Periodically driven quantum many-body systems exhibit a wide variety of exotic nonequilibrium phenomena and provide a promising pathway for quantum applications. A fundamental challenge for stabilizing and harnessing these highly entangled states of matter is system heating by energy absorption from the drive. Here, we propose and demonstrate a disorder-free mechanism, dubbed Fock space prethermalization (FSP), to suppress heating. This mechanism divides the Fock space network into linearly many sparse subnetworks, thereby prolonging the thermalization timescale even for initial states at high energy densities. Using 72 superconducting qubits, we observe an FSP-based time-crystalline order that persists over 120 cycles for generic initial Fock states. Further, we perform finite-size scaling analysis for domain wall (DW) and Fock space dynamics by varying system sizes, which reveals size-independent regimes for FSP-thermalization crossover and links the dynamical behaviors to the eigenstructure of the Floquet unitary. Our Letter establishes FSP as a robust mechanism for breaking ergodicity and paves the way for exploring novel nonequilibrium quantum matter and its applications.

A pivotal task for quantum computing is to speed up the solution of problems that are both classically intractable and practically valuable. Among these, combinatorial optimization problems have attracted tremendous attention due to their broad applicability and natural fitness to Ising Hamiltonians. Here we propose a quantum-sampling strategy, on the basis of which we design an algorithm to accelerate the solution of the ground states of the Ising model, a class of Nondeterministic Polynomial time (NP)-hard problems in combinatorial optimization. The algorithm employs a shallow-circuit quantum-sampling subroutine to navigate the energy landscape. Using up to 104 superconducting qubits, we experimentally demonstrate that this algorithm outputs favorable solutions compared with even a highly optimized classical simulated-annealing algorithm, and we illustrate the path toward quantum speedup based on the time-to-solution metric relative to simulated annealing under serial execution. Our results indicate a promising alternative to classical heuristics for combinatorial optimization, for which quantum advantage may become possible on near-term superconducting quantum processors.

Quantum computers hold the potential to surpass classical computers in solving complex computational problems. The fragility of quantum information and the error-prone nature of quantum operations necessitate the use of quantum error correction codes to achieve fault-tolerant quantum computing. However, most codes that have been demonstrated so far suffer from low encoding efficiency, and their scalability is hindered by prohibitively high resource overheads. Here we use a 32-qubit quantum processor to demonstrate two low-overhead quantum low-density parity-check codes, a distance-4 bivariate bicycle code and a distance-3 punctured bivariate bicycle code. Utilizing a two-dimensional architecture with overlapping long-range couplers connecting the qubits, we demonstrate the simultaneous measurements of all non-local weight-6 stabilizers via the periodic execution of an efficient syndrome extraction circuit. We achieve a logical error rate per logical qubit per cycle of (8.91 ± 0.17)

The topological surface code is a leading candidate for harnessing long-range entanglement to protect logical quantum information against errors, and teleportation of logical states is desirable for robust quantum information processing. Nevertheless, scaling up the surface code in quantum teleportation poses a formidable challenge to experiment. Here on a superconducting quantum processor with 125 qubits, we demonstrate the robust teleportation of topological rotated surface code prepared by a linear-depth unitary circuit, with code distances up to 7. We obtain the teleportation phase diagram by tuning the local entangling gates uniformly across a finite threshold. Furthermore, we show that the entangling threshold can be boosted by coherent qubit rotations that inject magic resources beyond the Clifford regime, restoring the duality symmetry of the topological phase, which serves as a guiding principle to minimize the entanglement resource. Our results shed light on simulating and leveraging topological quantum matter on quantum devices, and pave the way to the ultimate goal of distributed fault tolerant quantum computation.

Fault-tolerant logical operations are fundamental for scalable quantum computation. Here, we report the experimental realization of lattice-surgery operations between a pair of distance-three surface-code logical qubits on a planar superconducting processor. During repeated syndrome extraction cycles, the logical qubits exhibit per-cycle error rates of 0.0365(2) and 0.0282(1), respectively, after leakage events are rejected. By leveraging joint initialization and lattice splitting, we deterministically prepare a logical Bell state, confirming genuine bipartite entanglement via the error-corrected logical state fidelity. We further execute a two-qubit Deutsch-Jozsa algorithm at the logical level to demonstrate algorithmic utility in a fault-tolerant framework. Finally, to achieve universal control, we implement magic-state injection and gate teleportation to realize continuous non-Clifford rotations about the logical X axis. For the logical R_X(π/4) gate, we achieve a logical gate fidelity of 0.943_-9^+10 conditioned on the absence of detected errors. These results establish lattice surgery as a practical and versatile paradigm for logical computation in near-term surface-code architectures, representing a critical milestone toward scalable fault-tolerant quantum advantage in superconducting circuits.

