PurposeTo describe demographic and clinical characteristics of patients with graft failure after keratoplasty, determine the cause of graft failure and outcomes.MethodsThe charts of patients between 2008-2013 in the Cornea Service at Wills Eye Hospital with a history of a corneal transplant before the end of 2012 were retrospectively reviewed. Included were patients who had graft failure after corneal transplantation and had at least one year of follow-up after transplantation. Penetrating keratoplasty (PK) and Descemet's stripping endothelial keratoplasty (DSEK) patients were analyzed separately.ResultsA total of 186 eyes of 170 patients with graft failure after a PK (156) or DSEK (30) procedures were identified. The baseline characteristics included 100 female and 70 male patients with an age between 0 and 90 years (median 63 years). At the time of surgery, 38% had three or more systemic diseases and 68% were using three or more systemic medicines. Mean follow up time for PK was nearly four times of DSEK. Only 2 DSEK eyes (7%) underwent a 3rd DSEK graft, while 47 (30%) PK eyes underwent a 3rd PK and 15 (10%) PK eyes underwent more than three PK procedures.ConclusionsMost DSEK failures occurred in 1st year, while graft failure in PKs is scattered over years. Failure in DSEK is mostly due to graft or surgical risk factors but in PK mostly due to factors in the host. DSEK does not appear to be as affected by the patients' demographic and clinical characteristics as much as PK.

Purpose: To compare the surgical outcomes of Muller muscle conjunctival resection (MMCR) and levator advancement (LA) in patients with mild to moderate blepharoptosis. Methods: A retrospective review of patients who underwent surgery for mild to moderate ptosis between 2015 and 2020 was performed. The degree of ptosis was graded based on the amount of upper eyelid drooping: mild ≤ 2 mm and moderate < 4 mm. Surgical success was defined as post-operative marginal reflex distance 1 (MRD1) ≥ 4.0 and ≤ 5.0 mm, and a satisfactory eyelid contour. Results: A total of 82 eyes of 65 patients underwent ptosis repair surgeries. MMCR was performed in 48 eyes and LA in 34 eyes. Under-correction was detected in 8.3% and 11.8% of the patients in MMCR group and LA group respectively. There was no patient with over-correction in the MMCR group postoperatively, 3 patients in the LA group had over-correction (0% vs. 8.8% respectively). The success rate in our study was found to be 91.7% in the MMCR group and 72.2% in the LA group. Conclusions: The MMCR and LA procedures are effective approaches in treating patients with mild to moderate eyelid ptosis in our population. Each procedure had its superiority in selected groups of patients. However, the complication rate and duration of surgery were found to be lower in MMCR group. Abbreviations: LA = Levator Advancement, LF = Levator Function, MMCR = Muller Muscle Conjunctival Resection, MRD 1 = Marginal Reflex Distance.

AMAÇ: Glukokinaz (GCK) gen mutasyonu pozitif olan Genç Erişkin Dönemde Başlayan Diyabet (Maturity Onset Diabetes of Young - MODY) tanısı alan olgularla sağlıklı bireylerin koroid tabakası kalınlıklarının karşılaştırılması amaçlandı.GEREÇ VE YÖNTEM: MODY tanısı GCK gen mutasyonu bakılarak doğrulanmış olan ama diyabetik retinopatisi olmayan 30 hasta (MODY grubu) ve 30 sağlıklı kişi (kontrol grubu) çalışmaya dahil edildi. Kontrol grubu, MODY grubu ile yaş, cinsiyet, refraktif kusur ve aksiyel uzunluk açısından uyumlu seçildi. Koroid kalınlığı hastaların sağ gözünde foveada, foveadan 1500 μm ve 3000 μm uzaklıklarda nazalde ve temporalde RTVue-100 Fourier-domain optik koherens tomografi (OKT) kullanılarak ölçüldü.BULGULAR: MODY tanı zamanı 4.1±5.8 yıl (aralık; 0-17 yıl) idi. Ortalama HBa1c düzeyi 5.1 (aralık: 4.4-6.2, referans aralık: 4-6) iken hiçbir hastada diyabetik retinopati yoktu. Ortalama subfoveal koroid kalınlığı subfoveal alanda MODY grubunda 370.09± 86.66 μm iken kontrol grubunda 354.44 ± 76.70 μm idi (p=0.456). Koroid kalınlığı nazal 1500 μm’de (sırasıyla 300.75 ± 67.02 ve 296.13 ± 73.45 μm, p=0.672), nazal 3000 μm’de (184.56 ± 45.53 ve 192.94 ± 57.63 μm, p=0.485), temporal 1500 μm’de (325.16 ± 59.41 ve 299.59 ± 67.81 μm, p=0.093) ve temporal 3000 μm’de (261.88 ± 43.30 ve 256.75 ± 50.83 μm, p=0.582) istatistiksel anlamlı değişiklikler göstermedi.SONUÇ: Literatürde diyabetin koroid üzerine etkilerini araştıran birçok çalışma olmasına rağmen, bu çalışma spesifik olarak MODY’li hastalarda koroid kalınlığının değerlendirildiği ilk çalışmadır. Diyabetik retinopatisi olmayan MODY’li hastalarda koroid kalınlığı etkilenmeyebilir. Bu MODY’li hastaların genç olmasına, MODY süresinin kısa olmasına ve diyabet regülasyonunun iyi olmasına bağlanabilir.

