Objective To explore the effect of depression on loneliness in medical students',and the mediating effects of introverted personality and social support.Methods EPQ,UCLA,SSRS,and POMS questionnaire were used,and surveyed data was collected from Dalian Medical University medical students.Results The scores of depressive mood,introverted personality,social support and loneliness were (17.77±4.45),(11.97±5.21),(34.52±6.15) and (38.02±6.36).Depression was positively related to loneliness and introverted personality (r=0.286,0.508,P＜0.01),and social support was negatively related to loneliness (r =-0.443,P＜0.01).Introverted personality was positively related to loneliness(r=0.401,P＜0.01).The total effect value was 0.670.The mediating effect of introversion as mediator variable was 0.221,accounting for 33％ of the total effect.Social support as intermediary variable,intermediary effect value was 0.449,accounting for 67％ of the total effect.Standard value of mediating effect between depression and introverted personality showed as 0.508 (95％CI=0.475-0.725,P＜0.0i),standard value of mediating effect between depression and social support showed as-0.150 (95％CI=0.989-1.469,P＜0.01),introverted personality was the mediating variant of depression and loneliness,standard value of mediating effect was 0.156 (95％ CI=0.080-0.232,P＜0.01),social support was the mediating variant of depression and loneliness,standard value of mediating effect was 0.317 (95％ CI=0.177-0.457,P＜0.01).Conclusions Introverted personality and social support play an intermediary role between depression and loneliness.

目的 观察全程健康教育模式在溃疡性结肠炎患者中应用的效果,评价其临床应用护理管理价值.方法 选取大连大学附属新华医院消化内科2012年3月至2015年6月医治的86例溃疡性结肠炎患者为研究对象,随机分为对照组(常规护理管理)与观察组(全程健康教育管理),通过护理干预,对比两组护理满意度、不良事件发生的情况.结果 观察组治疗总有效率为90.70%,显著高于对照组的41.86%(P<0.05),经过护理管理后,观察组总满意度(93.02%)明显优于对照组86.04%(P<0.05);UC患者出现不良事件、出院后的随访自我评价(1月、2月),观察组优于对照组(P<0.05).结论 全程健康教育管理对患者进行护理干预,提升了患者对病情的认知度、依从性,提高了临床疗效、护理满意度,对临床路径的程序制定也具有指导意义.