Quantum computers may outperform classical computers on machine learning tasks. Yet, quantum learning systems may suffer from catastrophic forgetting, which is widely believed to be an obstacle to achieving continual learning. Here, we report an experimental demonstration of quantum continual learning on a superconducting processor. In particular, we sequentially train a quantum classifier with three tasks, two about identifying real-life images and one on classifying quantum states, and demonstrate its catastrophic forgetting. To overcome this dilemma, we exploit the elastic weight consolidation strategy and show that the quantum classifier can incrementally retain knowledge across three tasks with an average accuracy exceeding 92.3%. Additionally, for sequential tasks involving quantum-engineered data, we demonstrate that the quantum classifier outperforms a classical classifier with a comparable number of parameters. Our results establish a viable strategy for empowering quantum learning systems with adaptability to sequential tasks.

A long-standing challenge in quantum computing is developing technologies to overcome the inevitable noise in qubits. To enable meaningful applications in the early stages of fault-tolerant quantum computing, devising methods to suppress post-correction logical failures is becoming increasingly crucial. In this work, we propose and experimentally demonstrate the application of zero-noise extrapolation, a practical quantum error mitigation technique, to error correction circuits on superconducting processors. By amplifying the noise on physical qubits, the circuits yield outcomes that exhibit a predictable dependence on noise strength, following a polynomial function determined by the code distance. This property enables the effective application of polynomial extrapolation to mitigate logical errors. Our experiments demonstrate a universal reduction in logical errors across various quantum circuits, including fault-tolerant circuits of repetition and surface codes. We observe a favorable performance in multi-round error correction circuits, indicating that this method remains effective when the circuit depth increases. These results advance the frontier of quantum error suppression technologies, opening a practical way to achieve reliable quantum computing in the early fault-tolerant era.

The spectral form factor (SFF) captures universal spectral fluctuations as signatures of quantum chaos, and has been instrumental in advancing multiple frontiers of physics including the studies of black holes and quantum many-body systems. The measurement of the SFF in many-body systems is however challenging due to the difficulty in resolving level spacings that become exponentially small with increasing system size. Here, we utilize the random measurement toolbox to perform a direct experimental measurement of the SFF, and hence probe the presence or absence of chaos in quantum many-body systems on superconducting quantum processors. For a Floquet chaotic system, we observe signatures of both short- and long-range spectral correlations in the SFF given by the ramp-plateau behavior. Furthermore, for a Hamiltonian system we utilize the SFF to distinguish a quantum many-body chaotic phase and the prethermal many-body localization. We observe the dip-ramp-plateau behavior of random matrix theory in the chaotic phase and contrast the scaling of the plateau time in system size between the many-body chaotic and localized phases. Finally, we probe the eigenstate statistics by measuring a generalization of the SFF, known as the partial SFF, and observe distinct behaviors in the purity of the reduced density matrices in these two phases. This work unveils a new experimental way of extracting the universal signatures of many-body quantum chaos in quantum devices by probing short- and long-range correlations in the energy spectrum and eigenstates.

Background: The widespread use of various video display terminals (VDTs) always had a detrimental impact on ocular health. Prolonged use of smartphones has been one of the leading causes of dry eye (DE) and asthenopia. Therefore, the purpose of this study is to find a simple and effective strategy to combat screen-related DE and asthenopia. Methods: A group of healthy participants aged 18 and above were randomly assigned to three groups and tasked with a 2 h smartphone reading task. After 1 h of usage, each group adopted different methods of rest: no rest (Group A), a 10 min eye-closed rest (Group B), or a 10 min eye-closed joint artificial tears rest (Group C). Ophthalmological examinations and questionnaires were administered to all participants before and after the 2 h reading task. Results: 90 qualified volunteers, including 29 males and 61 females, were randomly assigned to three groups. Group A demonstrated a significant increase in the severity of DE and asthenopia as evidenced by all the evaluated indices. On the other hand, Group C did not exhibit any notable change in DE and asthenopia symptoms, with an improvement in corneal fluorescein staining (CFS) results (P > 0.05) when compared to the pre-reading values. Group B showed a significant increase in ocular surface disease index (OSDI) (P < 0.05) and a decrease in critical flicker frequency (CFF) (P < 0.05). Conclusions: Close-eye rest with artificial tears may be a convenient and effective prevention strategy for screenrelated DE and asthenopia.

