目的 探讨肺泡微石症在多层螺旋CT中的特征表现.方法 对6例肺泡微石症患者行胸部X线检查及多层螺旋CT检查,并对全部影像学表现进行回顾性分析.结果 6例患者病灶呈弥漫或较广泛分布,双肺大致对称,病变从上到下逐渐增多,其中以右肺中叶、下叶,尤其是心缘旁及肺后部、叶间胸膜、支气管血管束周围密集.MSCT征象及其表现呈小结节状钙化影、线状钙化影、火焰状钙化影、黑胸膜线影.结论 肺泡微石症是一种少见病,其多层螺旋CT表现具有特征性,在本病的诊断与鉴别诊断中起决定性作用.
Objective To discuss the influences of mycobacterium vaccae (M.vaccae) on the level of peripheral blood T lymphocytes in tuberculosilicosis patients,and to offer an immune adjuvant therapy for these patients.Methods Silicotuberculosis patients were randomly divided into M.vaccae use group (treatment group) and non-use group (control group) by age and disease stage.M.vaccae were deeply injected into hip muscle at the dose of 22.5 μg/time once two weeks in the treatment group.The control patients were treated with the same TB chemotherapy but not M.vaccae.T lymphocytes were analysed at the time of pre-treatment,1,2 and 4 months after M.vaccae usage.Results CD3,CD4 levels in the treatment group of 4-month M.vaccae usage were significantly higher (P0.05) than those of the control group.And the CD3,CD4 averages were gradually increased following the time of M.vaccae usage (P0.01 or 0.05) in treatment group between pre-and post-treatment.Average immunization indicators recovered to normal levels at the 4 months of M.vaccae usage.In addition,CD3,CD4 and CD8 abnormal rates (%) were decreased following the time of treatment in treatment group(P0.05).The absorption rate of tuberculosis infiltration was significantly higher than that of the control group(P0.05).Conclusion T lymphocyte levels can be increased by the use of M.vaccae in patients with tuberculosilicosis,and the use of M.vaccae also promotes the absorption of tuberculosis infiltration,so it can be used as immune adjuvant therapy for patients with tuberculosilicosis.