We report the development of an instrumentation and control system instantiated on a microprocessor-field programmable gate array (FPGA) device for a harmonic oscillator comprising a portion of a magnetic resonance force microscope. The specific advantages of the system are that it minimizes computation, increases maintainability, and reduces the technical barrier required to enter the experimental field of magnetic resonance force microscopy. Heterodyne digital control and measurement yields computational advantages. A single microprocessor-FPGA device improves system maintainability by using a single programming language. The system presented requires significantly less technical expertise to instantiate than the instrumentation of previous systems, yet integrity of performance is retained and demonstrated with experimental data.

From a non-equilibrium thermodynamical framework for transport analysis based on Onsager's Regression Hypothesis, we derive the value function first described by Dirac for isotope separation. This application of the framework is interpreted as both further validation of the transport framework and as a generalization of Dirac's value function. The framework for the analysis of transport phenomena is introduced, first. From the entropy of mixing, and in the presence of gradients in thermodynamic potentials, this framework generates a dynamical transport model from which Dirac's value function is derived as a measure of separative work performed. Dirac's value function is thus shown to be a measure of separative work for systems that are described by the entropy of mixing. As a further demonstration of its generality, the result is applied to a two-quantity, single spatial-dimension spin magnetization system.

We present a framework for modeling the transport of any number of globally conserved quantities in any spatial configuration and apply it to obtain a model of magnetization transport for spin-systems that is valid in new regimes (including high-polarization). The framework allows an entropy function to define a model that explicitly respects the laws of thermodynamics. Three facets of the model are explored. First, it is expressed as nonlinear partial differential equations that are valid for the new regime of high dipole-energy and polarization. Second, the nonlinear model is explored in the limit of low dipole-energy (semi-linear), from which is derived a physical parameter characterizing separative magnetization transport (SMT). It is shown that the necessary and sufficient condition for SMT to occur is that the parameter is spatially inhomogeneous. Third, the high spin-temperature (linear) limit is shown to be equivalent to the model of nuclear spin transport of Genack and Redfield. Differences among the three forms of the model are illustrated by numerical solution with parameters corresponding to a magnetic resonance force microscopy (MRFM) experiment. A family of analytic, steady-state solutions to the nonlinear equation is derived and shown to be the spin-temperature analog of the Langevin paramagnetic equation and Curie's law. Finally, we analyze the separative quality of magnetization transport, and a steady-state solution for the magnetization is shown to be compatible with Fenske's separative mass transport equation.

We present a framework for modeling the transport of any number of globally conserved quantities in any spatial configuration and apply it to obtain a model of magnetization transport for spin-systems that is valid in new regimes (including high-polarization). The framework allows an entropy function to define a model that explicitly respects the laws of thermodynamics. Three facets of the model are explored. First, it is expressed as nonlinear partial differential equations that are valid for the new regime of high dipole-energy and polarization. Second, the nonlinear model is explored in the limit of low dipole-energy (semi-linear), from which is derived a physical parameter characterizing separative magnetization transport (SMT). It is shown that the necessary and sufficient condition for SMT to occur is that the parameter is spatially inhomogeneous. Third, the high spin-temperature (linear) limit is shown to be equivalent to the model of nuclear spin transport of Genack and Redfield. Differences among the three forms of the model are illustrated by numerical solution with parameters corresponding to a magnetic resonance force microscopy (MRFM) experiment. A family of analytic, steady-state solutions to the nonlinear equation is derived and shown to be the spin-temperature analog of the Langevin paramagnetic equation and Curie's law. Finally, we analyze the separative quality of magnetization transport, and a steady-state solution for the magnetization is shown to be compatible with Fenske's separative mass transport equation.

The practical focus of this work is the dynamical simulation of polarization transport processes in quantum spin microscopy and spectroscopy. The simulation framework is built-up progressively, beginning with state-spaces (configuration manifolds) that are geometrically natural, introducing coordinates that are algebraically natural; and finally specifying dynamical potentials that are physically natural; in each respect explicit criteria are given for naturality. The resulting framework encompasses Hamiltonian flow (both classical and quantum), quantum Lindbladian processes, and classical thermostatic processes. Constructive validation and verification criteria are given for metric and symplectic flows on classical, quantum, and hybrid state-spaces, with particular emphasis to tensor network state-spaces. Both classical and quantum examples are presented, including dynamic nuclear polarization (DNP). A broad span of applications and challenges is discussed, ranging from the design and simulation of quantum spin microscopes to the design and simulation of quantum oracles.

We report on an all-sky search with the LIGO detectors for periodic gravitational waves in the frequency range 50-1000 Hz and with the frequency's time derivative in the range -1.0E-8 Hz/s to zero. Data from the fourth LIGO science run (S4) have been used in this search. Three different semi-coherent methods of transforming and summing strain power from Short Fourier Transforms (SFTs) of the calibrated data have been used. The first, known as "StackSlide", averages normalized power from each SFT. A "weighted Hough" scheme is also developed and used, and which also allows for a multi-interferometer search. The third method, known as "PowerFlux", is a variant of the StackSlide method in which the power is weighted before summing. In both the weighted Hough and PowerFlux methods, the weights are chosen according to the noise and detector antenna-pattern to maximize the signal-to-noise ratio. The respective advantages and disadvantages of these methods are discussed. Observing no evidence of periodic gravitational radiation, we report upper limits; we interpret these as limits on this radiation from isolated rotating neutron stars. The best population-based upper limit with 95% confidence on the gravitational-wave strain amplitude, found for simulated sources distributed isotropically across the sky and with isotropically distributed spin-axes, is 4.28E-24 (near 140 Hz). Strict upper limits are also obtained for small patches on the sky for best-case and worst-case inclinations of the spin axes.

