Adolescents are prone to nonsuicidal self-injury, a unique risk factor for suicide and suicide attempts. Prior research has shown that cyberbullying predicts adolescent nonsuicidal self-injury behavior. Therefore, this study aimed to develop a chain mediation model to investigate the impact of shame and dissociation related to cyberbullying on teenage nonsuicidal self-injury. Between 23/04/2022 and 26/04/2022, researchers recruited 14,666 high school students in Zizhong County, Sichuan Province, China, to investigate cyberbullying, non-suicidal self-injurious behaviors, shame, and feelings of dissociation through self-report questionnaires. Among the participating high school students, 56.0% reported experiencing cyberbullying and 25.4% reported nonsuicidal self-injurious behaviors. After adjusting for the effects of gender, traditional bullying, grade level, left-behind child status, and parental marital status, there was a positive correlation between cyberbullying and adolescent nonsuicidal self-injurious behavior. Shame and dissociation played a mediating role between cyberbullying and adolescent nonsuicidal self-injury. First, a partial mediating effect of shame and dissociation was observed, with the mediating effect accounting for 6.1% and 21.2% of the total effect (33.0%), respectively; thereafter, a chain mediating effect of shame and dissociation was noted, with the mediating effect accounting for 9.1% of the total effect. In the parallel mediation test, the mediating effect of dissociative experience (0.10) was higher than that of shame (0.02). Cyberbullying and non-suicidal self-injury are prevalent among high school students in western China, and the synergistic effects of shame and dissociation may be associated with increased risk of adolescent non-suicidal self-injury.

Suicidal behavior is a major public mental health concern during adolescence and is closely linked to borderline personality features and internalizing symptoms. Symptom network analysis may help clarify the complex interrelations among borderline personality features, depressive and anxiety symptoms, and suicide-related behaviors by identifying central and bridge nodes. This cross-sectional survey was conducted between September and October 2023 in three secondary schools in Nanning, Guangxi, China. Students aged 12–18 years completed the Borderline Personality Features Scale for Children, Patient Health Questionnaire-9, Generalized Anxiety Disorder-7, and Suicidal Behaviors Questionnaire-Revised. A sparse Gaussian graphical model was estimated using Spearman correlations with EBICglasso; centrality and bridge centrality were computed. Network accuracy was evaluated via bootstrapping, and sex-stratified network differences were tested using NetworkComparisonTest. A total of 5,572 adolescents were included (age 12–18, 53.9

Adolescence is a period marked by emotional volatility, interpersonal vulnerability, and underdeveloped cognitive control, making youths especially susceptible to non-suicidal self-injury. Distinct forms of NSSI may differ in psychological function and clinical relevance. This study is the first to employ network analysis with dual network models to examine the complex interplay among emotion regulation, interpersonal sensitivity, cognitive insight, and 18 specific NSSI behaviors in adolescents. The primary goal was to identify key psychological nodes and central NSSI behaviors within the network structure to inform more targeted prevention and intervention strategies. A total of 5572 adolescents (ages 12–18; 53.9

BACKGROUND AND AIMS:Nowadays, smartphone addiction (SA) has become a widespread issue; however, research specifically targeting high school adolescents remains limited. To address this gap, this study aimed to identify important predictive factors of SA among high school students using machine learning and to explore the relationships among these factors through network analysis, thereby providing a theoretical foundation for targeted interventions. METHODS:A total of 14,036 high school students aged 15-18 years (M = 16.40) were included for model training and internal validation. The Extreme Gradient Boosting (XGBoost) algorithm was applied to evaluate the importance of 20 candidate variables, ranked using SHAP values, from which the top nine predictors were selected. Network analysis was then employed to examine the connections among these predictors. RESULTS:The XGBoost model achieved the highest predictive performance among tested approaches. Network analysis revealed that anxiety was the most central factor, showing positive associations with interpersonal sensitivity and mood swings. CONCLUSIONS:XGBoost combined with network analysis is an effective approach for identifying and exploring SA-related factors among high school adolescents. The identified predictors provide valuable insights for designing targeted and evidence-based interventions for SA in this population.

