从"阳化气,阴成形"理论入手,探讨调理肝肾对治疗排卵障碍性不孕的意义.认为肝肾二脏功能的不足与太过是致使"阳化气"与"阴成形"平衡失调的关键因素,也是导致排卵障碍性不孕的主要原因."补其不足,损其有余"可恢复"阳化气,阴成形"平衡,是调经、促卵、助孕最有效、最直接的办法.

中医学认为气滞、体虚、外邪、医源性因素是卵巢早衰的主要病因,临床常以活血化瘀为治疗大法,以行气化瘀法、补血活血法、祛邪活血法、缩宫逐瘀法、补肾疏肝法为具体治疗方法,治疗效果亦较明确,并附验案1则.

以既病防变的宏观治病思路深入剖析,探讨其与自噬可能存在微观联系.认为自噬作为一种自我保护性的细胞死亡,对维持细胞及机体内环境稳态具有重要作用.近年来发现自噬水平的高低影响着宫颈癌前病变的发生发展,具有双向调节作用.中医既病防变理论包含了早期治疗及防止传变两层含义,抓住宫颈癌前病变这一黄金期进行调控的思路,与中医"既病防变"理论不谋而合,从中医微观辨证角度探讨,自噬机制与人之"正气"相类,自噬维持的稳态即"阴平阳秘"状态,既病防变理论原则下需要早期扶正制邪及平衡阴阳,防止疾病传变,当下中医药对细胞自噬的调节作用已有一定的实验论证,但证据不够充分,其中的调控机制仍亟待研究.

Autophagy is a self-protection mechanism of the body, and also an important physiological process for cells to maintain internal environment stability. Studies have shown that the degree of autophagy damage is positively correlated with the expression of oncogenes, and the expression of oncogenes is closely related to cervical HPV infection, so the control of autophagy ability can interfere with cervical HPV virus infection. Traditional Chinese medicine believes that dampness-heat evil down, can damage and Chong Ren cell. The author believes that autophagy damage and the theory of dampness-heat injection in cervical HPV infection have similar pathogenic mechanism, and explores the prevention and treatment of autophagy and cervical HPV infection based on the theory of traditional Chinese medicine dampness-heat injection, in attempt to provide a new treatment for clinical prevention and treatment.