通过给人工感染多杀性巴氏杆菌的鸡饲喂含药物的饲料,观察中药五倍子、恩诺沙星,以及五倍子与恩诺沙星联合使用对鸡巴氏杆菌病的防治效果。结果表明,治疗组和预防组的死亡率较对照组降低,预防组的死亡率明显低于治疗组;恩诺沙星对鸡巴氏杆菌病的治疗及预防效果较好,存活率显著高于对照组(P<0.05),保护率分别为33.33%和70%;五倍子与恩诺沙星联合使用对鸡巴氏杆菌病的治疗及预防效果不明显,保护率分别为11.11%和40%。尽管中西药联合体外抑菌效果显著,对动物疾病的防治效果不一定明显。

The experiment was aimed to investigate the effects of ciprofloxacin(CIP) on number and resistance of bacteria isolated from soil.After the soils were treated with CIP for 35 days,bacteria isolated from soil samples by culturing on isolation media were counted,and the antimicrobial susceptibilities of soil bacteria were examined to study the effect of CIP on soil bacteria.The results showed that the counts of soil bacteria were different among 6 treatment groups.The total bacteria counts of treated groups were less than those of CK,and they were decreased with the increasing concentration of CIP in soil.The susceptibilities of CIP-sensitive bacteria to 12 kinds of antimicrobial agents among 20 kinds of antimicrobial agents were not significantly distinguished from that of CIP-resistant bacteria(P>0.05).

Abstract： The experiment was aimed to investigate the effects of NOR （norfloxacin） on the quantity and dnlg-resistanee of bacteria isolated from soil. After the soils were treated with NOR for 35 days, bacteria isolated from soil samples were cultured on isolation media, and their antimicrobial susceptibilities were examined to study the effect of NOR onsoilbaeteria. The： resutts sh0wCd that the counts of soil among 6 treatment groups. The total bacteri; counts of treated groups were less than those of CK, and they were decreased with the increasing c0ncentration of NOR i, soil. The susceptlbiltles of NOR2sensltive bacteria to 18 kinds bf antimicrobial agents among 20 kinds of antiseptic wet, not significantly distinguished from that of NOR＇resistant bacteria （p〉0.05）