Background In China,the structure shift from just one-child family to both one-child and more-than-one-child families is happening.Exploring how the sibling relationships effect between adolescent personality impulsivity and aggressivity is of great significance for promoting adolescent mental health as well as maintaining social harmony and stability.Objective To investigate the effecting path of sibling relationships between personality impulsivity and aggressivity in adolescents,so as to provide references for the prevention of violent and aggressive behavior in adolescents.Methods From February to April,2023,a total of 1 200 students with sibling relationships from 12 primary and secondary schools in a county of Sichuan province were included by random sampling.Barratt Impulsivity Scale(BIS-11),Chinese Version of Buss&Perry Aggression Questionnaire(AQ-CV),and Sibling Relationship Questionnaire(SRQ)were used for cross-sectional investigation.Pearson Correlation Analysis was used to analyze the correlation between the scores of these scales.Bootstrap method was used to test the effecting path of sibling relationships between personality impulsivity and aggressivity.Results The total score of BIS-11 was positively correlated with that of AQ-CV as well as the scores of conflict and competition dimensions in SRQ(r=0.485、0.276、0.280,P<0.01),while negatively correlated with the score of warmth/intimacy dimension in SRQ(r=-0.383,P<0.01).The total score of AQ-CV was positively correlated with the scores of conflict and competition dimensions in SRQ(r=0.387,0.340,P<0.01),while negatively correlated with the score of warmth/intimacy dimension in SRQ(r=-0.304,P<0.01).Within SRQ,negative correlations could be observed between the score of warmth/intimacy and scores of conflict and competition(r=-0.307,-0.375,P<0.01),whereas positive correlation could be observed between the score of conflict and that of competition(r=0.267,P<0.01).The total effect of personality impulsivity level on aggressivity level in adolescent was 0.480(P<0.01).Sibling relationships played a mediating role between personality impulsivity and aggressivity in adolescents.Meanwhile,the indirect effect values of warmth/intimacy,conflict and competition were 0.054,0.075 and 0.062,with the effect values accounting for 11.21％,15.70％and 12.93％,respectively.Conclusion The personality impulsivity of adolescents can directly affect their aggressivity,and sibling relationships may act as an important channel connecting personality impulsivity and aggressivity.

Background Peer victimization (PV) is one of the major causes of non-suicidal self-injury. Non-suicidal self-injury (NSSI), peer victimization, social anxiety, and mobile phone addiction are significantly related; however, the interaction mechanism and effect of sex differences remain to be determined. Objective Herein, we investigated the relationship between peer victimization and NSSI among Chinese high school students. We also explored the chain mediating roles of social anxiety and mobile phone addiction and the regulatory role of sex. The findings of this study provide insights for theoretical interventions based on internal mechanisms. Method A self-reported survey of 14,666 high school students from Sichuan County was conducted using a peer victimization scale, NSSI scale, social anxiety scale, and mobile phone addiction scale. A self-administered questionnaire was used to capture sociodemographic information. Results Peer victimization, social anxiety, and mobile phone addiction were positively correlated with NSSI. Peer victimization had significant direct predictive effects on NSSI (95% CI : 0.341, 0.385) and significant indirect predictive effects on NSSI through social anxiety (95% CI : 0.008, 0.019) or mobile phone addiction (95% CI : 0.036, 0.053). Peer victimization had significant indirect predictive effects on NSSI through social anxiety as well as mobile phone addiction (95% CI : 0.009, 0.014). The first stage (predicting the effect of peer victimization on NSSI) and the third stage (predicting the effect of mobile phone addiction on NSSI) were both moderated by sex. Conclusions Peer victimization could directly predict NSSI and indirectly predict NSSI through social anxiety and mobile phone addiction. Thus, social anxiety and mobile phone addiction exhibited chain mediating effects between peer victimization and NSSI in high school students; moreover, sex might be involved in the regulation of the mediation process.

