Objective To observe the application effect of psychological intervention in the rehabilitation training of stroke patients with dysphagia. Methods 66 stroke patients with dysphagia treated in our department from January 2019 to December 2020 were selecte

目的:对于小儿哮喘性支气管炎疾病采取孟鲁司特联合布地奈德雾化吸入进行治疗的临床效果开展探讨.方法:选择2018年1月至2020年6月徐州医科大学附属徐州市立医院接诊的小儿哮喘性支气管炎患者60例作为本文观察对象,根据小儿哮喘性支气管炎患者的入院顺序对其开展分组,其中一组小儿哮喘性支气管炎患者接受常规治疗,共计30例纳入到对照组,剩余一组小儿哮喘性支气管炎患者接受孟鲁司特联合布地奈德雾化吸入治疗,共计30例纳入到研究组,对比两组小儿哮喘性支气管炎患者接受不同治疗措施之后的临床效果.结果:研究组与对照组小儿哮喘性支气管炎患者接受不同治疗方案之后的临床总体有效率对比差异明显.结论:临床中针对小儿哮喘性支气管炎患者,为其提供孟鲁司特联合布地奈德雾化吸入治疗效果明显,能够显著改善小儿哮喘性支气管炎患者的肺功能,应该给予大力的推广与应用.

目的 本次研究的目的在于探究脑卒中吞咽障碍患者在治疗中采取间歇经口管饲营养护理疗效.方法 主要运用护理比较的方式来进行本次研究,研究样本数量为60例,样本均为2018年1月至2018年12月期间我科诊治的脑卒中吞咽障碍患者,随机选择其中30例患者进行鼻饲管管饲法护理为对比组,剩下30例患者进行间歇经口管饲营养护理为试验组.结果 试验组患者的吞咽障碍改善程度显著比对比组好,P<0.05.结论 将间歇经口管饲营养护理应用在脑卒中吞咽障碍患者的治疗过程中,可有效帮助患者改善吞咽障碍程度.

目的:探讨容积-黏度吞咽测试(V-VST)在帕金森病(PD)患者吞咽障碍筛查中的应用.方法:选取48例PD吞咽困难患者随机分为观察组和对照组各24例,对照组采用洼田饮水试验进行评估筛查病情,观察组采用V-VST进行评估筛查病情,比较两组临床有效率、进食与吞咽功能.结果:观察组临床总有效率显著高于对照组(P<0.01),观察组禁食、补液、留置胃管均低于对照组(P<0.01);经干预后,两组吞咽功能较干预前显著改善(P<0.05);且观察组吞咽功能优于对照组(P<0.05).结论:将V-VST应用于PD患者吞咽障碍筛查中,能准确提高筛查准确性,降低误吸发生率与留置胃管率.

Objective To analyze the relationship between serum asymmetric dimethylarginine (ADMA) and initial acute coronary syndrome (ACS) after taking a proton pump inhibitor (PPI). Methods From January 2017 to October 2018, we enrolled 140 patients with initial ACS and 70 healthy subjects. Among them, 70 patients were included in a PPI group (administration of PPI+ initial ACS), 70 patients in an ACS group (non-PPI+ initial ACS), and 70 healthy subjects (non-PPI+ non-ACS) in a control group. Serum ADMA concentration was measured by enzyme linked immunosorbent assay, and cholesterol and triglyceride were measured routinely. General demographic information, biochemical indicators, and ADMA levels were compared by one-way ANOVA, nonparametric test, and chi-square test. Mann-Whitney U test was used for comparison between groups. Spearman correlation analysis was used to analyze the relationship between serum ADMA level and traditional risk factors of acute coronary syndrome. Multivariate logistic regression analysis was used to investigate the risk factors for ACS. Results Serum ADMA levels in the PPI group and the ACS group were both significantly higher than that in the control group (Z=-9.585, -4.793, P 0.05). Logistic regression analysis showed that serum ADMA level was an independent risk factor for patients with initial ACS (β=0.017, OR=1.017, P<0.001). Conclusions Serum ADMA levels in patients with initial ACS after taking proton pump inhibitors are significantly higher than those in initial ACS patients without taking proton pump inhibitors. Serum ADMA levels in patients with initial ACS are significantly higher than those in healthy controls. Elevated serum ADMA is an independent risk factor for initial ACS. Key words: Asymmetric dimethylarginine; Proton pump inhibitor; Acute coronary syndrome