Rational regulation of the interfacial hydrogen-bond (HB) network to facilitate the rate-determining Volmer step involving water dissociation in alkaline hydrogen evolution reaction (HER) has emerged as a promising yet challenging strategy to break the intrinsic kinetic bottleneck. Herein, three zwitterionic COFs decorated with sulfonate, carboxylate, and phosphonate groups were designed and synthesized as interfacial microenvironment regulators to improve the HB network connectivity at the Pt/C electrode-electrolyte interface, leading to significantly accelerated HER kinetics. Specifically, a combination of in situ Raman spectroscopy, molecular dynamics (MD) simulations, and density functional theory (DFT) calculations demonstrates that COF interfacial regulators effectively disrupt the rigid HB network and induce polarization of interfacial water molecules, leading to a diminished interfacial K+ concentration and a markedly increased fraction of free water, which collectively accelerate interfacial mass transport and water dissociation kinetics. As a result, the optimized Pt/C@S-IMR catalyst delivers exceptional HER performance, achieving an overpotential of merely 66 mV at 100 mA cm−2 and a cell voltage of 1.85 V at 1 A cm−2 with a negligible degradation rate over 400-h in anion-exchange membrane water electrolysis (AEMWE). This study not only establishes zwitterionic COFs with different acidic groups as a versatile interfacial engineering strategy to regulate HB connectivity for efficient alkaline HER, but also provides a universal design paradigm for interfacial engineering in electrocatalysis.

The high toxicity of heavy metal ions (HMIs), especially Pb2+ and Cd2+, makes them a serious concern for human health and environmental safety. Therefore, it is crucial to develop sensitive, accurate, and portable methods for HMIs monitoring. Conductive metal-organic frameworks (MOFs) not only possess large surface area and abundant metal active sites but also own high electrical conductivity, greatly expanding their electrochemical applications. Integrating MOFs with covalent organic frameworks (COFs) has been regarded as an effective way to design highly efficient electrocatalyst. In the present work, a hybrid of bismuth-based conductive MOF based on 2,3,6,7,10,11-hexathioltriphenylene (Bi-HHTP) and COF (Bi-HHTP/COF) was produced for the first time in electrochemical quantification of Pb2+ and Cd2+ through differential pulse anodic stripping voltammetry (DPASV). Due to the synergistic effect of Bi-HHTP with excellent electronic conductivity and abundant adsorption sites for Cd2+ and Pb2+ as well as COF with extremely high porosity, good electronic conductivity and high specific surface area, the Bi-HHTP/COF hybrid achieved a boosted electrochemical capability for Cd2+ and Pb2+. In the range of linearity of 2.5-400 mu g/L, this sensor can determine Pb2+ and Cd2+, featuring detection limits of 0.67 and 0.18 mu g/L, respectively. Environment and food samples including milk, lake water, honey and tap water were employed as real samples for the analysis of Pb2+ and Cd2+, and acceptable results of recovery were gained. Meanwhile, the sensor owned outstanding anti-interference properties, stability and reproducibility. This work not only introduces an effective approach for building bismuth-based conductive MOF/COF hybrids but also proves application potential in electrochemical heavy metal ion determination.

Heavy metals, such as Cd2+, are risky to ecosystems and human health, largely because they are poisonous and prone to bioaccumulation. Consequently, it is vital to build a sensing platform that rapidly detects Cd2+ at very low levels. In this work, we introduce an innovative electrochemical sensing platform built upon a flexible laser-induced graphene (LIG) electrode, whose performance is further boosted by incorporating a bimetallic porphyrin MOF (i.e., YbBi-TCPP) produced via a solvothermal method. Benefitting from the orderly pore structure and numerous redox-active centers of YbBi-TCPP as well as the excellent conductivity of LIG, the gained YbBi-TCPP/LIG displayed apparent cooperation, which substantially boosted the sensitivity of the sensing platform. With the conditions set to their optimum, the sensor exhibited a linear detection scope of 5–400 μg/L, a detection limit of 0.43 μg/L, and produced recovery efficiencies that were notably satisfactory (90.2% - 92.9%) in real meat samples including pork, mutton, and chicken. The manuscript introduces a scalable pathway for obtaining bimetallic porphyrin MOF and establishes a corresponding low-expense, high-durability electrochemical sensor for the appraisal of Cd2+.