Quantum nonlocality describes a stronger form of quantum correlation than that of entanglement. It refutes Einstein’s belief of local realism and is among the most distinctive and enigmatic features of quantum mechanics. It is a crucial resource for achieving quantum advantages in a variety of practical applications, ranging from cryptography and certified random number generation via self-testing to machine learning. Nevertheless, the detection of nonlocality, especially in quantum many-body systems, is notoriously challenging. Here, we report an experimental certification of genuine multipartite Bell-operator correlations, which signal nonlocality in quantum many-body systems, up to 24 qubits with a fully programmable superconducting quantum processor. In particular, we employ energy as a Bell-operator correlation witness and variationally decrease the energy of a many-body system across a hierarchy of thresholds, below which an increasing Bell-operator correlation depth can be certified from experimental data. We variationally prepare the low-energy state of a two-dimensional honeycomb model with 73 qubits and certify its Bell-operator correlations by measuring an energy that surpasses the corresponding classical bound with up to 48 standard deviations. In addition, we variationally prepare a sequence of low-energy states and certify their genuine multipartite Bell-operator correlations up to 24 qubits via energies measured efficiently by parity oscillation and multiple quantum coherence techniques. Our results establish a viable approach for preparing and certifying multipartite Bell-operator correlations, which provide not only a finer benchmark beyond entanglement for quantum devices, but also a valuable guide toward exploiting multipartite Bell correlations in a wide spectrum of practical applications.

Tracking the time evolution of a quantum state allows one to verify the thermalization rate or the propagation speed of correlations in generic quantum systems. Inspired by the energy-time uncertainty principle, bounds have been demonstrated on the maximal speed at which a quantum state can change, resulting in immediate and practical tasks. Based on a programmable superconducting quantum processor, we test the dynamics of various emulated quantum mechanical systems encompassing single- and many-body states. We show that one can test the known quantum speed limits and that modifying a single Hamiltonian parameter allows the observation of the crossover of the different bounds on the dynamics. We also unveil the observation of minimal quantum speed limits in addition to more common maximal ones, i.e., the lowest rate of change of a unitarily evolved quantum state. Our results show a comprehensive experimental characterization of quantum speed limits and enhance the understanding for their subsequent study in engineered non-unitary conditions. Quantum speed limits are fundamental constraints on the speed of quantum state evolution. Here, the authors observe the known maximal quantum speed limits for few and many-body states on a superconducting quantum processor and identify the minimal quantum speed limits, which are less common than maximal ones.

Symmetry-protected topological phases cannot be described by any local order parameter and are beyond the conventional symmetry-breaking paradigm for understanding quantum matter. They are characterized by topological boundary states robust against perturbations that respect the protecting symmetry. In a clean system without disorder, these edge modes typically only occur for the ground states of systems with a bulk energy gap and would not survive at finite temperatures due to mobile thermal excitations. Here, we report the observation of a distinct type of topological edge modes, which are protected by emergent symmetries and persist even up to infinite temperature, with an array of 100 programmable superconducting qubits. In particular, through digital quantum simulation of the dynamics of a one-dimensional disorder-free "cluster" Hamiltonian, we observe robust long-lived topological edge modes over up to 30 cycles at a wide range of temperatures. By monitoring the propagation of thermal excitations, we show that despite the free mobility of these excitations, their interactions with the edge modes are substantially suppressed in the dimerized regime due to an emergent U(1)×U(1) symmetry, resulting in an unusually prolonged lifetime of the topological edge modes even at infinite temperature. In addition, we exploit these topological edge modes as logical qubits and prepare a logical Bell state, which exhibits persistent coherence in the dimerized and off-resonant regime, despite the system being disorder-free and far from its ground state. Our results establish a viable digital simulation approach to experimentally exploring a variety of finite-temperature topological phases and demonstrate a potential route to construct long-lived robust boundary qubits that survive to infinite temperature in disorder-free systems.