AMAÇ: Glukokinaz (GCK) gen mutasyonu pozitif olan Genç Erişkin Dönemde Başlayan Diyabet (Maturity Onset Diabetes of Young - MODY) tanısı alan olgularla sağlıklı bireylerin koroid tabakası kalınlıklarının karşılaştırılması amaçlandı.GEREÇ VE YÖNTEM: MODY tanısı GCK gen mutasyonu bakılarak doğrulanmış olan ama diyabetik retinopatisi olmayan 30 hasta (MODY grubu) ve 30 sağlıklı kişi (kontrol grubu) çalışmaya dahil edildi. Kontrol grubu, MODY grubu ile yaş, cinsiyet, refraktif kusur ve aksiyel uzunluk açısından uyumlu seçildi. Koroid kalınlığı hastaların sağ gözünde foveada, foveadan 1500 μm ve 3000 μm uzaklıklarda nazalde ve temporalde RTVue-100 Fourier-domain optik koherens tomografi (OKT) kullanılarak ölçüldü.BULGULAR: MODY tanı zamanı 4.1±5.8 yıl (aralık; 0-17 yıl) idi. Ortalama HBa1c düzeyi 5.1 (aralık: 4.4-6.2, referans aralık: 4-6) iken hiçbir hastada diyabetik retinopati yoktu. Ortalama subfoveal koroid kalınlığı subfoveal alanda MODY grubunda 370.09± 86.66 μm iken kontrol grubunda 354.44 ± 76.70 μm idi (p=0.456). Koroid kalınlığı nazal 1500 μm’de (sırasıyla 300.75 ± 67.02 ve 296.13 ± 73.45 μm, p=0.672), nazal 3000 μm’de (184.56 ± 45.53 ve 192.94 ± 57.63 μm, p=0.485), temporal 1500 μm’de (325.16 ± 59.41 ve 299.59 ± 67.81 μm, p=0.093) ve temporal 3000 μm’de (261.88 ± 43.30 ve 256.75 ± 50.83 μm, p=0.582) istatistiksel anlamlı değişiklikler göstermedi.SONUÇ: Literatürde diyabetin koroid üzerine etkilerini araştıran birçok çalışma olmasına rağmen, bu çalışma spesifik olarak MODY’li hastalarda koroid kalınlığının değerlendirildiği ilk çalışmadır. Diyabetik retinopatisi olmayan MODY’li hastalarda koroid kalınlığı etkilenmeyebilir. Bu MODY’li hastaların genç olmasına, MODY süresinin kısa olmasına ve diyabet regülasyonunun iyi olmasına bağlanabilir.

Recently; contact lenses (CL) are widely used for correct refractive errors; therapeutic reasons such as keratoconus, epithelial defects, and for cosmetic reasons. Despite the advances in contact lens technology, serious complications related to contact lenses can be seen due to poor patient compliance and lack of contact lens training during the examination. Serious complications can be seen if contact lenses are worn without following the hygiene rules, especially in female patients after the use of cosmetics In order to prevent all these, it is important to inform the patients well in course of the examination. In this study, it is aimed to discuss toxic keratoconjunctivitis and its treatment in a patient who has worn contact lenses without washing her hands after extensive cosmetic use.