Rapid and reliable electrochemical sensing of 4-chlorophenol (4-CP) is highly significant for maintaining the security of water resources. To realize this aim, the primary challenge is the construction of sensing interfaces featuring superior electrocatalytic capabilities. In this work, we present a straightforward, single-step pyrolysis strategy for producing graphene nanosheets (GNP) supported CeO2 together with amorphous carbon (CeO2@C/ GNP), which function as a high-performance electrochemical sensor for 4-CP. Demonstrating good catalytic activity, the fabricated sensor featured a wide linear dynamic range from 0.2 to 30 mu M, and a low detection limit (52 nM) for 4-CP. This improved performance can be due to the synergistic action of CeO2@C with GNP, in which CeO2@C/GNP shorten the electron transfer pathway, increase the active reaction zone, and display outstanding electronic conductivity and electrocatalytic oxidation capabilities for 4-CP. The effectiveness of this sensor for 4CP monitoring is clearly reflected by high recovery rates obtained from water samples. Besides, the sensor was characterized by ideal resistance to interferences, excellent reproducibility, and long-term stability. This discovery delivers important guidance toward the synthesis of metal-organic framework (MOF)-derived materials for use in practical environmental monitoring.

Highly electrocatalytic and durable Co-Nx-C frameworks containing carbon nanofibers (CNFs)/carbon nitrides (CNs) are vital materials for rechargeable zinc-air batteries (RZABs). However, the existing Co-Nx-C frameworks experience severe agglomeration during synthesis and limited active site accessibility/mechanical robustness. In this work, a photo-enhanced bifunctional catalyst with a type II p-n heterojunction (g-C3N4-Co@CNT/Co-N4/ C@CNF) is achieved through a combined "electrospinning + calcination + ball milling" approach. The composite integrates graphitic carbon nitride (g-C3N4) nanosheets with dual active Co sites (nanoparticles and Co-N4 single atoms) anchored on conductive carbon nanofibers. This architecture enables efficient charge separation, enhanced light absorption, and accelerated oxygen redox kinetics. DFT calculations reveal that g-C3N4 modulates the electronic structure and lowers the reaction free-energy barriers, leading the d-band center closer to the Fermi level. Under light irradiation, the g-C3N4-Co@CNT/Co-N4/C@CNF exhibits outstanding ORR/OER catalytic performance, with a small overpotential gap of 0.684 V (E1/2 = 0.930 V, Ej:10 = 1.614 V). In practical application: 1) light-enhanced liquid ZABs with g-C3N4-Co@CNT/Co-N4/C@CNF photoactive catalysts manifest a peak power density of 310 mW cm-2 and a long cycle life exceeding 1100 h. 2) Light-enhanced flexible ZABs also can reach a peak power density of 96 mW cm- 2 and tolerate a wide range of bending angles (0 degrees-180 degrees-0 degrees) during harsh operation. This work offers a new platform for designing efficient photo-electrocatalysts and advancing next-generation solar-electrochemical energy conversion systems.

Non-invasive salivary glucose (Glu) monitoring offers a promising alternative for diabetes management, yet its core challenge lies in the design of ultrasensitive sensing materials. In this study, a hollow NiCo PBA nanocage (H-NiCo PBA) was synthesized by selective etching of NiCo PBA nanocube using ammonia, and then a biphasic heterostructure (H-NiCoP/PBA) with intimate interfacial contact was successfully constructed via low-temperature partial phosphidation. XRD, FTIR, and Raman spectroscopy confirmed the coexistence of metal phosphide phases and PBA frames in the composites, and XPS analysis revealed that phosphorus incorporation effectively regulated the electronic environment around the active sites. Based on this, a Glu electrochemical sensor was fabricated based on a flexible laser-induced graphene (LIG) electrode, which owns high electroconductivity and porous framework. Thanks to the synergistic effect between the high electroconductivity of LIG, excellent electrocatalytic activity of H-NiCoP/PBA heterostructure, and the acceleration of charge transport at the heterogeneous interface, the H-NiCoP/PBA/LIG sensor has a linear response range of 1–1988 μM, high sensitivity (4.19 μA·μM−1·cm−2), and a detection limit as low as 0.54 μM for Glu detection, as well as excellent anti-interference, repeatability, and mechanical stability. Integrated with the smartphone, the sensor successfully realizes dynamic non-invasive tracking of human saliva Glu levels throughout the day, with a spiked recovery rate of 98.8%-108.6%, and the postprandial Glu response trend is highly consistent with physiological expectations. This work provides an effective new approach for the development of high-performance non-enzymatic electrochemical sensors and shows good application prospects in the field of non-invasive health monitoring.