Symmetry-protected topological phases1-4 cannot be described by any local order parameter and are beyond the conventional symmetry-breaking model5. They are characterized by topological boundary modes that remain stable under symmetry respecting perturbations1-4,6-8. In clean, gapped systems without disorder, the stability of these edge modes is restricted to the zero-temperature manifold; at finite temperatures, interactions with mobile thermal excitations lead to their decay9-11. Here we report the observation of a distinct type of topological edge mode12-14, which is protected by emergent symmetries and persists across the entire spectrum, in an array of 100 programmable superconducting qubits. Through digital quantum simulation of a one-dimensional disorder-free stabilizer Hamiltonian, we observe robust long-lived topological edge modes over up to 30 cycles for a wide range of initial states. We show that the interaction between these edge modes and bulk excitations can be suppressed by dimerizing the stabilizer strength, leading to an emergent U(1) × U(1) symmetry in the prethermal regime of the system. Furthermore, we exploit these topological edge modes as logical qubits and prepare a logical Bell state, which exhibits persistent coherence, despite the system being disorder-free and at finite temperature. Our results establish a viable digital simulation approach15-18 to experimentally study topological matter at finite temperature and demonstrate a potential route to construct long-lived, robust boundary qubits in disorder-free systems.

Tracking the time evolution of a quantum state allows one to verify the thermalization rate or the propagation speed of correlations in generic quantum systems. Inspired by the energy-time uncertainty principle, bounds have been demonstrated on the maximal speed at which a quantum state can change, resulting in immediate and practical tasks. Based on a programmable superconducting quantum processor, we test the dynamics of various emulated quantum mechanical systems encompassing single- and many-body states. We show that one can test the known quantum speed limits and that modifying a single Hamiltonian parameter allows the observation of the crossover of the different bounds on the dynamics. We also unveil the observation of minimal quantum speed limits in addition to more common maximal ones, i.e., the lowest rate of change of a unitarily evolved quantum state. Our results establish a comprehensive experimental characterization of quantum speed limits and pave the way for their subsequent study in engineered non-unitary conditions.

Greenberger-Horne-Zeilinger (GHZ) states, also known as two-component Schrödinger cats, play vital roles in the foundation of quantum physics and, more attractively, in future quantum technologies such as fault-tolerant quantum computation. Enlargement in size and coherent control of GHZ states are both crucial for harnessing entanglement in advanced computational tasks with practical advantages, which unfortunately pose tremendous challenges as GHZ states are vulnerable to noise. Here we propose a general strategy for creating, preserving, and manipulating large-scale GHZ entanglement, and demonstrate a series of experiments underlined by high-fidelity digital quantum circuits. For initialization, we employ a scalable protocol to create genuinely entangled GHZ states with up to 60 qubits, almost doubling the previous size record. For protection, we take a new perspective on discrete time crystals (DTCs), originally for exploring exotic nonequilibrium quantum matters, and embed a GHZ state into the eigenstates of a tailor-made cat scar DTC to extend its lifetime. For manipulation, we switch the DTC eigenstates with in-situ quantum gates to modify the effectiveness of the GHZ protection. Our findings establish a viable path towards coherent operations on large-scale entanglement, and further highlight superconducting processors as a promising platform to explore nonequilibrium quantum matters and emerging applications.

Recent advancements of quantum technologies have triggered tremendous interest in exploring practical quantum advantage. The simulation of fluid dynamics, a highly challenging problem in classical physics but vital for practical applications, emerges as a potential direction. Here, we report an experiment on the digital simulation of unsteady flows with a superconducting quantum processor. The quantum algorithm is based on the Hamiltonian simulation using the hydrodynamic formulation of the Schr & ouml;dinger equation. With the median fidelities of 99.97% and 99.67% for parallel single- and two-qubit gates respectively, we simulate the dynamics of a two-dimensional (2D) compressible diverging flow and a 2D decaying vortex with ten qubits. Note that the former case is an inviscid potential flow, and the latter one is an artificial vortical flow with an external body force. The experimental results well capture the temporal evolution of averaged density and momentum profiles, and qualitatively reproduce spatial flow fields with moderate noises. This work demonstrates the potential of quantum computing in simulating more complex flows, such as turbulence, for practical applications. Fluid dynamics simulation, a complex challenge in classical physics, is relevant for real-world applications and highlights the potential of quantum computing. The authors report an experiment for the digital simulation of unsteady flows on a superconducting quantum processor, and show that the results effectively capture the evolution of flow fields.

