Prevention -Obesity 915 >1500 MASL, vs 19

The advent of percutaneous coronary intervention (PCI) transformed the treatment of obstructive coronary artery disease (CAD) by creating a less invasive revascularization option to coronary-artery bypass grafting (CABG). 1 Although, randomized controlled clinical trials (RCTs) are the gold standard in medical research, there is not always the possibility to conduct properly designed RCTs. The gap between evidence from RCTs and clinical practice can be filled by epidemiological studies and properly designed registries. 2 The results of the Hellenic Heart Registry on Percutaneous Coronary Interventions (HHR-PCI), a national registry of patients with stable angina or acute coronary syndromes who underwent PCI, were only recently published. 3 The purpose of the current study is to report the experience of a newly formed Catheterization laboratory at a tertiary hospital of Athens and to compare its findings to those reported by the HHR-PCI... (excerpt)

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Papadimitriou D, Gavrielatos G, Stougiannos P, Kaplanis I, Trikas A. Primary left main coronary artery thrombus aspiration as a standalone treatment: sailing in uncharted waters. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej. 2016;12(3):258-261. doi:10.5114/aic.2016.61649. APA Papadimitriou, D., Gavrielatos, G., Stougiannos, P., Kaplanis, I., & Trikas, A. (2016). Primary left main coronary artery thrombus aspiration as a standalone treatment: sailing in uncharted waters. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej, 12(3), 258-261. https://doi.org/10.5114/aic.2016.61649 Chicago Papadimitriou, Dimitra, Gerasimos Gavrielatos, Pavlos Stougiannos, Ioannis Kaplanis, and Athanasios Trikas. 2016. "Primary left main coronary artery thrombus aspiration as a standalone treatment: sailing in uncharted waters". Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej 12 (3): 258-261. doi:10.5114/aic.2016.61649. Harvard Papadimitriou, D., Gavrielatos, G., Stougiannos, P., Kaplanis, I., and Trikas, A. (2016). Primary left main coronary artery thrombus aspiration as a standalone treatment: sailing in uncharted waters. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej, 12(3), pp.258-261. https://doi.org/10.5114/aic.2016.61649 MLA Papadimitriou, Dimitra et al. "Primary left main coronary artery thrombus aspiration as a standalone treatment: sailing in uncharted waters." Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej, vol. 12, no. 3, 2016, pp. 258-261. doi:10.5114/aic.2016.61649. Vancouver Papadimitriou D, Gavrielatos G, Stougiannos P, Kaplanis I, Trikas A. Primary left main coronary artery thrombus aspiration as a standalone treatment: sailing in uncharted waters. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej. 2016;12(3):258-261. doi:10.5114/aic.2016.61649.

Lycopene, a carotenoid, is known for its antioxidant properties. Little is known, though, about the relationship of dietary tomato-juice intake and risks factors, like inflammation, insulin resistance and hyperlipidemia, implicated in metabolic syndrome. In the present study, we examined whether supplementation with tomato-juice has any implication on the risk status of patients with metabolic syndrome. A comparative study was conducted in 27 individuals diagnosed with metabolic syndrome. Fifteen of them were instructed to use commercially available tomato-juice as refreshment 4 times a week over a period of two months and twelve individuals served as the control group. Several parameters reflective of the metabolic syndrome were monitored both in the group supplemented with tomato juice and in the control group (ADMA for entdothelial function, TNF-α and IL-6 for inflammation, FIRI for insulin resistance). There was a significant improvement in the inflammation status and the endothelial dysfunction of the tomato-juice supplemented patients. At the same time, insulin resistance improved and a pronounced decrease in LDL was recorded, along with a slight increase in HDL. The results of the present study suggest an alleviating effect of tomato-juice with regard to risk factors associated with metabolic syndrome.

Metabolic syndrome (MS) is a constellation of metabolic derangements associated with vascular endothelial dysfunction and oxidative stress and is widely regarded as an inflammatory condition, accompanied by an increased risk for cardiovascular disease. The present study tried to investigate the implications of telomerase activity with inflammation and impaired endothelial function in patients with metabolic syndrome. Telomerase activity in circulating peripheral blood mononuclear cells (PBMC), TNF-α, IL-6 and ADMA were monitored in 39 patients with MS and 20 age and sex-matched healthy volunteers. Telomerase activity in PBMC, TNF-α, IL-6 and ADMA were all significantly elevated in patients with MS compared to healthy volunteers. PBMC telomerase was negatively correlated with HDL and positively correlated with ADMA, while no association between TNF-α and IL-6 was observed. IL-6 was increasing with increasing systolic pressure both in the patients with MS and in the healthy volunteers, while smoking and diabetes were positively correlated with IL-6 only in the patients' group. In conclusion, in patients with MS characterised by a strong dyslipidemic profile and low diabetes prevalence, significant telomerase activity was detected in circulating PBMC, along with elevated markers of inflammation and endothelial dysfunction. These findings suggest a prolonged activity of inflammatory cells in the studied state of this metabolic disorder that could represent a contributory pathway in the pathogenesis of atherosclerosis.