Creating high-performance, dependable, and responsive glucose (Glu) sensors is vital for the progress of health monitoring and medical diagnostics. An economical and stable alternative is offered by non-enzymatic electrochemical sensor that use metal-based materials for direct Glu oxidation. Herein, a composite of carbon nanotube (CNT) and FeNi Prussian blue analogs (PBA) was prepared, in which FeNi PBA nanocubes were uniformly linked by CNT to form an interconnected bead-on-a-string network. Then, the FeNi PBA/CNT composite was dropped on an integrated three-electrode system based on laser induced graphene (LIG), forming a novel FeNi PBA/CNT/LIG sensing platform for Glu. The sensor based on FeNi PBA/CNT/LIG could determine Glu from 0.5 μM to 599.5 μM with a high sensitivity of 2.730 μA μM−1 cm−2 and a low detection limit of 0.05 μM. Compared with FeNi PBA/LIG and CNT/LIG controls, the FeNi PBA/CNT/LIG sensor exhibits significantly enhanced performance. The observed improvement can be explained by the exceptional properties of each component. Porous LIG forms an ideal substrate with remarkable conductivity and high surface area, facilitating electron transfer. Meanwhile, FeNi PBA/CNT enriches the composite with plentiful active sites, excellent catalytic capability and good conductivity. Subsequently, a portable detection platform integrating a FeNi PBA/CNT/LIG sensor, a mini electrochemical workstation, and a smartphone was established for the quantitative examination of Glu in food and beverage samples. These results provide a way of developing portable and on-site electrochemical sensors of real-time Glu monitoring.

Sweat glucose (Glu) monitored by a non-enzymatic electrochemical sensing platform can function as a promising alternative for diabetes management, due to its non-invasive nature and great efficiency. Nevertheless, the low level of Glu in sweat has hindered the advancement of present sensors. Herein, we engineered a cyanide (CN) vacancy-defected hollow NiFe Prussian blue analogue (H-NiFe PBA) nanocage anchored with Au nanoparticles (NPs) through an acid etching and electrodeposition process. Integrated with a flexible laser-induced graphene (LIG) electrode array, a novel Au@H-NiFe PBA/LIG sensor was constructed for touch-based electrochemical sensing of Glu in fingertip sweat. The vacancy-defect and hollow structure of H-NiFe PBA endows it with abundant active sites and charge transport channels, while highly dispersed Au NPs and LIG substrate with 3D porous structure ensure rapid electron transfer. Based on this, the Au@H-NiFe PBA/LIG sensor displays outstanding electrocatalytic activity toward Glu oxidation, achieving a wide linear range (1–2332 μM), a satisfactory detection limit (0.67 μM) and sensitivity (3.484 μA μM−1 cm−2), along with good anti-interference capability, response speed, flexibility, stability and repeatability. Moreover, calcium alginate (CA) gels with favorable biocompatibility and swelling properties were utilized for modification, achieving fast touch analysis of Glu in fingertip sweat. This study offers a CN-vacancy engineering strategy for constructing highly efficient electrocatalysts, evolving the advancement of high-performance sensors for noninvasive analysis of Glu in sweat.

The development of high-performance carbon anodes from coal liquefaction pitch for sodium-ion batteries (SIBs) remains challenging due to insufficient functional groups, uncontrollable graphitization, and the lack of precise molecular-level regulation, which collectively lead to inadequate Na+ storage sites, restricted interlayer spacing, and sluggish ion transport kinetics. To address these limitations, we propose a molecular structure-oriented strategy that integrates solvent fractionation, pre-oxidation, and structure-matched cross-linking to precisely tailor the architecture of pitch-derived carbons. The toluene-soluble (TS) fraction of pitch, which is rich in small aromatic cores and abundant aliphatic side chains, is selectively pre-oxidized to introduce carbonyl groups. These groups subsequently undergo esterification with hydroxyl-rich chitin, constructing a three-dimensional cross-linked network via –C(O)–O– linkages. This molecularly designed network imposes spatial confinement, effectively inhibiting graphitic layer rearrangement during pyrolysis and resulting in pseudo-graphitic carbons with expanded interlayer spacing and abundant closed ultramicropores. As an anode for SIBs, the resulting carbon (OTSCC) delivers a high reversible capacity of 318 mAh g−1, an initial Coulombic efficiency of 76.1%, and remarkable cycling stability with 82.5% capacity retention after 500 cycles at a current density of 500 mA g−1. This work underscores the critical role of precursor fraction control and molecular-matched cross-linking in designing advanced carbon materials for energy storage, providing a rational synthesis pathway toward high-performance SIB anodes.

