One Health is an integrated, unifying approach that aims to sustainably balance and optimize the health of people, animals and ecosystems. Observing the organizational format of the Group on Earth Observations (GEO) Health Community of Practice, the One Health Research Institute was created by Universidad Tecnológica Centroamericana in April 2024. This letter presents the first year of experience of a center that could represent a model research institution in the Americas region.

Since the detonation of the first atomic bomb during World War II, geopolitical issues and armed conflicts have reminded us of the threat posed by nuclear weapons in the short, medium, and long term. The potential consequences include millions of deaths and severe injuries from blast, heat, and acute ionizing radiation. Whatever the country, in the post-acute stage of a nuclear attack, the first challenge for health and rescue personnel will be gaining access to affected populations amidst destroyed infrastructure, hazardous radioactivity, and limited health facilities and medical supplies. Subsequently, the focus will shift to providing timely and appropriate treatment for survivors, addressing environmental damage, and combating malnutrition. Beyond the immediate human toll, the destruction of city infrastructure and the loss of centuries of cultural heritage are also at stake. Governments and health systems must prepare for these scenarios, although any medical or mitigation response may prove inadequate to halt the devastating impact of a failed disarmament or nuclear non-proliferation treaty. Scientists should raise awareness about the dire consequences of nuclear warfare and the realities of a post-nuclear era.

Juvenile myoclonic epilepsy (JME) is the most common of the generalized genetic epilepsies, with multiple causal and susceptibility genes; however, its etiopathogenesis is mainly unknown. The toxic effects caused by xenobiotics in cells occur during their metabolic transformation, mainly by enzymes belonging to cytochrome P450. The elimination of these compounds by transporters of the ABC type protects the central nervous system, but their accumulation causes neuronal damage, resulting in neurological diseases. The present study has sought the association between single nucleotide genetic variants of the CYP2C9, CYP2C19, and ABCB1 genes and the development of JME in patients compared to healthy controls. The CC1236 and GG2677 genotypes of ABCB1 in women; allele G 2677, genotypes GG 2677 and CC 3435 in men; the CYP2C19*2A allele, and the CYP2C19*3G/A genotype in both sexes were found to be risk factors for JME. Furthermore, carriers of the TTGGCC genotype combination of the ABCB1 gene (1236/2677/3435) have a 10.5 times higher risk of developing JME than non-carriers. Using the STRING database, we found an interaction between the proteins encoded by these genes and other possible proteins. These findings indicate that the CYP450 system and ABC transporters could interact with other genes in the JME.

Engineering played a fundamental role during the pandemic, helping to develop new technology to diagnose and trace cases, as well as to improve digital health in many aspects. This work aims to make visible the contributions of Honduran women in engineering by analyzing scientific publications in journals indexed in local or international databases. A descriptive crosssectional study was carried out with a bibliometric approach to characterize the scientific production on COVID-19 in Honduras in relation to engineering. The results showed a greater predominance of women in publications in non-Scopus journals, suggesting fewer publication opportunities or capacities. The publications found were headed by women in 36.8% of cases, but due to the nature of data, academic degrees were not available, and it is not clear how many were engineers or women studying engineering. It is recommended to encourage women engineers or those who are in the final stages of undergraduate studies or postgraduate courses to seek to publish in indexed journals and alike, to join professional engineering organizations such as IEEE, ACM, ASME among other, in order to increase their scientific networks and leadership.

Before the advent of diagnostic criteria for multiple sclerosis (MS), it was reported that the prevalence of MS in Mexico was "one of the lowest in the world" (1.6/100,000).(1) The notion that MS was a rare neurologic disease among those living in the tropics of the Americas and Southern latitudes was widely accepted. The geopolitical boundaries of the region identified as Latin America (LA) extend from the southern border of United States with Mexico (32° North latitude) to the Argentinian and Chilean Patagonia in South America (56° South latitude). The largest Spanish-speaking island countries in the Caribbean-Cuba, Dominican Republic, and Puerto Rico-are also traditionally considered part of LA. The continental mass includes 17 countries with a population of more than 550 million. Due to centuries of racial intermixing, it is a heterogeneous and genetically complex population. The blended cultures of native Amerindians with white Caucasian Europeans and black Africans has resulted in the predominant ethnic Latin American Mestizo. The influence of African genetics is notable in many areas of the subcontinent and the Caribbean. A common observation across LA is the absence of identification of MS in non-mixed Amerindians(2); the reason for this phenomenon is unclear.

