目的 观察系统康复护理对卒中后气管切开患者的护理效果.方法 对近期住院的60例气管切开患者进行回顾性分析,根据护理方式不同,分为常规护理组和系统康复组,对比其护理效果.结果 系统康复组患者的护理效果明显优于常规护理组,P<0.05.结论 在卒中后气管切开患者的护理中,系统康复护理的疗效确切,能够改善其病症,并减少患者的并发症风险.

Objective:To explore the effect of Regulating channels and activating collateral lotions on the quality of life and fatigue symptoms of patients with post-stroke fatigue(PSF).Methods:A retrospective analysis of 100 patients with post-stroke fatigue who were admitted to the Rehabilitation Department of Guangdong Provincial Hospital of Chinese Medicine from October 2014 to October 2016 and met the inclusion criteria of this study were divided into the treatment group and control group(50 cases in each group)according to the random number table method. The control group was treated with routine nursing care and comprehensive rehabilitation training, while the treatment group was additionally treated with Regulating channels and activating collateral lotions, and each group was observed for two weeks. Before and after treatment, the fatigue severity scale(FSS), the multidimensional fatigue inventory-20(MFI-20)and the energy score of the stroke-specific quality of life(SS-QOL-E)were used to assess the degree of fatigue and the improvement in quality of life.Results:After the treatment, the FSS score and MFI-20 score of the two groups were significantly lower, while SS-QOL-E score was significantly higher than that of before the treatment(P<0.05).After the treatment, the FSS score and MFI-20 score of the treatment group were significantly lower, and the SS-QOL-E score was significantly higher than that of the control group(P<0.05).Conclusion:On the basis of comprehensive rehabilitation training combined with routine nursing, supplemented with Regulating channels and activating collateral lotions can effectively alleviate the symptoms of fatigue after stroke and improve the quality of life, and the curative effect is better than that of comprehensive rehabilitation training combined with routine nursing.

Objective:To observe the effects of ambient particulate matter (PM2.5) on the proliferation and secretion levels of cytokines of children’s bone marrow stromal cells (BMSCs) and to explore the effects of PM2.5 on children’s bone marrow hematopoietic microenvironment.Method:The collected BMSCs were exposed to different concentration of PM2.5 solutions.The proliferation of BMSCs and the secretion levels of G-CSF, GM-CSF and mRNA were detected.Result:The BMSCs proliferation increased with the increase of concentration of PM2.5 solution,after 50μg/mL the proliferation of BMSCs level gradually decline.The proliferation of BMSCs level with concentration 20μg/mL of experimental group was significantly higher than control,while 100μg/mL of experimental group was significantly lower than control group,the differences were statistically significant (P<0.05).The low concentration of PM2.5 with 10 and 20μg/mL promoted the secretion levels of G-CSF, GM-CSF and mRNA,while gradually inhibited in the PM2.5 concentration of 50,100 and 200μg/mL.The concentration reaches more than 100μg/mL,inhibiting effects reached significant level.Conclusion:The high concentration of PM2.5 has a certain toxic effect on children’s BMSCs.

目的：了解慢性免疫性血小板减少性紫癜患儿的生活质量现状。方法应用儿少主观生活质量问卷（ ISLQ）对慢性免疫性血小板减少性紫癜患儿（病例组）的生活质量进行调查，并选取同地区的健康儿童（对照组）作为对照。结果病例组在认知满意度、情感满意度和生活质量总体满意度上得分均较对照组明显降低（P＜0．05）。除焦虑体验维度的得分与对照组差异无统计学意义外，其余各维度的得分均明显较对照组降低，差异有统计学意义（ P＜0．05）。结论慢性免疫性血小板减少性紫癜患儿的生活质量明显降低，应从家庭、医疗、学校等各方面采取具有针对性的改善措施。

目的 探讨湘西南少数民族地区居民生存质量现状,分析其影响因素.方法 随机抽取湖南省新宁县少数民族地区482名居民,采用世界卫生组织生存质量测定量表(WHOQOL-BREF)进行问卷调查.结果 全部482名居民生存质量得分生理领域(58.42±14.73)分,心理领域(57.37±13.39)分,社会关系领域(60.20±15.05)分,环境领域(52.40±13.92)分;生理、心理、社会关系、环境领域生存质量高文化程度居民高于低文化程度居民(F=23.235、24.222、19.602、16.838,P＜0.05),非农业劳动者高于农业劳动者(t=-3.838、-3.723、-3.139、-3.154,P＜0.05),高收入居民高于低收入居民(F=15.400、15.953、5.988、18.042,P＜0.05),未婚居民高于已婚居民、离婚和丧偶居民(F=15.400、15.953、5.988、18.042,P＜0.05),年龄越大,生存质量得分越低(F=31.191、14.614、12.146、11.211,P＜0.05);社会关系领域生存质量其他少数民族居民高于瑶族居民和汉族居民(F=4.514,P＜0.05);不同性别居民生存质量得分差异无统计学意义(P＞0.05).Logistic回归分析显示年龄、民族、文化程度是少数民族地区居民生存质量自我综合评分的影响因素(P＜0.05).结论 湘西南少数民族地区居民生存质量的影响因素主要有文化程度、民族、收入水平等.应从教育、民族交流、经济发展等方面提高少数民族居民的生存质量.