There is a critical need to develop high-performance, easy-to-use glucose (Glu) sensors to support effective diabetes care and monitoring. Featuring high catalytic properties, improved electroconductibility, tunable porosity, and large surface area, conductive metal-organic frameworks (cMOF) (e.g., HHTP-based cMOF) have emerged as attractive platforms for boosting the performance of electrochemical Glu sensors. Laser-induced graphene (LIG) on a polyimide (PI) substrate has attracted considerable research interest in electrochemical sensor, stemming from its excellent conductive properties, flexibility and straightforward fabrication process. Herein, LIG electrode was integrated with NiCo-HHTP, forming a novel NiCo-HHTP/LIG sensor toward Glu. Under optimal conditions, the prepared NiCo-HHTP/LIG sensor demonstrates a low detection limit of 0.12 mu M. The superior electrocatalytic performance of the NiCo-HHTP/LIG sensor is attributed to the bimetallic synergies of NiCo-HHTP and porous structure of LIG, which provides numerous exposed active sites, a high surface area and extraordinary electroconductibility. The sensor's suitability for real-sample analysis was confirmed by successful Glu detection in honey and human sweat, with recoveries calculated to be between 93.8% and 105.2%. This work introduces a viable electrode option to advance the field of non-enzymatic Glu sensing, particularly for applications requiring in-situ and on-site analysis.

BACKGROUND:Accurate, rapid and on-site quantification of glucose (Glu) is crucial for the management of diabetes and its complications as well as food safety monitoring. Electrochemical sensors for non-enzymatic Glu quantification have attracted significant attention due to their ease of miniaturization, straightforward integration, high sensitivity and fast response. However, conventional non-enzymatic sensors still largely rely on large laboratory instruments and rigid electrodes, making it difficult to fully meet the requirements for on-site real-time detection. RESULTS:In this work, we report the detailed design of a portable non-enzymatic sensor combined with a Bluetooth-enabled smartphone and a flexible electrode for on-site detection of Glu. The flexible electrode was based on a three-dimensional porous laser-induced graphene (LIG) supported with nitrogen-doped carbon-encapsulated copper nanoparticles (Cu@NC/LIG), which was prepared through laser irradiation on a Cu-BTC/LIG surface. This rational design combines the three-dimensional conductive network and inherent flexibility of LIG with the high electrocatalytic activity of Cu@NC for Glu oxidation. Results show that the constructed sensor exhibits a wide linear range for Glu detection (1 μM to 8 mM), a low detection limit (0.53 μM), and satisfactory repeatability, stability, flexibility, response speed, and anti-interference capability. Furthermore, the sensor was integrated with a smartphone and successfully applied to detect Glu in complex food and beverages, achieving a satisfactory recovery rate. SIGNIFICANCE AND NOVELTY:This work demonstrates the practical potential of this convenient laser-fabricated, flexible sensor for portable and intelligent on-site detection platforms. The described laser scribing procedure permits the rapid, low-expense generation of high-caliber electrochemical sensors, made more effective through the strategic embedding of customized MOF-originating composites.