Introducción: El rol de la mujer en el área científica ha crecido con el paso de los años, pero aún persiste una gran brecha de género en ciencia. Para conocer y manejar esa brecha, es necesario hacer un mapeo de la situación de las mujeres investigadoras en Honduras. Objetivo: Describir la participación y contribuciones de las investigadoras hondureñas en la producción científica nacional según su perfil en Google Académico. Metodología: Se usó Power BI para analizar las variables sexo, institución, índice H, número de citaciones, número de publicaciones, año de la primera publicación, y áreas de investigación registradas en su perfil, utilizando la versión 2 del Ranking de Investigadores Hondureños según su Perfil de Google Académico disponible en https://bit.ly/38s6YuT, el cual es un registro depurado. Resultados: El 35% de todos los perfiles eran de mujeres, 41% vinculadas a las ciencias médicas y de la salud y en su mayoría (92%), afiliadas a universidades. Pese al creciente número de mujeres investigadoras registradas en Google Académico, el crecimiento no es simétrico respecto a los hombres. Solamente el 3.1% de las investigadoras tenía un índice H que supera los dos dígitos. Conclusión: A pesar de los avances, se mantiene la inequidad de género entre investigadores hondureños según la data de Google Académico. Se requiere de políticas públicas e institucionales, para corregir esa brecha.

Dear Editor, Dahl et al., 2022Dahl V Tiberi S Goletti D Wejse C. Armed conflict and human displacement may lead to an increase in the burden of tuberculosis in Europe.Int J Infect Dis. 2022; S1201–-9712: 00180-00181https://doi.org/10.1016/j.ijid.2022.03.040Abstract Full Text Full Text PDF Scopus (3) Google Scholar recently warned in this journal that armed conflict and human displacement by the Russia-Ukraine conflict may increase the burden of tuberculosis in Europe, but there could be more public health problems ahead. Since last 2 years, the COVID-19 pandemic has been an important catalyst for international collaboration on public health (Jit et al., 2021Jit M Ananthakrishnan A McKee M Wouters OJ Beutels P Teerawattananon Y. Multi-country collaboration in responding to global infectious disease threats: lessons for Europe from the COVID-19 pandemic.Lancet Reg Health Eur. 2021; 9100221https://doi.org/10.1016/j.lanepe.2021.100221Abstract Full Text Full Text PDF PubMed Scopus (3) Google Scholar). This collaboration has not been error-free, especially in relation to an equitable distribution of diagnostic tests, treatments, and vaccines between high-income and low-middle-income countries (Javed and Chattu, 2020Javed S Chattu VK. Strengthening the COVID-19 pandemic response, global leadership, and international cooperation through global health diplomacy.Health Promot Perspect. 2020; 10 (doi: 10.34172%2Fhpp.2020.48): 300-305Crossref PubMed Scopus (20) Google Scholar). The pandemic has been, at least temporarily, a kind of freezer of major war conflicts worldwide owing to the joint efforts to mitigate its impact. A better understanding of the virus, growing herd immunity produced by COVID-19 vaccines and/or previous infection (Randolph and Barreiro, 2020Randolph HE Barreiro LB. Herd immunity: understanding COVID-19.Immunity. 2020; 52: 737-741https://doi.org/10.1016/j.immuni.2020.04.012Abstract Full Text Full Text PDF PubMed Scopus (481) Google Scholar; Radbruch and Chang, 2021Radbruch A Chang HD. A long-term perspective on immunity to COVID.Nature. 2021; 595: 359-360https://doi.org/10.1038/d41586-021-01557-zCrossref PubMed Scopus (20) Google Scholar), and the transition to less lethal variants (Petersen et al., 2022Petersen E Ntoumi F Hui DS et al.Emergence of new SARS-CoV-2 Variant of Concern Omicron (B.1.1.529) - highlights Africa's research capabilities, but exposes major knowledge gaps, inequities of vaccine distribution, inadequacies in global COVID-19 response and control efforts.Int J Infect Dis. 2022; 114: 268-272https://doi.org/10.1016/j.ijid.2021.11.040Abstract Full Text Full Text PDF PubMed Scopus (60) Google Scholar) have coincided with the beginning of a warfare in East Europe. The immediate consequences for Ukraine and surrounding regions are COVID-19 surges, unattended chronic diseases, emerging infections and lower vaccination rates, including anti-COVID-19 vaccination. The risk of an escalation is latent and consequences are unimaginable if nuclear weapons are used. All simulators of a nuclear war conclude in the inevitable figure of millions of deaths and an incalculable number of people affected by radiation (Nuclear Princeton 2019Nuclear Princeton, Princeton Science and Global Security Nuclear War Simulation https://nuclearprinceton.princeton.edu/news/princeton-science-and-global-security-nuclear-war-simulation, 2019 (accessed 22 March 2022).Google Scholar). We already know about the immediate- and long-term aftermath of the Chernobyl disaster and the Hiroshima and Nagasaki nuclear bombings in World War II (Douple et al., 2011Douple EB Mabuchi K Cullings HM Preston DL Kodama K Shimizu Y Fujiwara S Shore RE. Long-term radiation-related health effects in a unique human population: lessons learned from the atomic bomb survivors of Hiroshima and Nagasaki.Disaster Med Public Health Prep. 2011; 5 (Suppldoi: 10.1001%2Fdmp.2011.21): S122-S133Crossref PubMed Scopus (93) Google Scholar). Another threat is the use of biologic and chemical weapons that disseminate biologic agents or toxins to cause harm, disease, and death of humans or animals and harm the environment (Jansen et al., 2014Jansen HJ Breeveld FJ Stijnis C Grobusch MP. Biological warfare, bioterrorism, and biocrime.Clin Microbiol Infect. 2014; 20: 488-496https://doi.org/10.1111/1469-0691.12699Abstract Full Text Full Text PDF PubMed Scopus (81) Google Scholar; Ekzayez et al., 2020Ekzayez A Flecknoe MD Lillywhite L Patel P Papamichail A Elbahtimy H. Chemical weapons and public health: assessing impact and responses.J Public Health (Oxf). 2020; 42: e334-e342https://doi.org/10.1093/pubmed/fdz145Crossref PubMed Scopus (4) Google Scholar). In no way can this type of warfare be local or easy to contain. The global scientific community must warn the world leaders about the abyss into which humanity can fall if consensus is not reached in a timely manner to avoid self-destruction. After the use of nuclear weapons, there will be no winners among survivors. The health systems, especially in the countries most affected by radiation, will have to deal with its short-, medium-, and long-term effects on the population. It is time that states directly or indirectly affected by the Ukraine and Russia conflict cooperate bilaterally or multilaterally to stop the ongoing war. Universidad Tecnológica Centroamericana, Honduras. Not applicable CR and RMD developed the concept, reviewed the literature, and wrote the manuscript. All authors declare no competing interest related to this paper.

