<正>口腔种植体以其独特的优势(创伤小、形态佳、固定持久等),在种植义齿修复骨折及赝复体固定、颞下颌关节重建等方面起到举足轻重的作用。其关键在于种植后的愈合。目前与口腔种植领域相关的研究聚焦于从生物机械力学、分子生物学、细胞生物
目的 探讨遗传性牙龈纤维瘤病(hereditary gingival fibromatosis,HGF)的临床表型和遗传学特征,并对国外已证实的已知基因突变位点-SOS1基因21号外显子的排除性定位.方法 回顾我院2007年10月收治的1例HGF患者,对其发病机制、临床表现及其相关综合征、遗传学特征、组织病理学表现、诊断分型及治疗预后进行分析.结果 本例患者符合非综合征型HGF.结论 HGF属常染色体显性遗传性疾病,表型多样.
Objective To determine whether there is some relationship between sulcular sulfide level and severity of periodontitis.Methods Fifteen systemically healthy subjects diagnosed with aggressive periodontitis(AgP) and sixteen systemically healthy subjects diagnosed with chronic periodontitis(CP) were included in this study.Clinical periodontal parameters such as plaque index,probing depth,attachment loss,bleeding on probing(BOP) et al,were recorded.The volatile sulphur compounds (VSC) level in periodontal pockets was measured using a portable monitor in a digital score ranging from 0.0 to 5.0 in increments of 0.5.All of 5220 sites for 870 teeth were included in this study.Results For both AgP and CP subjects,the clinical periodontal parameters were found significantly higher in VSC-positive sites than in VSC-negative sites(P0.001).The VSC level has significantly positively correlated with clinical periodontal parameters(P0.001).The VSC level and percentage of VSC-positive sites were found significantly higher in moderate-to-deep pocket sites than in shallow pocket sites(P0.001).The VSC level and percentage of VSC-positive sites were higher in sites with attachment loss than those in sites without attachment loss in the same probing depth group.Conclusion The VSC level may be a potential indicator for detecting severity of both AgP and CP.
