块型银屑病血瘀证的临床疗效及安全性.方法 73例斑块型银屑病血瘀证患者,随机分入刺络拔罐组(37例)和卡泊三醇软膏组(36例).观察2组患者治疗前后的临床疗效,以及银屑病皮损红斑、浸润、脱屑的症状评分,并分析不良反应.结果 2组患者治疗前后银屑病皮损面积及严重程度指数(PASI)评分的差异均有统计学意义(P<0.05).治疗第4周治疗组患者的PASI评分低于对照组,差异有统计学意义(P<0.05).2组患者红斑和脱屑评分在治疗前后比较差异有统计学意义(P<0.05),治疗第4周治疗组对红斑评分的改善较对照组更为明显,而对照组对脱屑评分的改善较治疗组更为显著.治疗第4周,治疗组有效率为94.59％,对照组有效率为77.78％,差异有统计学意义(χ2=4.365,P<0.05).结论 刺络拔罐治疗斑块型银屑病血瘀证的疗效好,安全性高.

目的 评价连柏祛银方外洗治疗血热证头部银屑病的疗效及安全性.方法 60例血热证头皮银屑病患者,随机分入连柏祛银方观察组和卡泊三醇捈剂对照组(每组30例).观察2组患者治疗前后的临床疗效、头皮银屑病皮损面积及严重程度指数(PSSI),并分析不良反应发生情况.结果 2组患者治疗前及治疗第2周PSSI评分差异无统计学意义(P＞0.05);治疗第4周观察组患者的PSSI评分低于对照组,差异有统计学意义(P＜0.05);2组患者PSSI评分较治疗前均有所改善(F=254.192,P＜0.05);2组患者PSSI评分的改善趋势随着治疗时间的增加而不同(肚4.81,P＜0.05),其中观察组改善趋势较对照组更为明显;治疗第2周观察组有效率为80％,对照组有效率为70％,2组比较差异无统计学意义(x2=0.80,P＞0.05);治疗第4周,观察组有效率为96.67％,对照组有效率为76.67％,差异有统计学意义(x2=5.19,P＜0.05).结论 连柏祛银方外洗治疗血热证头皮银屑病疗效好,安全性高.

[Objective] To evaluate the quality of life in cases of alopecia areata and explore its influence factors. [Methods] Questionnaires were done in 107 cases of alopecia areata and 102 control cases with DLQI and SF-36. [Results] The DLQI scores in alopecia group were higher than those in the control group(P<0.05).The SF-36 scores in alopecia group were lower than those in the control group(P<0.05).Vitality,social function and emotional function may influence the result.Stepwise regression analysis showed duration of disease,hair loss area and the recurrence was statistically significant in the regression equation,with positive correlation with DLQI and negative correlation with SF-36. [Conclusion] Alopecia areata reduces the quality of life.Early treatments are essential for relieving patients from psychologically devastating effects.The DLQI and SF-36 are good evaluation methods for evaluation of quality of life in cases of alopecia areata..As the duration is longer,the area of hair loss becomes larger,DLQI in recurrent cases is higher and SF-36 lower,that is,the quality of life is worse.