Abstract Purpose To explore (1) the anxiety disorders prevalence, relevant infuencing factors of anxiety disorders; and (2) the current status of social support and quality of life of people with anxiety disorders in the affected areas many years after Lushan earthquake in Ya’an, China.Methods An epidemiological mental health survey was conducted to identify the prevalence of anxiety disorders in general peoples in Ya’an.A multi-stage, group-matching random sampling method was adopted.By face-to-face interviewed,firt stage used the scale for preliminary screening by traned psychiatric nurses,and the second stage used the 5th edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V) for diagnosis by trained Psychiatrists.Results There were 8876 valid questionnaires.The adjusted 12-month and lifetime prevalence of anxiety disorder was 3.83% and 4.44%,respectively.The total scores of SSRS and SF-36 in patients with anxiety disorder were lower than others(all P < 0.05). Regression analysis showed that being female, middle or old, and with chronic physical diseases were risk factors for anxiety disorder, and minority ethnicity, higher education level, and middle or high income were protective factors.Conclusion Though after many years of Lushan earthquake, we also should pay more attention the people of th female, middle or old, with lower education level, lower income level, and chronic physical diseases.

BackgroundCompared with adult-onset schizophrenia， patients with adolescent-onset schizophrenia experience a high genetic susceptibility， severe negative symptoms， high recurrence rate， poor prognosis and social function recovery. And clarifying the brain functional alterations in adolescent-onset schizophrenia is of great significance for further elucidating the pathogenesis of the disease and exploring personalized and precise treatment.ObjectiveTo investigate the altered functional and effective connectivity of bilateral precuneus in first-episode patients with adolescent-onset schizophrenia based on resting-state functional magnetic resonance imaging （rs-fMRI）， thus providing reliable imaging evidence in guiding the study on mechanism involved in adolescent-onset schizophrenia.MethodsTwenty-one drugnaïve first-episode patients with adolescent-onset schizophrenia who met the Diagnostic and Statistical Manual of Mental Disorders， fifth edition （DSM-5） criteria for schizophrenia were enrolled， and another 21 psychiatrially healthy controls matched on age， educational background and gender were concurrently selected. The schizophrenic subjects were evaluated using the Psychotic Symptom Rating Scales （PSYRATS） and Positive and Negative Symptom Scale （PANSS）. All participants underwent rs-fMRI scans， and the whole-brain seed-based functional and effective connectivity analyses were conducted in bilateral cuneus region. Then the correlation between functional connectivity strength and clinical symptoms of patients was discussed.ResultsIn terms of functional connectivity， the functional connectivity of bilateral precuneus and left middle temporal gyrus was increased in patient group compared with healthy control group ［P<0.01， family-wise error （FWE） correction at cluster level， P<0.05］. In terms of effective connectivity， patient group responded to negative feedback with greater activation of seed region and left middle frontal gyrus than healthy control group. Correlation analysis within patient group denoted that the decreased effective connectivity of bilateral precuneus and left middle frontal gyrus was positively correlated with the total PANSS score （r=0.450， P<0.05）.ConclusionThe resting-state functional and effective connectivity of bilateral precuneus is abnormally alerted in drugnaïve first-episode patients with adolescent-onset schizophrenia， and the decreased effective connectivity of bilateral precuneus and left middle frontal gyrus may be related to the development of clinical symptoms. ［Funded by National Key Research and Development Program of China （number， 2022YFC2009901， 2022YFC2009900）］

Objective:To investigate the mediating roles of the fear of missing out and mobile phone addiction between the basic psychological needs satisfaction and phubbing behavior among high school students.Methods:In April 2022, a cross-sectional design survey was conducted on 14 666 high school students. All participants were evaluated by the basic psychological needs scales(BPNS), generic scale of phubbing(GSP), trait-state fear of missing out scale(T-S FOMOS) and mobile phone addiction index(MPAI). The SPSS 26.0 software was used to conduct common method deviation test, descriptive statistics, and correlation analysis.PROCESS 4.1 was used to construct the model, and the Bootstrap method was used to test for mediating effects.Results:(1)Among the 14 036 high school students, there were 1 752 (12.48%) students who were addicted to mobile phones.There were significant differences in gender in the scores including BPNS(boy: 4.43±0.79, girl: 4.36±0.79), GSP(boy: 2.72±1.01, girl: 2.76±1.03) and T-S FOMOS(boy: 1.73±0.60, girl: 1.84±0.64), ( t=5.22, -10.58, -2.78, all P<0.01). Among different grades, there were significant differences in the scores of BPNS, T-S FOMOS, MPAI, and GSP( F=25.43, 39.50, 53.45, 14.59, all P<0.01). (2)Basic psychological needs score were positively correlated with fear of missing out, mobile phone addiction and phubbing( r=-0.432--0.294, all P<0.01). Phubbing were negatively correlated with fear of missing out and mobile phone addiction( r=0.744, 0.538, both P<0.01). Fear of missing out were negatively correlated with mobile phone( r=0.646, P<0.01). (3)The basic psychological needs satisfaction had a direct effect on phubbing behavior, and the effect value was -0.188 (95% CI: -0.173--0.204). The mediating effect of fear of missing out between the basic psychological needs satisfaction and phubbing behavior was -0.035(95% CI: -0.028--0.042). The mediating effect of mobile phone between the basic psychological needs satisfaction and phubbing behavior was -0.203(95% CI: -0.191--0.214). Fear of missing out and mobile phone addiction played a chain mediating role between them, and the mediating effect value was -0.134(95% CI: -0.125--0.143), which accounted for 23.93%(-0.134/-0.560) of the total effect. Conclusion:The high level basic psychological needs satisfaction can alleviate the occurrence of phubbing behavior. It may be achieved by decreasing fear of missing out and reducing mobile phone addiction.

