The aim of the research. To assess the state of the microcirculation in the lower limbs using transcutaneous oximetry in patients with predominantly sensory forms of chronic inflammatory demyelinating polyneuropathy (CIDP). Materials and methods. The study involved 57 people with sensory variant of CIDP at the bas of the University Hospital KrasSMU named after Prof. V.F. Voino-Yasenetsky. The age of patients ranged from 12 to 75 years old, the age median was 28 years old. Methods of diagnosis: clinical neurological, neurophysiological. Results. During the transcutaneous oximetry using the equipment «Radiometer TC 4 series» (Copenhagen, Denmark) in patients with chronic inflammatory demyelinating polyneuropathy were predominated, together with normative indices, compensated disorders of tissue metabolism. It was combined with the clinical manifestations of the disease and reflects the degree of angiotrophoneuritic syndrome. Conclusion. Transcutaneous oximetry allows to verify the microcirculation disorders due to involvement nervi vasorum at chronic inflammatory demyelinating polyneuropathy (CIDP).

It was studied the influence of early life stress to the behavior, neurogenesis and apoptosis of brain cells in adult rats of the Wistar. Were established the signs of intensification of processes of brain maturation in newborn, increasing the overall level of anxiety and emotionality, lack of interest to the new stimulus and forming of anxious-depressive behavior in the dynamics of post-natal development in rats undergoing stress in early life. It is shown that the observed behavioral reactions are accompanied by the development of disorders of neurogenesis and apoptosis in the cortex, hippocampus and amygdala of the brain.