Ovarian carcinosarcoma is a rare malignant gynecological tumor that accounts for about 1% of all ovarian cancers. The positive diagnosis of this disease is based on clinical examination, radiological examinations and essentially histological confirmation: the association of a carcinomatous component with a sarcomatous component. Generally, the treatment performed is surgical cytoreduction, followed by chemotherapy and/or radiotherapy. As the prognosis is poor, the survival rate will depend mainly on the quality of surgical management.Multicenter or multinational studies, based on genetic and molecular signaling pathways, are required to better understand this tumor subtype and compare its treatment modalities.
Goal: Evaluate the techniques and results obtained from the mammary Oncoplastic in the conservative treatment of breast cancer. Patients and methods: This is a retrolective descriptive study conducted during the period from 3 April 2017 to 3 April 2019, the Gynecologic Breast pole of the Oncology National Institute of Rabat. Results: Out of 105 files listed, the locations of the tumours were: 35% 37/105 QSE, QSI QSE + 21/105 or 20%, QSI 19/105 or 18%, QSI 12/105 or 11%, other maps 16/105 or 16%. The techniques were Oncoplastic: Pamectomy 10/105 or 10% Round Block 58/105 or 55%, plasty inverted T 21/105 or 20%, and other technical 16/105 or 15%. The aesthetic results and the quality of resection were correct and above all stable at 82/105 patients 78% of cases. The lymphocele 13/105 or 12% 5/105 5% lymphoedema represented early complications occurred as late complications consisted of retractile unsightly scars 15/105 or 14%, breast asymmetry 13/105 soit12% and cutaneous sclerosis 3/105 or 3%. Conclusion: The oncoplastic surgery is a part of multidisciplinary management of breast cancer. It imposes oncologic resections and reassuring cosmetic results for the patient and the practitioner.
Uterine sarcomas are malignant tumors with poor prognosis. The purpose is to clarify the epidemiological, diagnostic difficulties and therapeutic modalities and prognosis of uterine sarcomas. Twelve cases of uterine sarcomas supported the National Institute of Oncology (2008-2011) were analyzed. The average age is 43.75 years. Patients viewed had the clinical triad of bleeding, pain and / or pelvic mass. On the para-clinical, seven patients had an inconclusive ultrasound, however the scan was performed in all our patients showing a pelvic mass. The realization of the biopsy endometrial curettage led to the diagnosis. All patients underwent a hysterectomy associated with lymph node dissection in cases with carcinomatous component. Histological analysis of surgical specimens objectified 06 carcinosarcomas, 03 leiomyosarcoma, 02 endometrial stromal sarcoma and an adenosarcoma. In our study in discordance with the literature, the mixed mesenchymal tumors (carcinosarcoma and adenosarcoma) are the most common histological type 58.33% followed by pur sarcoma (sarcoma and endometrial stromal leiomyosarcoma) with a frequency of 41.67%. The average age of patients (43.75 years) is consistent with the literature. The classic clinical triad, reported by most authors, was found in the majority of patients. MRI and PET scan are the most successful exams. The diagnosis rests on hysterectomy’s piece. For treatment, surgery with hysterectomy and adnexectomy with or without lymph node dissection followed by external radiation therapy is the gold standard. Indeed, uterine sarcomas are malignant tumors with poor prognosis whose diagnosis is primarily postoperative. Surgery with radiation therapy is the gold standard. Hope rests on new drugs that are being tested.
Le rhabdomyosarcome est une tumeur mésenchymateuse rare. La localisation paratesticulaire est la plus fréquente des localisations urogénitales. C’est une tumeur qui intéresse surtout l’enfant et reste exceptionnelle chez l’adulte. Le pronostic est mauvais, et le traitement repose sur le trépied chirurgie, chimiothérapie et radiothérapie. À la lumière d’une revue de la littérature, nous discutons les modalités diagnostiques et thérapeutiques de cette tumeur.
Le cancer colique occupe le premier rang des cancers digestifs. Les signes d’appel sont dominés par les troubles du transit, les rectorragies et les douleurs. Cependant un cancer colique peut être découvert suite à une complication à savoir un syndrome occlusif, une perforation. Bien qu’elles soient fréquentes au moment du diagnostic (25 % des patients), les métastases synchrones constituent un mode révélateur exceptionnel de ce cancer.
Colon cancer ranks first among digestive cancers. The warning signs are dominated by transit disorders, rectal bleeding and pain. However, a colon cancer can be discovered following a complication namely a bowel obstruction, a perforation. Although they are common at diagnosis (25% of the patients), synchronous metastases are an exceptional way of revealing this cancer.We report a case of synchronous ovarian metastasis isolated jacks for an ovarian tumor and revealing a colonic tumor remained asymptomatic until then.
The clear cell adenocarcinoma of the cervix at the girl is very rare. Certainly, a number of factors are known predisposing in particular the role of the HPV and the treatment with Di-Ethyl-Stilboestrol taken during the pregnancy by the mother. However, its etiopathology remains largely mysterious, what is the case of the clinical observation that we report in which we insist on the dark prognosis of this cancer.
Les auteurs rapportent l’observation des métastases jéjunales d’un mélanome cutané révélées par une invagination intestinale aiguë. Cette complication reste exceptionnelle.
Le condylome acuminé géant (CAG) ou tumeur de Buschke-Lowenstein est une tumeur qui affecte principalement les secteurs génitaux et périanaux. Malgré l’aspect histologique bénin, il se comporte comme une tumeur maligne en détruisant les tissus adjacents. Le human papillomavirus (HPV) est l’agent causal. Le risque du CAG est le taux élevé de récidive locale et la dégénérescence maligne en carcinome épidermoïde. Nous décrivons un cas de CAG dégénéré.
Paget’s disease of the nipple is a rare form of breast malignancy. Underlying breast cancer, either in situ or invasive accompanies lesions of the nipple in most of the cases. The connection between both entities and their exact origin remains unclear. Nevertheless, underlying ductal breast cancer is often confined to the central, subareolar part of the breast. Radical mastectomy, although successful, seems to be too mutilating treatment in the era of breast sparing surgery. Studies describing breast conserving surgery performed without adjuvant treatment are rare and the patients not numerous. Due to low incidence of the disease, there are no randomised trials conducted which could show the optimal method of treatment.We performed cryosurgery of the affected nipple-areola complex (NAC) in treatment of six patients with Paget’s disease of the nipple who presented general contraindications or lack of consent for surgery.With a follow up ranging from 60 to 121 months (average 94) we obtained very good results in terms of disease specific survival: there were two cases of recurrent disease, confined to the scar and treated successfully with cryosurgery again; four patients are alive without disease. Death was not related to cancer in the remained two cases.Cryotherapy is successful form of treatment of localised Paget’s disease of the nipple – especially in face of contraindications for surgery or lack of patient’s agreement for operational treatment.
Giant condyloma acuminatum (GCA) or Buschke- Lowenstein tumor is a tumor that primarily affects the genital and perianal areas. Despite the histologically benign appearance, it behaves in a malignant fashion, destroying adjacent tissues. The human papilloma virus is the causative agent. The hallmark of GCA is the high rate of local recur- rence and transformation into squamous cell carcinoma. We describe a case of GCA complicated by malignant transfor- mation. To cite this journal: J. Afr. Cancer 3 (2011).