Background: Inflammatory markers are pivotal for the diagnosis of coronavirus disease 2019 (COVID-19) and sepsis. This study compared markers between hospitalised patients with COVID-19 and those with bacterial sepsis. Methods: This retrospective single-centre cohort study included 50 patients with COVID-19 clinical stages II and III and 24 patients with bacterial sepsis. Both groups were treated according to the country's official standards. Leukocytes, C-reactive protein (CRP), ferritin, and D-dimer were registered at the time of patient's admission and 24, 48, and 72 h after initiating intrahospital treatment. Results: Upon admission, marker levels were high, with a significant decrease at 72 h after antibiotic therapy in the sepsis group. The leukocyte count was higher in deceased patients with sepsis. The mean ferritin levels were 1105 mcg/dl for COVID-19 and 525 mcg/dL for sepsis. Higher ferritin levels in COVID-19 (P = 0.001) seemed to be a predictor of higher mortality. Upon admission, the median D-dimer level was 0.68 mg/L for COVID-19 and 3 mg/L for patients with sepsis, whether recovered or deceased. As D-dimer, procalcitonin levels were higher in patients with sepsis (P = 0.001). CRP levels were equally elevated in both entities but higher in deceased patients with COVID-19. Conclusion: Ferritin was the main inflammatory marker for COVID-19, and leukocytes, procalcitonin, and D-dimer were the main markers of sepsis. Markers that were most affected in deceased patients were CRP for COVID-19 and leukocyte for sepsis. The therapeutic implications of these differences require further study.