ObjectiveTo investigate the mediating role of loneliness and social anxiety in the relationship between basic psychological needs satisfaction and smartphone addiction among high school students， and to provide references for the intervention to smartphone addiction for high school students.MethodsIn April 2022， a total of 14 666 high school students from 5 middle schools in a county of Sichuan Province were included by random sampling method. Basic Psychological Needs Scales （BPNS）， the UCLA Loneliness Scale-3 edition （UCLA-3）， Interaction Anxiousness Scale （IAS） and the Mobile Phone Addiction Index （MPAI） were used for cross-sectional investigation. Bootstrap method was used to analyze the mediating role of loneliness and social anxiety in the relationship between the basic psychological needs satisfaction and smartphone addiction.Results① In this study， 14 036 valid questionnaires were returned， and 1 752 （12.48%， 95% CI： 0.114~0.136） high school students were found to be addicted to smartphone phone. The BPNS score was negatively correlated with UCLA-3， IAS and MPAI scores （r=-0.771， -0.486， -0.417， P<0.01）. And MPAI score was positively correlated with IAS and UCLA-3 scores （r=0.403， 0.424， P<0.01）. IAS score was positively correlated with UCLA-3 score （r=0.458， P<0.01）. ②The degree of basic psychological needs satisfaction in high school students can directly negatively predict smartphone addiction （β=-0.383， P<0.05）， and can also indirectly affect smartphone addiction through loneliness and social anxiety （β=-0.130， P<0.05）. ③Loneliness （indirect effect value was -0.145） and social anxiety （indirect effect value was -0.074） partially mediate between the basic psychological needs satisfaction and smartphone addiction. Loneliness-social anxiety also has significant chain mediating effect （indirect effect value was -0.034）， which accounted for 8.88%.ConclusionThe basic psychological needs satisfaction can not only directly affect the occurrence of smartphone addiction， but also indirectly affect the occurrence of smartphone addiction through the chain mediation of loneliness and social anxiety.

目的 探究父母低头与青少年手机依赖的关系和孤独感与体育活动在其中的作用机制.方法 于2022年4-5月采用多阶段分层整群抽样法抽取江苏省扬州市和南京市2 233名中学生作为对象,采用手机依赖指数量表(MPAI)、父母低头行为量表(PPS)、UCLA孤独感量表、体育活动等级量表(PARS-3)进行调查,使用蒙特卡罗的贝叶斯估计来分析中介效应,使用依次检验分析被调节的中介.结果 28.71％的青少年存在手机依赖倾向,女生手机依赖发生率高于男生(t=28.777,P＜0.001),高中高于初中(t=8.164,P=0.004);父母低头→孤独感→手机依赖的间接效应=0.083(95％CI:0.066～0.101),中介效应效果量=30.29％;父母低头×体育活动→孤独感的β=-0.115(95％CI:-0.151～-0.079),父母低头×体育活动→手机依赖的β=-0.149(95％CI:-0.186～-0.112),孤独感×体育活动→手机依赖的β=-0.120(95％CI:-0.163～-0.078);体育活动还调节父母低头→孤独感一手机依赖的中介效应(依次检验回归系数检验均有P＜0.001).结论 在父母低头与青少年手机依赖间存在有调节的中介机制,孤独感发挥中介作用,体育活动可调节该中介.

