Aim. Estimate the efficiency of improved complex therapy of premature with surgical pathology. Materials and methods . 374 medical histories of premature infants were studied. The number of medical histories for 2011 was 169, and the number of medical histories for 2016 was 205. Results. There is an increase in the number of premature with surgical pathology. The number of premature infants increased with a gestation period of less than 28 weeks and decreased among children with a gestation period of 32-34 weeks. The percentage of deceased children with a gestation period of 32-37 weeks has significantly decreased. Decrease in lethality of premature with surgical pathology in 2 times. Conclusion. Results of this study confirmed effectiveness of the improvement of complex therapy of premature with surgical pathology.

One of the most promising activities to improve public health is the assessment, analysis and management of risk factors for disease, disability and mortality. A comparative study of adolescents at social risk and relatively affluent teenagers with the study and analysis of various risk factors for desadaptive behaviors, ranging of the risk factors desadaptive behavior among different groups of teenagers in the Krasnodar region, proposed a comprehensive approach to the correction of disadaptation among modern youth.

Respiratory distress syndrome (RDS) is a major cause of morbidity of newborns of high-risk in early neonatal period and largely determines the rate of infant mortality. The purpose of this research was the assessment of the NG system functioning character and the possibility of immunotherapy of their defects using Likopid based on clinical and immunological analysis of infants with RDS who are on artificial lung ventilation. It was found that infants with RDS on ALV, have significant changes in the functional activity of neutrophilic granulocytes, depending on gestational age and duration of ALV. Functional intubation of NG in the phase of reconvalescence of infants with RDS allowed to reveal a tendency to restoration of the studied parameters, more significant in the group of full-term infants. Preventive use of Likopid for infants with RDS since 2-3 days of life allows to eliminate defects of NG functioning in all clinical groups, and significantly reduce the frequency of pyoinflammatory complications progression (average 30%), improve the quality of care and reduce the risk of chronization process.

This article presents the current views on functional foods of infants. There is described a prebiotic effect of lactulose. There is also presented a microbial landscape of the colon of 20 children artificially fed, and 15 children who are breastfed. With prebiotic purpose to the children of the first group was prescribed lactulose. There is seen an improvement of clinical symptoms and laboratory parameters of children who are bottle-fed. It is recommended as a prebiotic for children deprived of breast milk.

The estimation of efficiency enterosorbtion preparation Polisorb in complex therapy of the tightened jaundices at 34 children born before term on the basis In clinic for newborns In hospital of the first help of Krasnodar is resulted. Age of children from 10 day till 1 month. It is established, that additional introduction in complex therapy preparation Polisorb promoted faster regress of jaundices in comparison with control group.

Active respiratory virus infection remain the most frequent diseases in out-patient practice, constituting 80% of all calls of pediatrists on the house. The estimation of clinical efficiency of a preparation of «umkalor» as a component of pathogenetic therapy has been conducted active respiratory virus infection at frequent and it is long ill children, and also frequency of episodes is evaluated active respiratory virus infection in katamnesis. Inclusion of «umkalor» in complex treatment active respiratory virus infection as a component of pathogenetic therapy allows to increase efficiency of treatment, to lower frequency of occurrence of complications and disease in katamnesis and, as consequence, has economic and social significance.

THE STUDY OF THE ENLARGED THYMUS GLAND SYNDROME IS EXTREMELY IMPORTANT FOR UNDERSTANDING OF THE IMMUNE SYSTEM FORMATION AND FUNCTIONING MECHANISMS. THE PURPOSE OF THIS STUDY IS TO CONDUCT CLINICAL AND IMMUNOLOGICAL ANALYSIS OF THE CHILDREN, SUFFERING FROM THE SYNDROME OF THE ENLARGED THYMUS GLAND HAND III DEGREES, WHO RECEIVED RECOMBINANT ALPHA-2b INTERFERON (IN SUPPOSITORIES). THE REVEALED CHANGES IN THE IMMUNE SYSTEM DURING TIMOMEGALIA ARE COMPLEX AND CONDUCIVE TO THE DEVELOPMENT OF THE INFECTIOUS AND INFLAMMATORY DISEASES AMONG INFANTS, THUS, DETERMINING THE NECESSITY FOR THE ADEQUATE IMMUNE CORRECTION. THE APPLICATION OF THE RECOMBINANT ALPHA-2b INTERFERON AMONG SUCH CHILDREN ALLOWS ONE TO UNCOVER THE IMMUNOMODULATING EFFECTS, NORMALIZING THE IMBALANCES IN THE IMMUNE SYSTEM OF CHILDREN WITH TIMOMEGALIA.