The article presents a clinical case of successful simultaneous surgery for coronary artery disease and newly diagnosed apex lung tumor without postoperative complications.

Comparative analysis of the relationship between the character of dysregeneratory changes occurring in the bronchial epithelium adjacent to the tumor and the development of recurrence of squamous cell and grandular carcinomas of the lung was carried out. The study showed no any relationship between such parameters as tumor size, presence of lymphogenic metastasis, tumor stage and tumor recurrences. The incidence of recurrence in non-small cell lung cancer indirectly related to the character of dysregeneratory changes in the respiratory epithelium of the bronchial mucosa outside the tumor. High incidence rates of squamous cell carcinoma and adenocarcinoma of the lung were observed in cases with combination of basal cell hyperplasia and squamous metaplasia (BCH+SM+).

Immediate response to preoperative chemotherapy with paclitaxel/carboplatin regimen was studied in 134 patients with stage III non-small cell lung cancer using spiral computed tomography (SCT) and fibrobronchoscopy (FBS). SCT and FBS were found to have a high diagnostic efficacy. Sensitivity, specificity and accuracy of SCT were 87,5 %, 96,7 % and 93,4 %. Concerning FBS, sensitivity, specificity and accuracy were 93,3 %, 96,7 %, 95,5 %. The data obtained show that endoscopic examination together with X-ray should be recommended for the assessment of the extent of tumor involvement after chemotherapy.