ObjectiveTo clarify the relationship between childhood maltreatment and insomnia in middle school students， and to explore the mediating role of post-traumatic stress disorder （PTSD） symptoms and the moderating role of mental resilience involvement.MethodsFrom April to May 2021， a total of 3 412 students in 3 middle schools in a city in western China were selected using convenient sampling method， and all students were assessed by Childhood Trauma Questionnaire （CTQ）， Post Traumatic Stress Disorder Scale （PCL）， Insomnia Severity Index （ISI） and mental resilience scale. The moderated mediating effect analysis was conducted using Process v3.4.ResultsAmong the middle school students， CTQ scores were positively correlated with PCL and ISI scores （r=0.540， 0.320， P<0.05）， and the scores of CTQ， PCL and ISI were negatively correlated with the score of mental resilience scale （r=-0.049， -0.193， -0.132， P<0.05）. PTSD symptoms exhibited a partial mediating effect on the relationship between general childhood maltreatment and insomnia （β=0.161， P<0.05）， accounting for 80.5% of the total effect.ConclusionAmong the middle school students， the relationship between childhood maltreatment and insomnia is partially mediated via PTSD symptoms， and mental resilience exerts a moderating role between childhood maltreatment and PTSD symptoms.

With the widespread adoption of smartphones， mobile phone addiction among adolescents has emerged as a challenging public health concern. This paper aims to undertake a comprehensive literature review on mobile phone addiction among high school students， both domestically and internationally. It primarily focuses on exploring the conceptual framework， measurement tools， epidemic status， influencing factors and intervention strategies associated with mobile phone addiction in this specific population， so as to provide references for interventions targeting mobile phone addiction among high school students， with the ultimate goal of reducing the incidence rate within this population. ［Funded by Sichuan Provincial Primary Health Development Research Center in 2022， North Sichuan Medical College （number， SWFZ22-C-89）， Mianyang City Social Science Research Key Base-Sichuan Mianyang Minor Psychological Growth Guidance and Research Center 2022 Annual Funding Project （number， SCWCN 2022YB07）］

故意过量服药行为已成为青少年常见的自伤自杀方式之一,女性总的故意过量服药行为人数较男性更多,但男性因故意过量服药行为而死亡的比例较女性更高.故意过量服药行为涉及药物种类较多,常见的药物种类包括解热镇痛药、抗抑郁药、抗精神病药、镇静安眠药等,但不同地区使用率有所不同.故意过量服药行为是多种因素共同作用的结果,其危险因素包括女性、家庭暴力、既往服用药物过量史、多重物质使用、抑郁症、冲动等.故意过量服药行为不仅带来身心健康的损害,同时也增加经济负担.需要对故意过量服药行为的高危人群进行干预,如心理咨询或心理治疗,并加强药物的监管,以此来减少过量服药行为的风险.

ObjectiveTo study the anxiety and depression status of the third-year junior high school students in Nanning city， and to discuss their relationships with test anxiety， so as to provide references for targeted psychological intervention for students.MethodsFrom May to June， 2021， a simple random sampling method was adopted to randomly enroll three classes of third-grade students from one junior high school in each district and county of Nanning city. The selected students were assessed using Test Anxiety Scale （TAS）， Self-rating Anxiety Scale （SAS） and Self-rating Depression Scale （SDS）. Thereafter， Pearson correlation analysis was conducted to explore the correlation among each scale score.ResultsA total of 2 080 students participated in the survey， and 1 826 （87.79%） valid questionnaires were collected. Among them， 999 students （54.71%） felt uncomfortable due to the test. Anxiety and depression were detected in 577 （31.60%） and 830 （45.45%） students， respectively. TAS score of female students was higher than that of male students ［（16.75±6.78） vs. （15.08±6.97）， t=-5.136， P<0.01］， SAS score of female students was higher than that of male students ［（46.05±10.43） vs. （44.16±10.87）， t=-3.769， P<0.01］， and SDS score of female students was higher than that of male students ［（52.34±12.44） vs. （49.98±12.17）， t=-4.039， P<0.01］. Correlation analysis showed that SAS and SDS scores were positively correlated with TAS score （r=0.574， 0.531， P<0.01）， and the correlation still existed after further controlling for age and gender （r=0.570， 0.526， P<0.01）.ConclusionThe third-year junior high school students in Nanning city suffer a high prevalence rate of anxiety and depression， and the two psychological states have positive relations with TAS. Furthermore， both anxiety and depression are more severe in female students than in male students.