Achieving 3-dimensional, in-depth, atomic-resolution biological microscopy of undenatured specimens is one of the oldest dreams of science, and for good reason: it unites the thrilling prospect of opening vast new scientific frontiers with cutting-edge technical challenges from every domain of mathematics, science, and engineering.

This article presents numerical recipes for simulating high-temperature and non-equilibrium quantum spin systems that are continuously measured and controlled. The notion of a spin system is broadly conceived, in order to encompass macroscopic test masses as the limiting case of large-j spins. The simulation technique has three stages: first the deliberate introduction of noise into the simulation, then the conversion of that noise into an equivalent continuous measurement and control process, and finally, projection of the trajectory onto a state-space manifold having reduced dimensionality and possessing a Kahler potential of multi-linear form. The resulting simulation formalism is used to construct a positive P-representation for the thermal density matrix. Single-spin detection by magnetic resonance force microscopy (MRFM) is simulated, and the data statistics are shown to be those of a random telegraph signal with additive white noise. Larger-scale spin-dust models are simulated, having no spatial symmetry and no spatial ordering; the high-fidelity projection of numerically computed quantum trajectories onto low-dimensionality Kahler state-space manifolds is demonstrated. The reconstruction of quantum trajectories from sparse random projections is demonstrated, the onset of Donoho-Stodden breakdown at the Candes-Tao sparsity limit is observed, a deterministic construction for sampling matrices is given, and methods for quantum state optimization by Dantzig selection are given.

It is critical that surgeons comprehend the normal laxity of the glenohumeral joint (1) to assist them in diagnosing conditions of clinical instability and (2) to help define a therapeutic end point for the management of shoulders with excessive stiffness. In clinical practice this joint laxity is judged by standard manual tests. We report a quantitative study of the clinical in vivo laxity of the normal shoulders of eight male volunteers. To our knowledge this is the first time that the laxity revealed on standard manual clinical tests has been quantified in vivo. The relative motions of the humerus and scapula were determined with an electromagnetic spatial tracker. This device was pinned percutaneously to the humerus and scapula of each of eight normal male volunteers of ages 25 to 45 years. An experienced shoulder surgeon carried out standard manual clinical tests of glenohumeral laxity while the resulting displacements of the humeral head relative to the glenoid were measured. Spatial tracker data indicated that for each of the different tests, the positions of the glenohumeral and scapulothoracic joints were reproducible for a given subject and among subjects. Substantial glenohumeral translations were measured during those manual laxity tests in which the joint was not at the limit of its range of motion: the drawer test, 7.8 ± 4.0 mm anterior and 7.9 ± 5.6 mm posterior; the sulcus test, 10.6 ± 3.8 mm inferior; and the push-pull test, 9.0 ± 6.3 mm posterior. A minimal translation of 0.3 ± 2.5 mm was measured during the fulcrum test in which the glenohumeral ligaments were under tension. The observed translations were reproducible in each subject's shoulder. On the other hand, there was marked variability among subjects. Even though manual laxity tests are a standard part of the clinical evaluation of the shoulder, our finding that normal glenohumeral joints show substantial translations indicates that translation on clinical manual laxity testing is not in and of itself a sufficient indication for surgical stabilization.

Received 29 February 2008DOI:https://doi.org/10.1103/PhysRevD.77.069903©2008 American Physical Society

We report on a search for gravitational waves from the coalescence of compact binaries during the third and fourth LIGO science runs. The search focused on gravitational waves generated during the inspiral phase of the binary evolution. In our analysis, we considered three categories of compact binary systems, ordered by mass: (i) primordial black hole binaries with masses in the range 0.35 M(sun) < m1, m2 < 1.0 M(sun), (ii) binary neutron stars with masses in the range 1.0 M(sun) < m1, m2 < 3.0 M(sun), and (iii) binary black holes with masses in the range 3.0 M(sun)< m1, m2 < m_(max) with the additional constraint m1+ m2 < m_(max), where m_(max) was set to 40.0 M(sun) and 80.0 M(sun) in the third and fourth science runs, respectively. Although the detectors could probe to distances as far as tens of Mpc, no gravitational-wave signals were identified in the 1364 hours of data we analyzed. Assuming a binary population with a Gaussian distribution around 0.75-0.75 M(sun), 1.4-1.4 M(sun), and 5.0-5.0 M(sun), we derived 90%-confidence upper limit rates of 4.9 yr^(-1) L10^(-1) for primordial black hole binaries, 1.2 yr^(-1) L10^(-1) for binary neutron stars, and 0.5 yr^(-1) L10^(-1) for stellar mass binary black holes, where L10 is 10^(10) times the blue light luminosity of the Sun.

Received 29 February 2008DOI:https://doi.org/10.1103/PhysRevD.77.069905©2008 American Physical Society

Received 29 February 2008DOI:https://doi.org/10.1103/PhysRevD.77.069902©2008 American Physical Society

Received 29 February 2008DOI:https://doi.org/10.1103/PhysRevD.77.069904©2008 American Physical Society