To examine ocular surface changes in patients with maturity-onset diabetes of young (MODY). Fifty patients with MODY who were transferred to Genetic Diagnosis Department of Diskapi Yildirim Beyazit Training and Research Hospital have been included. All patients were subjected to Ocular Surface Illness Index (OSDI) survey, shirmer test, invasive and non-invasive tear break up time (TBUT), cornea fluorescein, and Lissamine green dye tests. Lastly, meibography measurements have been completed using Sirius Scheimpflug camera (Sirius, CSO, Florence, Italy). All 50 patients had a glucokinase (GCK) mutation. MODY diagnosis time was 5.0 ± 5.5 years (range: 0–20 years) on an average. While the average HBa1c levels were 5.5 (range: 4.8–6.5, reference range: 4–6), none of the patients were diagnosed with diabetic retinopathy in fundus examination. There was no significant difference between MODY and control group in terms of OSDI score, Schirmer 1 test, meibomian gland loss, average BUT, TBUT ((p)0.05). Our work is the first one which specifically evaluates ocular surface in MODY patients. Contrary to the common concept that “dry eye is frequently seen in type 1 and type 2 DM,” we did not come across any significant difference between MODY and control group in ocular surface tests. It might be linked to the fact that not enough time had passed for DR or DES symptoms to be detected. Our patients’ average diabetes diagnosis length might be a short time span for clinical symptoms like DR and DES to show up.

Pellucid marginal degeneration (PMD) is a non-inflammatory progressive ectatic disorder of the cornea. It has similar features with other ecstatic diseases like keratoconus and keratoglobus but location in the cornea shows difference. Typical location of the PMD is the inferior quadrant of the cornea, but it may rarely develop in the superior quadrant. Here we present clinical finding and treatment of a reverse PMD case. 60 years-old male had bilateral low vision. Vision loss was begun 5 years after cataract operation. There were bilateral high astigmatism and PMD in superior quadrant of the corneas of the both eyes. Vision of the patient increased with sclera contant lens application.

Amaç: Ailesel Akdeniz ateşi (AAA) olan hastalarda oküler yüzeyi değerlendirmektir. Gereç ve Yöntemler: Bu çalışmada, Haziran 2013-Haziran 2015 tarihleri arasında Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi Genetik Tanı Merkezine yönlendirilen AAA hastaları çalışmaya alındı. Oküler yüzey değişiklikleri; oküler yüzey hastalık indeksi (OYHİ) anketi, Schirmer testi, gözyaşı kırılma zamanı (GKZ), oküler yüzey boyama paterni ve meibografi ile değerlendirildi. Bulgular: Ortalama yaş 88 AAA hastasında (grup 1) 35,1±13,1 yıl (67-10) iken, 31 kontrol hastasında (grup 2) 34,6±12,7 yıl idi (66-11). OYHİ skoru grup 1'de 28,75±18,47 iken, grup 2'de 17,63±15,37 idi (p=0,03). Meibomian bez (MB) kaybı grup 1'de grup 2'den daha fazlaydı (sırasıyla %14,7±11,9 ve %9,9±8,9). Schirmer testi AAA grubunda kontrol grubuna göre daha kısa bulundu (sırasıyla 20,82±9,94 ve 26,03±8,28 mm). Grup 1'de ortalama GKZ 6,53±3,7 (1-15) iken, kontrol grubunda 11,64±2,97 (5-15) idi (p=0,0001). Ortalama fluoreseinle kornea boyanma skoru grup 1 ve 2'de sırasıyla 2,78±2,89 ve 0,19±0,4 idi. Ortalama Lisamin yeşili boyanma skoru grup 1'de 1,87±1,91 iken, grup 2'de 0,22±0,49 idi. Yeni AAA tanısı alan/kolşisin kullanmayan AAA'lı 26 hastayla önceden AAA tanısı konulmuş/kolşisin kullanan 62 hastanın oküler yüzeyinin değerlendirildiği test sonuçları benzer olarak saptandı. Homozigot M694V mutasyonu olan (16 hasta) ve olmayan (72 hasta) AAA hastaları karşılaştırıldığında, oküler yüzeyi değerlendirilen test sonuçları benzerdi. Sonuç: AAA hastalarındaki Akdeniz ateşi gen mutasyonu sonucu gelişen kontrol edilemeyen inflamasyonun hem MB kaybına neden olup gözyaşı buharlaşmasını artırarak hem de gözyaşı üretimini azaltarak kuru göze neden olabileceği düşünülmektedir. Çalışmamızda, M694V homozigot mutasyonunun ve kolşisinin oküler yüzeye önemli bir etkisinin olmadığı saptanmıştır.