Objective:To explore the mediating role of insomnia between childhood trauma and suicide risk in middle school students.Methods:Childhood trauma questionnaire(CTQ), insomnia severity index(ISI) and suicidal behaviors questionnaire-revised(SBQ-R) were used to investigate 3 442 middle school students.According to the total score of the SBQ-R, those who scored less than or equal to 6 were divided into low suicide risk group, and those who scored more than or equal to 7 were divided into high suicide risk group.In this study, there were 2 168 students in the low suicide risk group and 1 274 students in the high suicide risk group.SPSSAU 21.0 online statistical software was used for common method deviation test, descriptive statistics, variance analysis and correlation analysis, and structural equation model was constructed, and Bootstrap method was used for mediation effect test.Results:(1) There were statistically significant differences between the high suicide risk group and the low suicide risk group in terms of grade and gender( χ2=11.144, 83.737, both P<0.05), and there were statistically significant differences in the types of childhood trauma and the severity of insomnia( χ2=292.211, 333.998, both P<0.05). (2) The total score of childhood trauma in the high suicide risk group (43.92±10.50) was higher than that in the low suicide risk group (37.74±6.93) ( F=351.78, P<0.01), and the score of insomnia in the high suicide risk group (10.66±5.54) was higher than that in the low suicide risk group (7.04±4.76) ( F=379.25, P<0.01). (3)The total score of childhood trauma was positively correlated with the score of suicide risk ( r=0.415, P<0.01), and the total score of childhood trauma was positively correlated with the score of insomnia ( r=0.306, P<0.01), and the score of insomnia was significantly positively correlated with the score of suicide risk ( r=0.399, P<0.01). After controlling for demographic data, anxiety and depression, the correlation was still significant ( P<0.01). (4) Path analysis and mediation test showed that childhood trauma had a positive effect on insomnia ( β=0.30, P<0.01), insomnia had a positive effect on suicide risk ( β=0.29, P<0.01), and childhood trauma had a positive effect on suicide risk ( β=0.33, P<0.01). The mediating effect of insomnia accounted for 21.21% of the total effect.After controlling for demographic data, anxiety and depression, the mediating effect accounted for 10.66% of the total effect. Conclusion:Childhood trauma and insomnia have a significant impact on the suicide risk among middle school students.Insomnia plays a partial mediating role between childhood trauma and middle school students' suicide risk.Timely management of the sleep disturbances of traumatized individuals can reduce the suicide risk among middle school students.

抑郁症作为一种高发精神疾病,其评估主要依赖患者的临床症状,为提升对这种高发精神疾病的临床干预效果,许多研究者开始寻找可测量的生物标志物.事件相关电位(ERP)作为一种电生理学指标,非常适合对抑郁症患者进行个体化神经认知评估,其中失匹配负波(MMN)和P300是目前研究较多的ERP成分.MMN是一种负向的潜伏期为150～250 ms的ERP成分,能反映前注意加工过程,其神经发生源位于初级听觉皮层和前额叶皮层.MMN振幅下降、潜伏期延长有助于抑郁症的诊断,且与抑郁程度具有相关性,能够反映抗抑郁疗效,可能是抑郁症和双相情感障碍鉴别诊断的生物标志物.P300是由刺激诱发的潜伏期约300 ms的晚期正向波,P300振幅和潜伏期提供了记忆、注意和心理处理速度等认知过程信息.P300振幅的降低反映了抑郁症患者广泛的认知障碍,可提高抑郁症的诊断正确率,还可在一定程度上反应抗抑郁疗效,可能是区分重度抑郁症和双相情感障碍的潜在生物标志物.