The electrocatalytic reduction of carbon dioxide (CO2RR) to valuable products presents a promising solution for addressing global warming and enhancing renewable energy storage. Herein, we construct a novel Ni3ZnC0.7/Ni heterostructure electrocatalyst, using an electrospinning strategy to prepare metal particles uniformly loaded on nitrogen-doped carbon nanofibers (CNFs). The incorporation of zinc (Zn) into nickel (Ni) catalysts optimizes the adsorption of CO2 intermediates, balancing the strong binding affinity of Ni with the comparatively weaker affinity of Zn, which mitigates over-activation. The electron transfer within the Ni3ZnC0.7/Ni@CNFs system facilitates rapid electron transfer to CO2, resulting in great performance with a faradaic efficiency for CO (FECO) of nearly 90% at 0.86 V versus the reversible hydrogen electrode (RHE) and a current density of 17.51 mA cm2 at 1.16 V versus RHE in an H-cell. Furthermore, the catalyst exhibits remarkable stability, maintaining its crystal structure and morphology after 50 h of electrolysis. Moreover, the Ni3ZnC0.7/Ni@CNFs is used in the membrane electrode assembly reactor (MEA), which can achieve a FECO of 91.7% at a cell voltage of 3 V and a current density of 200 mA cm2 at 3.9 V, demonstrating its potential for practical applications in CO2 reduction. (c) 2025 Institute of Process Engineering, Chinese Academy of Sciences. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Electrochemical capacitors show great promise in alternate current (AC) line filtering for modern miniaturized electronics, yet their widespread adoption is significantly hindered by limited voltage windows and slow response. Herein, an aqueous electrochemical capacitor for wide‐voltage and ultrafast‐response filtering is developed using the boron‐doped diamond electrodes that feature both the ultra‐wide potential window of 2.93 V and vertical‐oriented nanoarray architecture. This capacitor exhibits a wide voltage window up to 2.5 V larger than those of reported aqueous filtering capacitors to date and a high‐frequency response capability with a characteristic frequency f 0 = 3338 Hz, as well as a phase angle of −80.4° and a high specific energy density of 365.6 µFV 2 cm −2 at 120 Hz. These superior properties enable effective ripple smoothing of rectified AC signals with complex waveforms, high frequency (60–1000 Hz), and large voltage amplitudes up to 5 V. This work presents an enlightening strategic design of filtering electrochemical capacitors featuring wide voltage windows and high‐frequency response, thereby providing an effective solution to address key challenges in the integration and miniaturization of next‐generation electronic devices.

Low-platinum (low-Pt) alloys are widely regarded as a promising alternative to commercial Pt/C catalysts, owing to their excellent balance of cost reduction and enhanced catalytic performance. However, they have long been hindered by a critical challenge-poor durability-primarily stemming from the dissolution of non-noble metals. Herein, we report a series of high-performance, stable low-Pt high-entropy intermetallic catalysts with the composition Pt(FeCoNi)3-xInx (where x = 0.25, 0.5, 0.75, 1), and systematically elucidate the role of entropy in regulating both the dissolution behavior of non-noble metals and the overall catalytic performance. The optimized high-entropy intermetallic Pt(FeCoNi)2.5In0.5 (PFCNI) exhibited significantly superior stability to its binary counterparts. PFCNI delivered an initial mass activity of 1.04 A mgPt-1, with only a 14.3% loss after 30 000 accelerated durability test (ADT) cycles-outperforming both commercial Pt/C and the binary reference catalysts. When integrated into a membrane electrode assembly (MEA), PFCNI retained 74.1% of its maximum power density after 30 000 accelerated stress test (AST) cycles. In contrast, the MEA based on PtNi3 (a binary counterpart) retained merely 16.8% of its maximum power density even after a shorter duration of 20 000 AST cycles. This study demonstrates that the high-entropy effect remarkably enhances the stability of typical PtM3-type catalysts for the acidic oxygen reduction reaction (ORR), thereby offering a promising strategy for the development of low-Pt catalysts with long-term durability.

Combining silicon nanoparticles (Si NPs) with graphite is considered as a promising strategy to develop commercial anodes for high‐energy lithium-ion batteries (LIBs). Nevertheless, the challenge lies in achieving homogeneous dispersion while ensuring the Si NPs make effective electrical contact within the graphite matrix. Herein, a scalable double-roll milling process is developed to uniformly disperse and embed Si NPs within graphite sheets (GS), yielding the E-Si-GS composite. The mechanical rolling force enables effective interlayer confinement of Si NPs, which are firmly anchored to the GS via van der Waals interactions and amorphous carbon bridging. Meanwhile, the preconstructed internal voids between GS and Si NPs efficiently accommodate the volume expansion of Si NPs and promote electrolyte infiltration. Benefiting from these structural merits, the E-Si-GS anode delivers excellent rate capability and long-term cycling stability, achieving a capacity retention of 89.3% over 800 cycles at 3 C. When matched with a LiFePO4 cathode, the assembled full cell exhibits a high-capacity retention of 95.7% after 100 cycles at 1 C. Furthermore, high-mass-loading testing, pouch cell fabrication, and LED lighting demonstrations further verify the promising practical applicability of the E-Si-GS anode.

