Objective:To explore the therapeutic effect of Jianpi Huoxue Jiedu recipe on upper limb edema of spleen deficiency and dampness stagnation, blood stasis and toxin internal knot type after modified radical surgery for breast cancer.Methods:From January 2020 to May 2022, a total of 60 patients with upper limb edema of spleen deficiency and dampness stagnation, blood stasis and toxin internal knot type after modified radical surgery for breast cancer were selected and treated in Longyan Hospital of Traditional Chinese Medicine Affiliated to Xiamen University. They were divided into control group and observation group according to random number table, with 30 cases in each group. The control group was treated with routine western medicine comprehensive swelling reduction surgery, while the observation group was treated with a combination of Jianpi Huoxue Jiedu recipe (1 dose/day, warmly-taken in the morning and evening) for one month on the basis of the control group. The clinical efficacy, traditional Chinese medicine (TCM) syndrome score, edema diameter, breast cancer quality of life scale (FACT), and joint range of motion were compared between the two groups after treatment.Results:After one month of treatment, the total clinical effective rate of the observation group (93.33%) was significantly higher than that of the control group (70.00%, P<0.05). After treatment, the TCM syndrome scores (upper limb swelling, pain, fullness, sense of restraint, skin keratinization, itching, heaviness, stuffiness, and fatigue) of both groups of patients decreased compared to those before treatment, and the observation group was lower than the control group (all P<0.05). After treatment, the diameter of edema in the affected limbs was significantly reduced in both groups of patients, and the diameter of 10 cm above the wrist and elbow stripes in the observation group was smaller than that in the control group (all P<0.05). After treatment, the FACT scores of the two groups of patients significantly decreased, and the FACT scores of the observation group were lower than those of the control group (all P<0.05). After treatment, the joint activity of the two groups of patients significantly increased, and the joint activity of the observation group was greater than that of the control group (all P<0.05). Conclusions:The clinical efficacy of Jianpi Huoxue Jiedu recipe combined with western medicine in treating upper limb edema of spleen deficiency and dampness stagnation, blood stasis and toxin accumulation type after modified radical operation of breast cancer is better than that of western medicine alone. It can significantly improve the clinical symptoms, signs, quality of life, and joint mobility of upper limbs of patients, and reduce upper limb edema.

目的:探讨阳和通络汤对结直肠癌患者化疗后神经毒副反应的影响.方法:选取2020年7月-2021年12月于龙岩市中医院肿瘤科住院的120例结直肠癌患者,采用随机数字表法将其分为治疗组60例与对照组60例.对照组单纯化疗,治疗组在对照组的基础上给予阳和通络汤口服.比较两组外周神经毒性反应分级情况、奥沙利铂专用感觉神经毒性分级情况、中医症候量表评分、生活质量评分和血流动力学指标.结果:治疗后,治疗组外周神经毒性分级和奥沙利铂专用感觉神经毒性分级均优于对照组,且差异均有统计学意义(P<0.05).治疗后,治疗组生活质量评分、中医症候量表评分、血浆黏度、全血低切黏度和全血高切黏度均优于对照组,差异均有统计学意义(P<0.05).结论:阳和通络汤对结直肠癌患者化疗后神经毒副反应的临床治疗效果较好,能够改善外周神经毒性和奥沙利铂专用感觉神经毒性情况,改善患者临床症状、纠正患者血流动力学指标,是临床防治奥沙利铂所致神经毒性的可靠方案之一.

目的:研究和分析肝胆湿热型肝癌恶性腹水患者联合应用茵陈蒿汤、三仁汤及体腔热灌注治疗的效果.方法:选取2018年3月-2021年12月龙岩市中医院收治的62例肝胆湿热型肝癌恶性腹水患者,依照入院时间编号并通过随机数字表法将患者分成对照组与试验组,每组31例.对照组采用体腔热灌注治疗,试验组在对照组的基础上联合应用茵陈蒿汤及三仁汤.比较两组腹水治疗效果、肝癌近期疗效、毒副作用、治疗前后甲胎蛋白(AFP)、糖类抗原125(CA125)水平及治疗前后患者生命质量改善情况.结果:试验组腹水治疗总有效率高于对照组(P<0.05).试验组疾病控制率高于对照组,差异有统计学意义(P<0.05).两组临床有效率比较,差异无统计学意义(P>0.05).治疗前,两组CA125与AFP水平比较,差异均无统计学意义(P>0.05);治疗后,试验组CA125与AFP水平均低于对照组,差异均有统计学意义(P<0.05).治疗前,两组各维度生命质量评分比较,差异均无统计学意义(P>0.05);治疗后,试验组各维度生命质量评分均高于对照组,差异均有统计学意义(P<0.05).两组便秘、腹泻、口腔炎及恶心呕吐发生率比较,差异均无统计学意义(P>0.05),试验组神经毒性、血小板减少、贫血及白细胞减少发生率均低于对照组,差异均有统计学意义(P<0.05).结论:肝胆湿热型肝癌恶性腹水患者联合应用茵陈蒿汤、三仁汤及体腔热灌注治疗能够促进病情缓解,提升患者生命质量,还能够减轻毒副作用,值得应用.