Proper territorial data management is critical for territorial planning projects, research, innovation, and the appropriate follow-up to act for the well-being of populations. A multidisciplinary team of professionals established a pilot project named Cortes Data Hub (Centro de Datos de Cortés). It presents several dashboards that show official statistics on the energy sector, mapping the region’s energy demand, data on COVID-19 cases and vaccination rates by municipality or department, and a project using Google Earth that combines post-Eta and Iota observations and a social media campaign for disaster awareness and for the promotion of activities to develop tourism in the San Manuel Municipality. This pilot project shows the importance to observe and monitor various key environmental, health, and socioeconomic data. This will help improve initiatives for local development, disaster prevention and control, and the promotion of the One Health approach. The challenges to overcome are the quality and timing of data. Training more academics, government teams, and decision-makers in the use of new tools for data integration with earth observations are important for the Cortés department’s development.

International travel is rebounding as coronavirus disease 2019 (COVID-19) vaccinations continue and more countries are opting for ‘living with COVID’ in the hopes of moving from a pandemic footing toward an endemic one. Such travel remains far from risk-free, however, given the existence of asymptomatic carriers and the emergence of new severe acute respiratory syndrome coronavirus 2 variants. To protect their residents, most countries have instituted policies requiring incoming travelers to be fully vaccinated according to their own policies and to show proof of a negative COVID test [1,2]. This has raised new challenges for everyone who wants to travel internationally, especially for those who have received vaccines not yet approved by the World Health Organization (WHO) and other regulatory agencies like the United States Food and Drug Administration and the European Medicines Agency. Residents of many low-tomiddle income countries do not have access to some vaccines approved by these entities. This generates clear inequalities in international travel policies around the world. The case of individuals vaccinated with Gam-COVID-Vac is an example. On February 2, 2021, the first study on the vaccine, produced by the Gamaleya Institute in Russia, reported on the safety and efficacy of this rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 jab (Gam-COVID-Vac or Sputnik V). The efficacy was 91.6%, similar to the mRNA vaccines BNT162b2 (BNT, Pfizer; Pfizer, New York, NY, USA) and mRNA-1273 (Moderna, Cambridge, MA, USA), and superior to the adenoviral vaccines ChAdOx1 nCoV-19 (AZD1222; AstraZeneca, Cambridge, UK) and Ad.26. COV2 (J&J/Janssen; Johnson & Johnson, New Brunswick, NJ, USA) [3,4]. Many countries as well as the WHO, have not approved vaccination with Gam-COVID-Vac waiting for reliable independent validation of its efficacy [5]. Yet, given the scarcity of WHO-approved vaccines, this vaccine has been used in at least 75 countries in Asia, Africa, and Latin America [6]. Consequently, many persons vaccinated with the Gam-COVID-Vac from these countries have experienced restrictions in their international movements. Beginning in November 2021, all travelers to the United States were required to show proof of being fully vaccinated as well as a negative COVID-19 test. Only WHO-approved vaccines were accepted, leaving persons who have had the Gam-COVID-Vac not considered fully vaccinated [7,8] and consequently unable to enter the United States. This complex situation also applies to those who got other COVID vaccines not approved by the WHO, including Cansino (CanSinoBIO, Tianjin, China), Novavax (produced in India), EpiVacCorona (VECTOR Center of Virology, Koltsovo, Russia), Abdala (Center © Korean Vaccine Society. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/ by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. K O R E A N V A C C I N E S O C I E T Y

Resumen-El norte de Honduras experimentó un alto impacto al sufrir el paso de los huracanes Eta e Iota durante un pico de COVID-19 en el año 2020. Se realizó encuestas de campo para evaluar las experiencias y percepciones de los pobladores de la ciudad de San Pedro Sula, como parte del proyecto "Centro de Datos de Observaciones de la Tierra" de la UNITEC. Se usó ArcGIS Survey y PowerBI para procesar y visualizar las respuestas de 1,428 encuestados (ver Cortés Data Hub). Los principales impactos fueron pérdida de empleo, muerte de familiares, migración, daños a viviendas y cierre de empresas. El 48% de encuestados reportó la intención de iniciar algún emprendimiento, especialmente relacionados a apertura de tiendas de varios tipos, venta de insumos, tecnología y servicios de varios tipos. El 22% de los entrevistados manifestó la intención de emigrar. El proveer opciones para emprendimientos exitosos, es una urgencia por parte del estado y del sector privado. Las instituciones académicas también deben innovar para responder a

