To review the clinical data of 13 patients with benign stenosis in deep small intestine treated by balloon-assisted enteroscopy from September 2017 to December 2019, and to evaluate the stenosis characteristics, endoscopic treatment effects and its safety in different lesions. The results showed that there were 6 cases of Crohn disease (CD), 4 cases of cryptogenic multifocal ulcerative stenosing enteritis (CMUSE) and 3 cases of small bowel stenosis with unknown etiology. A total of 38 stenoses were found after 17 enteroscopic treatments, including 35 web-like stenoses and 3 columnar stenoses. Thirteen stenoses were found in 6 patients with CD, including 4 single stenosis, 1 case of 3 stenoses and 1 case of 6 stenoses. Twenty-one stenoses were found in 4 patients with CMUSE and they were all web-like stenosis. A total of 18 times of balloon dilatation and 10 times of IT knife incision were performed. The technical success rate was 88.2% (15/17), and the clinical effective rate was 76.9% (10/13). The follow-up time was 3-28 months, and one patient underwent surgical treatment. There was 1 case of delayed hemorrhage and 3 cases of delayed perforation after operation. They were all improved by medical treatment. These results indicated that treatment of benign stenosis in deep small intestine by enteroscopy is technically feasible and can improve the symptoms of patients in a short time.
Objective:To study clinical efficacy of Bismuth-containing quadruple therapy in patients with chronic gastric ulcer and Helicobacter pylori (H. pylori) infection.Methods:A total of 117 patients with chronic gastric ulcer and H pylori infection treated in Xuancheng People’s Hospital between June 2015 and June 2019 were divided into group A ( n=39) , group B ( n=35) and group C ( n=43) based on random number table. Group A was given Rabeprazole (10 mg, bid) , sustained released Clarithromycin capsules (1.0 g, qd) , Amoxicillin (1.0 g, bid) and Colloidal Bismuth Pectin (H20064288, 200 mg, bid) , for a treatment course of 10 days. In addition to the care given in group A, the group B was given a higher dose of Rabeprazole (20 mg, bid) , and the treatment course in group C was extended to 14 days. The H. pylori eradication by intention-to-treat (ITT) and per-protocol (PP) analyses, and symptom relief were compared among three groups. Analysis on cost-effectiveness was conducted, and the incidence of adverse reactions recorded. Results:(1) There was no significant difference in negativity rate by 14C-UBT review, outcome of ITT or PP analysis among three groups ( P>0.05) . (2) After treatment, the symptom scores and diameter of gastric ulcer within each of the three groups were significantly decreased, with no statistical differences among groups. (3) The ratios of cost-effectiveness with the three preparations were 2.16, 2.88 and 2.69, respectively. (4) There was no significant difference in incidence of adverse reactions among the three groups ( P>0.05) . Conclusion:For chronic gastric ulcer accompanied by H. pylori infection, bismuth-containing quadruple therapy is therapeutically reliable and satisfactorily safe. Standard dosage of Rabeprazole is therapeutically comparable to double-dose Rabeprazole. Extending the treatment course of Rabeprazole does not lead to a significant difference in treatment efficacy. These findings are of clinical implications.
内科比较常见的疾病就是消化道疾病,患者主要表现为肚痛,腹胀,消化不良等,当患者出现消化内科的问题时,应该尽快到医院检查.胃肠镜是临床上诊断胃肠道疾病的金标准,可以快速清晰的显示胃肠道的病变和病灶,有助于做出正确的诊断和治疗方案,因此称为消化道的保护神.无痛胃肠镜是一种新型的无痛的胃肠检查技术,在临床上效果显著,本文就无痛胃肠镜在消化内科临床中应用进行研究分析.
目的:探讨急诊内镜消化道异物取出术的有效方法。方法:回顾性探讨我院2007年8月~2013年8月消化道异物取出术91例,总结分析内镜下消化道异物取出术的成功经验。结果:91例患者经急诊内镜成功取出异物85例,放弃内镜下取出术6例。结论:急诊内镜下消化道异物取出术需要根据异物的性质、部位以及患者的身体状况采取不同的方法。