Purpose To evaluate the clinical characteristics and viral Colonization of corneas donated by volunteers with coronavirus disease 2019 (COVID-19) before and after corneal transplantation.Methods We retrospectively compared the characteristics and clinical outcomes of patients who received corneas from donors with and without a history of COVID-19 after corneal transplantation. Reverse transcription-polymerase chain reaction (RT-PCR) was performed to evaluate the expression of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA on ocular surfaces in corneal preservation solutions as well as the recipients’ tears. Immunofluorescence was also performed to evaluate the expression of viral spike proteins in the corneas. Intraocular pressure (IOP) measurement, optical coherence tomography (OCT), and slit-lamp inspection at each follow-up examination were performed to assess the surgical efficacy.Results The RT-PCR results of eye surface swabs before corneal extraction, the corneal preservation solutions before transplantation as well as the recipients’ tears were negative, thereby indicating the suitability for transplantation. No significant differences in IOP measurements, OCT findings, or in the incidence of post transplantation complications were observed between donors with and without COVID-19.Conclusions Corneal transplantation using corneas from COVID-19 infected donors does not alter clinical outcomes when compared to controls receiving corneas from non-infected donors.

Bell nonlocality is an intrinsic feature of quantum mechanics, which can be certified via the violation of Bell inequalities. It is therefore a fundamental question to certify Bell nonlocality from experimental data. Here, we present an optimization scheme to improve nonlocality certification by exploring flexible mappings between Bell inequalities and Hamiltonians corresponding to the Bell operators. We show that several Hamiltonian models can be mapped to new inequalities with improved classical bounds than the original one, enabling a more robust detection of nonlocality. From the other direction, we investigate the mapping from fixed Bell inequalities to Hamiltonians, aiming to maximize quantum violations while considering experimental imperfections. As a practical demonstration, we apply this method to an XXZ-like honeycomb-lattice model utilizing over 70 superconducting qubits. The successful application of this technique, as well as combining the two directions to form an optimization loop, may open new avenues for developing more practical and noise-resilient nonlocality certification techniques and enable broader experimental explorations.

Medical education is primarily based on practical schooling and the accumulation of experience and skills, which is important for the growth and development of young ophthalmic surgeons. However, present learning and refresher methods are constrained by several factors. Nevertheless, virtual reality (VR) technology has considerably contributed to medical training worldwide, providing convenient and practical auxiliary value for the selection of students' sub-majors. Moreover, it offers previously inaccessible surgical step training, scenario simulations, and immersive evaluation exams. This paper outlines the current applications of VR immersive teaching methods for ophthalmic surgery interns.

Non-Abelian topological orders offer an intriguing path towards fault-tolerant quantum computation, where information can be encoded and manipulated in a topologically protected manner immune to arbitrary local noises and perturbations. However, realizing non-Abelian topologically ordered states is notoriously challenging in both condensed matter and programmable quantum systems, and it was not until recently that signatures of non-Abelian statistics were observed through digital quantum simulation approaches. Despite these exciting progresses, none of them has demonstrated the appropriate type of topological orders and associated non-Abelian anyons whose braidings alone support universal quantum computation. Here, we report the realization of non-Abelian topologically ordered states of the Fibonacci string-net model and demonstrate braidings of Fibonacci anyons featuring universal computational power, with a superconducting quantum processor. We exploit efficient quantum circuits to prepare the desired states and verify their nontrivial topological nature by measuring the topological entanglement entropy. In addition, we create two pairs of Fibonacci anyons and demonstrate their fusion rule and non-Abelian braiding statistics by applying unitary gates on the underlying physical qubits. Our results establish a versatile digital approach to exploring exotic non-Abelian topological states and their associated braiding statistics with current noisy intermediate-scale quantum processors.