It was established, that use of Tibet medicine remedy «dig-da-shi-tan» causes faster, than in control group recovery of content levels of DNA, glycogen, levels of ferments activity in hepatocytes, decrease of the fat infiltration in liver, stimulation of cellular and intracellular regeneration of organ the same as inhibition of lipid peroxidation in membrane structures.

The authors carried out morphofunctional estimation of the influence of a medicinal means of plant origin at acute toxic hepatitis in white rats on the basis histological, histochemical, histoenzymological, cytological, cytophotometrical, biochemical and statistical datas. The latter allowed the authors to reveal the basic mechanism of action of a researched means, which was in inhibition of lipids peroxidation of cells membranes and their stabilization.

The stimulating influence of extract of spear-point cacalia Calephlon on reactivation processes in liver of white rats at chronic CCL4-hepatite is stated

It has been found that a complex plant remedy nephrophyt prevents the development of druginduced injury of kidney.

The paper deals with experimental data on combined stimulating effect of polyphenolic compounds from the extract of Gentiana barbata (Froehl) on regenerative processes in acute toxic hepatitis in white rat liver.

The aim of the present work was to perform a morphological assessment of the cerebroprotective action of lanthanum acetate in chronic cerebral ischemia in rats. Chronic ischemia was produced in Wistar rats (weighing 160–180 g) by ligation of both common carotid arteries. Ischemic lesions were corrected by intragastric lanthanum acetate (3 mg/kg per day) throughout the experimental period. Ischemic damage to the cortex was assessed morphometrically on histological sections stained by the Nissl method. Lanthanum acetate was found to suppress the development of ischemic neuron damage in the cerebral cortex, with reductions in the numbers of hyperchromic neurons, cells with focal chromatolysis, and ghost cells, as well as an increase in the number of normochromic cells as compared with controls.

The evaluation of morphofunctional state of white rats kidneys during pharmacological nephropathy activated by kanamycin ingestion has been given in presence of pharmacotherapy with natural medication ‘‘Nephrophyte’’. The nephroprotective action of Nephrophyte ” was displayed.

Our studies show that a combined herbal medicine neurofit has a pronounced neuroprotective effect in experimental alcoholic intoxication. The principal mechanism of this neuroprotective effect lies in neurofit ability to inhibit lipid peroxidation and stimulate the antioxidant system.

LA influences on the coagulatious system of blood, stage of hypercoagulation in experimental model of disseminated intravascular coagulation syndrome. It increases the activity of thromboplastin and thrombins formation, reduces the degree of hypercoagulation and accelerates fibrinolytic activity. LA prevents the development of disseminated intravascular coagulation syndrome reducing the level of thrombocytopenia and deficiency of plasmatic factors; the interaction of coagulative and fibrinolytic systems is restored.

The objective of this study was to evaluate morphologically the cerebroprotective effect of lanthanum acetate in chronic cerebral ischemia. Chronic cerebral ischemia was reproduced in Wistar rats, weighing 160-180 g, by a ligation of both common carotid arteries. For corection of ischemic cerebral damage, lanthanum acetate (3 mg/kg of body weight, once a day) was introduced intragastrically during the whole experimental period. Ischemic damage of the cerebral cortex was evaluated morphologically in Nissl stained histological sections. Lanthanum acetate was found to suppress the development of ischemia-induced neuronal damage in cerebral hemispheres: the numbers of hyperchromatic neurons, cells with focal chromatolysis, and ghost cells were reduced, while the number of normochromatic neurons was increased in experimental group as compared to those in controls.

LA assists the normalization of thrombocytical haemostasis suppressing the range of trombocytes aggregation and the activity of blood coagulation factors and therefore infl uencing on microcirculation positively. LA interferes with increasing of blood coagulation, suppresses thrombocytes aggregation and the activity of plasmatic factors of blood coagulation.

The research nephroprotective effect of the phytoextract«Nephrophyt» has been carried out in toxic lesion of kidneys, connected with the combined introduction of antituberculous preparations: izoniazide, rephampicine, and pirazinamide. It has established, that «Nephrophyt» considerably reduces nephrotoxicity of tuberculostatics, provide thes expressed antioxidative effect.