Piyush K. Dhnauka, M.

Journal of Veterinary Internal MedicineVolume 7, Issue 3 p. 199-201 Open Access Clinical Vignette Carolyn J. Henry DVM, Carolyn J. Henry DVM College of Veterinary Medicine Auburn UniversitySearch for more papers by this authorWilliam G. Brewer Jr. DVM, William G. Brewer Jr. DVM College of Veterinary Medicine Auburn UniversitySearch for more papers by this authorR. D. Montgomery DVM, MS, R. D. Montgomery DVM, MS College of Veterinary Medicine Auburn UniversitySearch for more papers by this authorA. H. Groth Jr. DVM, MS, A. H. Groth Jr. DVM, MS College of Veterinary Medicine Auburn UniversitySearch for more papers by this authorR. E. Cartee DVM, MS, R. E. Cartee DVM, MS College of Veterinary Medicine Auburn UniversitySearch for more papers by this authorK. Scott Griffin DVM, K. Scott Griffin DVM Carriage Hills Veterinary Clinic Montgomery, ALSearch for more papers by this author Carolyn J. Henry DVM, Carolyn J. Henry DVM College of Veterinary Medicine Auburn UniversitySearch for more papers by this authorWilliam G. Brewer Jr. DVM, William G. Brewer Jr. DVM College of Veterinary Medicine Auburn UniversitySearch for more papers by this authorR. D. Montgomery DVM, MS, R. D. Montgomery DVM, MS College of Veterinary Medicine Auburn UniversitySearch for more papers by this authorA. H. Groth Jr. DVM, MS, A. H. Groth Jr. DVM, MS College of Veterinary Medicine Auburn UniversitySearch for more papers by this authorR. E. Cartee DVM, MS, R. E. Cartee DVM, MS College of Veterinary Medicine Auburn UniversitySearch for more papers by this authorK. Scott Griffin DVM, K. Scott Griffin DVM Carriage Hills Veterinary Clinic Montgomery, ALSearch for more papers by this author First published: May 1993 https://doi.org/10.1111/j.1939-1676.1993.tb03188.xCitations: 33AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1 Rijnberk A., van Wees A., Mol JA. Assessment of two tests for the diagnosis of canine hyperadrenocorticism. Vet Rec 1988; 122: 178– 180. 2 Beckman DL, Iams SG. Circulating catecholamines in cats before and after lethal head injury. Proc Soc Exp Biol Med 1979; 160: 200– 202. 3 Newell K.A, Prinz RA, Brooks MH, et al. Plasma catecholamine changes during excision of pheochromocytoma. Surgery 1988; 104: 1064– 1073. 4 Wheeler SL. Endocrine tumors. In: SJ Withrow, EG MacEwan, eds. Clinical Veterinary Oncology. Philadelphia : JB Lippincott Company 1989; 253– 282. 5 Landsberg L., Young JB. Catecholamines and the adrenal medulla. In: JD Wilson, DW Foster, eds. Williams Textbook of Endocrinology, 8th Ed. Philadelphia : WB Saunders Company, 1992; 621– 705. 6 Twedt DC, Tilley LP, Ryan WW, et al. Grand rounds conference: pheochromocytoma in the canine. J Am Anim Hosp Assoc 1975; 11: 491– 496. 7 Bouayad H., Feeney A., Caywood DD, et al. Pheochromocytoma in dogs: 13 cases (1980–1985). J Am Vet Med Assoc 1987; 191: 1610– 1615. 8 Beard CM, Sheps SG, Kurkland LT, et al. Occurrence of pheochromocytoma in Rochester, Minnesota: 1950 through 1979. Mayo Clin Proc 1983; 58: 802– 804. 9 Schaer M.. Pheochromocytoma in a dog: a case report. J Am Anim Hosp Assoc 1980; 16: 583– 587. 10 Patnaik AK, Erlandson RA, Lieberman PH, et al. Extra-adrenal pheochromocytoma (paraganglioma) in a cat. J Am Vet Med Assoc 1990; 197: 104– 106. 11 Perry RR, Keiser HR, Norton JA, et al. Surgical management of pheochromocytoma with the use of metyrosine. Ann Surg 1990; 212: 621– 628. 12 Scott HW, Reynolds V., Green N., et al. Clinical experience with malignant pheochromocytoma. Surg Gynecol Obstet 1982; 154: 801– 818. Citing Literature Volume7, Issue3May 1993Pages 199-201 ReferencesRelatedInformation

A 3-year-old bull was examined because of a fluctuant mass on the ventral midline of the cranial portion of the cervical area. The mass originally developed after the bull was handled in a squeeze chute for routine health care. The mass was aspirated and incised repeatedly during the 18 months before referral. The mass was excised at the referral center, and the histologic diagnosis was dermoid cyst. The mass had not redeveloped by 18 months after surgery. Dermoid cysts are most often seen in Rhodesian Ridgeback dogs, although a similar condition has been reported in a 5-week-old calf.

Metastatic thymic lymphosarcoma was diagnosed in a 16-month-old mixed-breed heifer with a history of progressive weight loss. Physical examination revealed cachexia, pale mucous membranes, large peripheral lymph nodes, and a 15 X 40-cm mass in the ventral portion of the neck, extending cranially from the thoracic inlet. Neoplastic lymphocytes were identified in aspirates of pleural effusion and bone marrow. Histologic examination of necropsy specimens substantiated metastatic dispersal of the tumor into lymphoid tissue, liver, intestine, heart, and kidney. This case differs from other reported cases of thymic lymphosarcoma because of the involvement of organs other than the thymus and lymph nodes. Analytical flow cytometry was performed on mononuclear leukocytes obtained from blood by use of density gradient centrifugation. The majority of cells (65%) appeared to be of an immature, poorly differentiated phenotype, on the basis of the small numbers of cells stained with monoclonal antibodies specific for the following cell surface markers: 8% BoCD2 (IL-A26; sheep erythrocyte receptor on T-lymphocytes); less than 10% B-lymphocytes as determined by expression of MHC class II proteins and surface immunoglobulin; 12% monocytes (IL-A24); and 5% null cells (IL-A29). Although the leukemic cell population did not express traditional surface markers for T-lymphocytes, we hypothesize that the leukemic cell population represents an early stage of T-cell maturation that has failed to differentiate and express characteristic cell surface antigens.