OZET Kronik plak psoriazis hikayesi olan 62 yasindaki erkek hasta Turk hamaminda kese yaptirdiktan hemen sonra baslayan ve tum vucudu kaplayan yanma, kasinti ve pul pul eritematoz plak sikâyetiyle geldi. Psoriazis disinda sistemik veya okuler hastalik hikayesi yoktu. Hastanin oykusunde Turk hamaminda kese yapilmasina bagli olusan travma disinda presipite edici bir faktor saptanmadi. Hasta gozlerinde yanma, batma, sulanma, yabanci cisim hissi ve kizariklik sikâyetiyle goz klinigine basvurdu. Gorme keskinligi her iki gozde 10/10 idi ve fundus muayenesi dogaldi. Bilateral alt kapaklarda ektropion ve korneada yuzeysel noktasal erozyonlar mevcuttu. Cildin asiri kuru ve gergin oldugu izlendi. Travma sonrasi tum vucut alanini kaplayan asiri kuruluk, pullanmalar ve eritem gibi klinik bulgulara dayanarak eritrodermik psoriazis tanisi kondu ve cilt biyopsisi ile dogrulandi. Hastanin dermatolojik tedavisinde topikal kalsipotriol, topikal kortikosteroid ve nemlendiriciler kullanilirken, gozundeki lezyonlar icin koruyucu icermeyen goz yasi ve goz jeli kullanildi. Hastada 12 haftada total remisyon gozlendi. Anahtar Sozcu¨kler: Psoriazis; Ektropion; Eritrodermik psoriazis ABSTRACT We present a 62-year-old man with a history of chronic plaque psoriasis presented with scaly erythematous plaques with itching and burning that covered his entire body immediately after rubbing with a coarse bath-glove in a Turkish bath. He had no systemic and ocular disease history except psoriasis. No history or clinical evidence of precipitating factors except trauma was detected. The patient referred to our ophthalmology clinic with complaints of foreign body sensation and watering in his eyes. Visual acuity was 10/10 and intraocular and fundus examinations were normal. There were bilateral lower lid ectropion and superior punctate erosions on cornea. A diagnosis of erythrodermic psoriasis was made based on the clinical findings and was confirmed by skin biopsy. Patient was then treated with topical salicylic acid, calcipotriene for skin lesions, preservative free lubricants and jells for ocular lesions for 12 weeks with complete remission. Keywords: Psoriasis; Ectropion; Eritrodermic psoriasis

INTRODUCTION: To examine the repeatability of central corneal thickness (CCT) measurements by corneal dynamic Scheimpflug analyzer Corvis ST (Corvis), RTVue anterior segment optical coherence tomography (OCT) and Sirius corneal topography (Sirius) in normal eyes and compare the agreement of devices with each other. METHODS: Forthy right eyes of 40 patients were included in the study. Patients with active ocular pathology and a history of ocular trauma were excluded. All measurements were performed from 12: 00 to 15: 00 by the same physician. RESULTS: The mean age of the subjects was 35,5+-2,3 and 22 were males and 18 were females. Interclass correlation coefficient was 0.993 for Corvis, 0,998 for OCT and 0.990 for Sirius. CCT was 8,4u thinner in OCT compared with CORVIS and 4,0u thinner compared with Sirius. Limits of Agreement (LoA) of devices was -6,7 to 14.7u for Corvis and Sirius, -25.6u to 8.8u for Corvis and OCT, -19.9 to 13.0u for Sirius and OCT. Two devices which had the narrow LoA (which means the best agreement with each other) were Sirius and Corvis. DISCUSSION AND CONCLUSION: It has been observed that repeatibility of all three devices were very good for CCT measurement. Agreement of Sirius and Corvis was better when compared with other devices. Thus, Corvis and Sirius can be alternatively used in clinical practice. Since measurements performed by OCT were thinner than other devices, OCT can be used in clinical practice when minor changes are critical in CCT measurement.

Purpose: Ectodermal dysplasia (ED) results from abnormal development of the ectodermal layer. Although coexistence of ED and retinal pathology has been described, concomitance with retinal venous tortuosity has not been reported in the literature. Methods: Case report. Results: We report the case of a 23-year-old man with ED with bilateral retinal venous tortuosity, trichomegaly, meibomian gland dysfunction, and dry eye. Although the coexistence of ED with trichomegaly and meibomian gland dysfunction has been previously reported, to the best of our knowledge, this is the first reported case of retinal venous tortuosity associated with ED. Conclusion: Coexistence of retinal venous tortuosity and ED may be the consequence of a genetic mutation affecting cellular signaling pathways during retinal angiogenesis.