Zinc-iodine (Zn-I2) batteries are promising for grid-scale energy storage, yet rapid capacity fade from polyiodide shuttling remains a fundamental challenge. This shuttling arises from the coupled, stepwise iodine reduction pathway (*I2 *I5 *I3 *I), wherein conventional single-site catalysts that accelerate the rate-limiting *I3 reduction inevitably stabilize long-chain *I5, exacerbating capacity fading. Herein, we introduce atom-cluster catalysts (ACCs) with tailored atomic geometries that decouple the adsorption energetics of key intermediates. The ACCs destabilize *I5 chain formation while optimizing *I3 reduction kinetics, thereby redirecting the reaction toward a low-barrier *I2 *I3 *I pathway and suppressing soluble I5- at its source. As a result, Zn1Co ACCs/I2 cathode delivers a high specific capacity of 230.5 mAh g-1 at 6.5 mg cm-2 over 15 000 cycles (2 A g-1). This atomic-scale pathway-engineering strategy resolves the intrinsic trade-off imposed by linear scaling in stepwise conversion reactions and provides a general approach to enabling long-life operation in Zn-I2 batteries and other multi-intermediate electrochemical systems.

It is essential to acquire efficient electrocatalysts to develop ractopamine (RAC) electrochemical sensors. Herein, we report the synthesis of a series of carbon coated NiFe alloy nanostructures (e.g., NiFe@C nanoparticles, nanocubes and nanocages) using NiFe Prussian blue analogue (PBA) as the precursor. The NiFe@C nanocages exhibited the best electrocatalytic performance for RAC sensing. This is attributed to the embedded NiFe alloy nanoparticles that provide abundant active sites, and the unique nanocage structure facilitates electron transfer pathways while offering a high specific surface area. The resulting sensor achieves a low detection limit (LOD) of 54 nM (S/N = 3) within a linear range of 0.2-12 μM. Moreover, the sensor demonstrates good reproducibility, stability, and excellent long-term stability. Practical applicability was confirmed in meat samples, yielding satisfactory recovery rates ranging from 98% to 108%. A feasible strategy was introduced herein for rational design of metal@carbon electrocatalysts.

The development of efficient technologies capable of rapid and selective sensing of toxic hydroquinone (HQ) and catechol (CC) in water systems represents an urgent priority for environmental monitoring. Herein, we established a novel electrochemical sensor for HQ and CC sensing using a structure of FeNi alloyed nanoparticles interconnected by N-doped carbon nanotubes (FeNi@NCNT). This composite was prepared through the pyrolysis of a MOF-on-MOF structure (i.e., FeNi MOF@ZIF-8), in which the formation of CNT was caused by the selfcatalysis of metallic Zn. Synergy between bimetallic nanoparticles and N-dope CNT contributes to enhanced electrical conductivity, greater electrocatalytic activity, and improved sensing capability for HQ and CC, gaining two well-defined and distinguishable peaks. Featuring high selectivity and a wide linear range, the fabricated FeNi@NCNT electrocatalyst also achieves a remarkably low detection limit of 3 nM and 69 nM for HQ and CC, respectively. As a comparison, a recently reported CoP/N,P-C-based electrochemical sensor exhibited LODs of 10 nM and 150 nM for HQ and CC, respectively, demonstrating high improvements in sensitivity with our system. The practical applicability of this method was validated by good recovery in real water sample, highlighting their highly accurate, precise, and robust potential for environmental analysis. This work thus presents a simple method to fabricate FeNi@NCNT with hierarchical structure with exceptional electrocatalytic activity for selective dihydroxybenzene electrochemical sensors.

Reliable and sensitive detection of H2O2 is critical in food safety. Herein, we constructed a novel electrochemical sensor based on laser induced graphene anchored with PtCoCu nanoalloy (PtCoCu/LIG) for H2O2 detection. The PtCoCu/LIG was prepared via a two-step laser direct writing process: LIG was first generated on a polyimide substrate, followed by dip-coating and electrodeposition to obtain Pt/CoCu-ZIF/LIG, then converted into PtCoCu/LIG by a second laser irradiation. Experimental and DFT results reveal that the synergistic effect between PtCoCu and LIG, together with the electronic modulation by Pt, endows the sensor with strong electrocatalytic activity, superior conductivity, and satisfactory sensing performance. Thus, PtCoCu/LIG exhibits a high sensitivity of 0.163 μA μM-1 cm-2, a low detection limit of 0.67 μM, and robust selectivity and stability. The reliability of this method was validated in spiced peanut, milk, vitamin drinks, orange juice, and honey samples, offering a promising detection strategy for food matrices.