Purpose: Post-stroke depression (PSD) is the most common psychiatric sequelae of stroke. Numerous studies revealed that event -related potentials (ERP) can reflect depression severity to a certain extent, while there is almost no research on depression after hemorrhagic stroke. Therefore, we employed a prospective cross-sectional study to explore the relationship between ERP and depression after hemorrhagic stroke.Methods: A total of 74 patients with intracranial hemorrhage were included in this study. Neurological deficits were evaluated using the National Institutes of Health Stroke Scale (NIHSS) on admission. Depression severity and cognitive impairment were measured using the 17-item Hamilton Depression Scale (HAMD-17) and the Chinese version of the Montreal Cognitive Assessment (MoCA) after two weeks of treatment. All patients were conducted auditory Oddball paradigm for event-related potential mismatch negativity (MMN) and P300.Results: In total, 36 patients were diagnosed with PSD at the two weeks of treatment, for a percentage of 48.6%. Depression severity of ICH patients correlated positively with both the latency of MMN (r = 0.376, P = 0.001) and P300 (r = 0.325, P = 0.005), and correlated negatively with both the amplitude of MMN (r=-0.385, P = 0.001) and P300 (r=-0.311, P = 0.007). Depression severity was negatively correlated with cognitive function after hemorrhagic stroke (r=-0.347, P = 0.002).Conclusion: The latency and amplitude of MMN and P300 can well reflect the degree of depression after hemorrhagic stroke, which may help in the early diagnosis and effective treatment of PSD.

目的 探讨中学生童年创伤和失眠与非自杀性自伤(NSSI)的关系,以及失眠在中学生童年创伤与非自杀性自伤间的中介效应.方法 采用童年创伤问卷、失眠严重程度指数、青少年自我伤害问卷对广西南宁市三所中学的学生进行抽样调查,采用SPSSAU 21.0进行统计分析.结果 在3 442名中学生中,NSSI的检出率为31.93％,在年级、性别、家庭经济状况三方面NSSI检出率差异有统计学意义(x2=38.841,P＜0.001;x2=10.524,P=0.001;x2=16.486,P＜0.001);伴NSSI组童年创伤总分及各维度得分、失眠总分高于不伴NSSI组(F值分别为249.029、138.256、65.656、23.316、90.787、279.991、386.503,均P＜0.001);童年创伤与 NSSI 和失眠均呈正相关(r=0.126～0.328,P＜0.010;r=0.113～0.307,P＜0.010),失眠与NSSI呈正相关(r=0.355,P＜0.010),控制人口学资料后相关性仍然存在;控制人口学资料后,童年创伤对NSSI的总效应为0.514(95％CI:0.466～0.562),对失眠的直接效应为0.183(95％CI:0.164～0.202),失眠对NSSI的直接效应为0.634(95％CI:0.552～0.715);失眠在童年创伤与NSSI间的中介效应为0.116(95％CI:0.081～0.153),说明失眠在中学生童年创伤与NSSI间起部分中介作用,中介效应占总效应的比例为22.568％.结论 童年创伤既可以直接影响中学生非自杀性自伤行为,也可以通过失眠的中介效应间接影响中学生非自杀性自伤行为.

目的:了解体检人群高血压检出情况,为高血压的防治提供参考.方法:选取2019-2021年在成都市某三级甲等医院体检且年龄≥18岁的25 064例健康体检者作为研究对象,收集一般人口学资料、体格检查及实验室检查指标,筛选高血压疾病发生的危险因素,构建风险预测模型.结果:25 064例健康体检者中,高血压检出率为11.7％.二元Logistic回归分析显示,工作状况为在职、奶制品摄入充足为高血压的保护因素(OR=0.681、0.582,P＜0.05),年龄增长、有高血压家族史、饮酒、血脂异常、超重或肥胖、冠心病为高血压的独立危险因素(OR=3.319、5.765、20.276、4.461、1.486、1.514、2.713、2.894,均P＜0.05).疾病风险模型中各因素赋分如下:工作状况为在职1分,年龄40～＜60岁3分、60～＜80岁5分、≥80岁8分,有高血压家族史4分,奶制品摄入充足1分,饮酒1分,血脂异常1分,超重或肥胖3分,有冠心病4分.构建的风险预测模型预测高血压的受试者工作特征(ROC)曲线下面积(AUC)为0.864(95％CI:0.861～0.872),灵敏度、特异度分别为0.968和0.496.结论:构建高血压疾病预测模型对健康体检人群具有较好的预测能力,风险评估模型可以准确地预测高血压发病情况.