Objective: To evaluate the association between uveitis and Familial Mediterranean Fever (FMF). Material and Methods: This retrospective study was performed to evaulate the prevalence of uveitis in patients with FMF referred to Genetic Diagnostic Center at Diskapi Yildirim Beyazit Training and Research Hospital from June 2011 to June 2015. We included all 132 patients with FMF. Results: Four of the 132 patients with FMF had uveitis. Three of the 4 patients had anterior uveitis, and 1 had posterior uveitis. One of the patients with anterior uveitis also had a history of recurrent episcleritis. All 4 patients with FMF and uveitis have been on Colchicine. Two of the 29 patients (6,9%) with a heterozygous mutation (E148 and M694V), 1 of the 35 patients (2.9%) with a homozygous mutation (M694V/M694V), 1 of the 51 patients (2%) with a compound heterozygous mutation (M694V/M680I) had uveitis. None of the 17 patients without a Mediterranean fever (MEFV) gene mutation had uveitis. The prevalence of uveitis in the FMF patients (3.1%) was significantly higher than the highest prevalence of uveitis reported in the literature (0.12%). In our study, FMF was a predisposing factor in the development of uveitis [odds ratio: 26 (95% CI: 8.3-81.3)], especially in patients with M694V mutations [odds ratio: 33.8 (95% CI: 9.3-122.1)]. Although 2 of the 4 patients with uveitis had hypertension and asthma, none had any systemic diseases predisposing to uveitis. Conclusion:MEFV gene mutations, particularly in M694V mutations, may be a predisposing factor in the development of uveitis.

This study was aimed to assess the long-term results of phacoemulsification and posterior chamber intraocular lens implantation in patients with anterior uveitis.

Yirmi bir yaşındaki kadın olgu, sol çene cerrahisi sonrası akut olarak başlayan sağ trigeminal sinir dermatomunda kirpiklerde ve kaşta beyazlama şikâyetiyle geldi. Hastanın hikâyesinde sistemik veya oküler herhangi bir hastalığı bulunmamaktaydı. Ailesinde poliozis öyküsü yoktu ve sistemik veya topikal ilaç kullanmamaktaydı. Yapılan muayenesinde sağ tarafta trigeminal sinirin 1. dermatomunda kirpiklerde ve kaşta poliozis izlenirken, olgunun sol kaşını periferik fasiyal paraliziye bağlı kaldıramadığı ve sol trigeminal sinir dermatomunda duyu hissinin azaldığı gözlemlendi. Göz muayenesi tamamen normaldi. Olgunun beyin manyetik rezonans ve temporomandibuler manyetik rezonans görüntülemesinde herhangi bir patolojiye rastlanmadı ve kan testleri tamamen normaldi. Altı aylık takip sonunda, poliozisin daha fazla yayılmaksızın kirpiklere ve kaşlara lokalize olduğu izlendi. Bu olgu, cerrahi travma sonrası akut segmental poliozisin rapor edildiği literatürdeki ilk vakadır.

PURPOSE:We aimed to evaluate changes in retinal, choroidal, ganglion cell complex (GCC) and retinal nerve fiber layer (RNFL) thicknesses in genetically diagnosed adult patients with familial Mediterranean fever (FMF).METHODS:A total of 50 eyes of 50 genetically diagnosed patients with FMF and 50 eyes of controls were analyzed. Patients were recruited from the Genetic Diagnostic Center of Dışkapı Yıldırım Beyazıt Research and Training Hospital, Turkey. Retinal and choroidal thicknesses were obtained using spectral-domain optical coherence tomography from choroid, retina, GCC, and RNFL.RESULTS:Average baseline choroidal thickness was statistically significantly thinner in patients with FMF than controls at Ccenter (325.85 ± 30.8 µm and 338.97 ± 23.9 µm, respectively, p = 0.038), Cnasal500 (328.77 ± 31.6 µm and 349.00 ± 23.3 µm, respectively, p = 0.002), Cnasal1000 (324.97 ± 33.6 µm and 351.23 ± 23.8 µm respectively, p = 0.0001) and Cnasal1500 (324.75 ± 37.1 µm and 344.61 ± 27.3 µm, respectively, p = 0.008). However, there was no significant difference in temporal choroidal thickness (Ctemporal500, Ctemporal1000 and Ctemporal1500) in patients with FMF compared to controls (p > 0.05). There were no significant differences in retinal, GCC and RNFL thicknesses between the groups (p > 0.05).CONCLUSION:We hypothesize that the chronic inflammation seen in FMF could be the reason for the reduction seen in choroidal thickness in adult patients with FMF. Retinal, GCC and RNFL thicknesses did not differ from controls.

