南京王安石故居为南京传统民居的代表之一,其装饰纹样丰富多样,整体简约大气,有显著的时代特征.该故居历史悠久,于清末重建,文化内涵丰富,具有重要的研究价值.该文通过对王安石故居中槅扇门窗、屋檐瓦当、螭吻等构件的分析,探究王安石故居建筑的特色、构成、故事背景等,从建造背景、营造技术、思想影响等方面进行文化探源,发掘王安石故居的文化价值内涵,并以王安石故居的修缮方案为例,寻求传统民居的传承、保护与发展策略.

Background: Sepsis is an atypical systemic reaction to infection with high morbidity and mortality. Recently, an association between improved prognosis and obesity in sepsis has been reported; However, the results remain controversial. The objective of the present study was to investigate the association between body mass index (BMI) and sepsis mortality by performing a meta-analysis. Methods: Considering pre-established inclusion and exclusion criteria, eligible studies were retrieved from PubMed, Embase, and Web of Science. Cochran's Q test and I-2 test were used to evaluate the heterogeneity among studies for each outcome. Statistical analysis was conducted using Stata12.0 software (version 12 SE; Stata Corporation, College Station, TX, USA). Odds ratios (OR) and 95% confidence intervals (CI) were used as effect sizes to evaluate differences in hospital, intensive care unit (ICU), 30-day, 90-day, and 1-year mortality in underweight, overweight, and obese patients with sepsis when compared with those with normal-weight.Results: In patients with sepsis, underweight was associated with increased in-hospital, ICU, and 1-year mortality (all odds ratio [OR] > 1, p < 0.05), whereas no significant association was detected with 30- and 90-day mortality (all OR > 1, p > 0.05). The association between underweight and in-hospital mortality disappeared in the non-Asian (OR [95% CI] = 1.13 [0.90, 1.41], p = 0.310) and non-adjusted subgroups (OR [95% CI] = 1.19 [0.92, 1.53], p = 0.186). Overweight was associated with decreased ICU mortality, 30-day mortality, 90-day mortality, and 1-year mortality in patients with sepsis (all OR < 1,p < 0.05), exhibiting no significant association with in-hospital mortality (OR [95% CI] = 0.89 [0.78, 1.01], p = 0.074). Obesity was associated with decreased in-hospital, ICU, 30-day, 90-day, and 1-year mortality in patients with sepsis (all OR < 1,p < 0.05).Conclusions: The results of the present meta-analysis supported the view of the "obesity paradox ". An underweight BMI was associated with increased sepsis mortality, whereas overweight and obesity were associated with low mortality in sepsis. These findings suggest that the clinical management of sepsis should follow the principle of a personalized approach, and the impact of obesity on the pattern of infection, fluids, and antibiotic administration should be carefully considered.

当前,部分现代建筑形式趋于单一,逐渐失去其原有的地域文化特征.针对这一问题,该文从现代主义建筑大师贝聿铭的建筑设计入手,探究现代建筑与地域文化的融合.贝聿铭认为不同地域的现代建筑应有其独特性,在设计前充分调研周边的自然环境、人文环境、地域文化等,并在建筑设计中融入当地的历史文化等要素,以追求现代建筑与当地传统元素的完美结合.该文通过分析苏州博物馆新馆与日本美秀美术馆的案例,探索现代建筑与地域文化的融合.

《布达佩斯大饭店》作为导演韦斯·安德森的巅峰之作,极具欣赏价值,在表达主题、创作背景、拍摄手法、道具服装、视听语言等方面都有独到之处.此外,该电影的色彩运用、艺术表现、画面构成有独特的美学意蕴,极具欣赏与研究价值.本文从社会文化、艺术内涵、多维联系等方面入手,探析该电影的美学意蕴.

紫砂器自肇始至今备受世人珍爱,围绕紫砂器经济价值的讨论,始终是古今艺术品收藏界的热点话题.在明清古籍文献中,关于紫砂器"价埒金玉"的记载频繁出现.文章首先立足于相关史料的梳理,并结合艺术经济学的相关研究方法,考证明清紫砂器"价埒金玉"现象存在的真实性;其次,围绕明清时期紫砂器根植的社会网络、供需关系、社会风尚等因素,分析这种现象产生的深层次原因;最后,剖析紫砂器"价埒金玉"现象对明清时期紫砂工匠及紫砂市场的影响.

Background: This study aimed to examine the effect of convalescent plasma transfusion on patient with severe coronavirus disease ( COVID-19 ) and discussed the main nursing practices. Methods: We retrospectively analyzed the clinical data of 21 patients with severe COVID-19 who had received convalescent plasma transfusion therapy between March 1 and April 1, 2020. The observation indicators included leukocyte, lymphocyte, C-reactive protein (CRP), interleukin-6 (IL-6), and viral antibody levels; test results from pharyngeal swabs; nucleic acid test results; chest CT results; and respiratory symptoms. Further, we summarized the nursing practices related to plasma transfusion. Results: Neither death nor transfusion-related adverse reactions were observed in patients treated with convalescent plasma transfusion. Their antibody levels, especially IgG (P < 0.05), were increased to different levels, whereas the levels of inflammatory markers (CRP), white blood cells, and lymphocytes were significantly decreased (P < 0.05). Respiratory symptoms showed an improvement, and chest CT showed stable findings. Conclusions: Convalescent plasma transfusion is safe and feasible. It can increase antibody levels, reduce inflammatory factor levels, improve white blood cell and lymphocyte counts, and improve respiratory symptoms in patients with severe COVID-19. Thus, plasma transfusion can be used as a new, effective COVID-19 treatment method that requires cooperation from nursing.

价值评估体系是近现代建筑室内历史环境进行保护和更新实践的关键环节,要实现真正合理有效的保护只有在客观、准确的价值评估结果的指导下才行.本文应用因子分析价值评估方法,构建了价值评估指标体系,并将该指标体系应用于北京近现代教堂室内历史环境价值评估中,采用因子分析法客观地对所选评估对象进行价值评估计算,根据价值评估结果将室内历史环境分为四类保护级别,为近现代建筑遗产室内环境保护更新策略和技术的选择提供参考依据.

本文根据儿童患者这个特殊群体的生理和心理特征,遵循安全科学、以人为本的设计原则,全面探讨综合性医院儿科医疗环境的优化设计方案.研究从空间设计、色彩设计、情感体验等方面入手,提出快乐化、差异化、主题化、家庭化的创新设计理念,以期打造更加舒适便捷、具有良好心理体验和疗愈效果的儿科医疗空间,将人性化、生态化和艺术化融入未来的儿科医疗环境优化设计.