AIM:To describe a modified split-conjuctival autograft technique for double-head pterygium and evaluate the postoperative outcomes.METHODS:A retrospective analysis of all patients who underwent split-conjunctival autograft surgery for double-head pterygium from November 2012 to March 2014. Conjunctival autograft was split vertically, in order to obtain limbal sides of cojunctival autograft for both sides. No adjunctive agent was used. Records of included patients were reviewed and outcomes and recurrence rates were noted.RESULTS:Eight cases of double-head pterygia were noted in 158 total cases of pterygia evaluated (5%). The baseline characteristics included 2 female and 6 male with an age between 26 and 71 (average 42.63) years. All eyes had 12-month follow-ups in average (6-21 months). No intraoperative or postoperative complications were noted. No recurrence was observed.CONCLUSION:A modified, vertical-split conjunctival autograft without any adjunctive agents is a successful and safe technique in management of double-head pterygium.

Purpose: To evaluate the association between diabetes mellitus (DM) and presence and severity of Herpes simplex eye disease (HSED). Methods: We conducted two sub-studies. We included the patients seen on the Cornea Service of the Wills Eye Hospital from January 2008 to August 2012. Study 1 included 541 patients with HSED and 3226 controls. Study 2 involved 40 diabetic and 120 non-diabetic ocular surface HSED patients. Severity of ocular surface HSED was graded as mild, moderate, or severe, based on best-corrected visual acuity (BCVA). Patients were excluded if they had fewer than two office visits or had non-Herpes simplex-related vision-threatening conditions. Diabetes was graded as: diet group (DM controlled with diet), oral group (DM controlled with oral medications), and insulin group (DM control required insulin). Results: Five of 541 (0.93%) HSED patients had type 1 DM, similar to 19/3246 (0.59%) controls (p = 0.375); 48 of 541 (8.88%) HSED patients had type 2 DM, similar to 287/3246 (8.84%) controls (p = 0.981). Using multinomial logistic regression analyses, the probability/risk of being in the severe ocular surface HSED group as opposed to the mild ocular surface HSED group were not statistically significantly different between DM patients and those without DM (p = 0.120; OR, 1.900; 95% CI, 0.846-4.266). Conclusions: There may not be a positive association between type 2 DM and HSED.

Amaç: İlkokul öğrencilerinden oluşan bir örneklemde göz sağlığı taraması sonuçlarını değerlendirmektir. Gereç ve Yöntemler: Ankara ilinde, bir ilköğretim okulunda öğrenim gören tüm öğrencilere göz sağlığı taraması yapıldı. Öğrencilere görme keskinliği, örtme testi, göz hareketleri, ön ve arka segment muayenelerini kapsayan tam oftalmolojik muayene yapıldı. Tedavi gerektiren çocuklar ilgili göz birimlerine yönlendirildi. Bulgular: Yaş ortalaması 7.36±1.50 yıl olan 686 çocuğun göz sağlığı taraması yapıldı. Cinsiyet dağılımı 326 (%47,5) kız ve 360 (%52,5)'ı erkek idi. Katılımcıların %76,4 (n=524)'unde herhangi bir patolojiye rastlanmadı. Refraksiyon kusuru %19,10 (n=131), ambliyopi %2,9 (n= 15), şaşılık %1,75 (n= 12), fizyolojik

Arteriovenous fistulas (AVFs), which have low complication rates and can stay open for a long time, are preferentially used for hemodialysis in patients with end-stage renal disease (ESRD). Arteriovenous fistulas for hemodialysis frequently cause complications such as bleeding, thrombosis, ischemia of extremities, infection, edema, venous hypertension and venous aneurysm. These complications have negative effects on the quality of life and survival. In this report, a dialysis patient having severe edema in the left eye and arm for one year due to thrombosis in the AVF and experiencing a fast regression of edema after closure of the AVF will be presented. The present case emphasizes that thrombosis in the fistula, a frequent complication of AVF in patients with ESRD, can present with rare symptoms like periorbital edema which prevents unilateral vision in addition to its well-known symptoms.