Introduction: Azithromycin combined with hydroxychloroquine or chloroquine has been used as treatment for SARS-CoV-2, but prolongation of QTc interval and malignant arrhythmias have been reported as adverse events. The occurrence of these abnormalities in Honduran patients is unknown. Aim of the study: To determine the prevalence of cardiac arrhythmias and prolongation of the QTc interval in hospitalized COVID-19 patients treated with hydroxychloroquine plus azithromycin at Hospital General del Sur at Choluteca, Honduras. Methods: 24-hour electrocardiograms were performed in 21 patients over 18 years of age with COVID-19 stage II or III receiving treatment for seven days. Diagnosis was done by RT-PCR and/or with other accepted combined criteria. Analysis were done for QTc interval, supraventricular or ventricular arrhythmias, and heart rate variability. Results: Overall, 67% of patients were men and 33% had comorbidities (diabetes mellitus, high blood pressure and heart failure). Patients were hospitalized for at least 16 days. Median QTc interval was 410 milliseconds, median minimum heart rate 56 beats per minute, and median maximum heart rate 126 beats/minute. Four patients (19%) presented ventricular arrhythmias (<30 premature ventricular contractions in one hour, bigeminy, and a run of non-sustained monomorphic ventricular tachycardia). All patients showed QTc intervals less than 490 milliseconds. Conclusions: Frequency of ventricular arrhythmias during monitoring was in the lower ranges compared to similar studies. No prolongation of QTc interval was observed.

Vaccine-induced immune thrombotic thrombocytopenia (VITT) is an extremely rare complication associated with the adenovirus-vectored coronavirus disease 2019 (CO-VID-19) ChAdOx1 nCoV-19 (AZD1222) vaccine.It is characterized by venous thrombosis, mainly cerebral venous sinus thrombosis, moderate to severe thrombocytopenia, and rarely, thrombosis in cerebral arteries.This syndrome is similar to the heparin-induced thrombocytopenia and presents mostly among women aged 18-55 years, without previous exposure to heparin, usually 5 to 20 days after vaccination.However, cases have been reported in men and older adults [1][2][3][4].Unlike COVID-19, this adverse effect might not represent a public health problem in itself, but it is already causing vaccine hesitancy in population groups susceptible to severe COVID-19, and poses a challenge in low resource settings [5].The first case reports showed evidence that VITT has a mortality around 40% [1-3].So far, cases have been reported and treated in hospitals of highly developed countries with first-rate health systems that facilitate early detection and treatment of this severe adverse event.VITT is confirmed by using PF4-dependent enzyme-linked immunosorbent assay (ELISA) assay, which allows the differential diagnosis from other causes of thrombosis in patients with a history of ChAdOx1 nCoV-19 vaccination in previous days.However, it is likely that a large number of hospitals in many low-middle income countries do not have approved PF4-dependent ELISA assays for accurate diagnosis, nor immunoglobulins, glucocorticoids, and non-heparin anticoagulants needed for the treatment of this condition [1][2][3][4].In times of this COVID-19 pandemic and precision medicine, problems and solutions should be considered global.Policies related to COVID-19 need to be addressed considering varied public health and socioeconomic contexts.The ChAdOx1 nCoV-19 vaccine is one of the most used vaccines in low-middle income countries, where special testing to confirm VITT is not widely available.Therefore, real figures are unknown, and underreporting of this adverse effect should be considered.Patient information, government, and hospital preparedness in these countries are needed to diagnose and manage VITT adequately, and to reduce morbidity and mortality from this complication.These strategies will have a positive impact on public acceptance and adherence to COVID vaccination.

Justificación: la webometría se ha usado para medir la actividad y visibilidad científica en los países. Objetivo: construir un ranking de investigadores hondureños según las citaciones en sus perfiles de Google Académico y su afiliación institucional. Metodología: se realizó una búsqueda sobre publicaciones científicas de investigadores e instituciones académicas e independientes de Honduras registradas en Google Académico. La información se organizó en Microsoft Excel y se analizó con la herramienta Tableau, con la cual también se creó un tablero interactivo para acceso público, mostrando frecuencias, porcentajes y promedios de las citaciones de los investigadores y otros criterios. Resultados: el 72% (110/151) de los investigadores con perfiles disponibles eran hombres; la Universidad Nacional Autónoma de Honduras lideró el porcentaje de investigadores con el 55.6%; (84/151), seguida por la Universidad Tecnológica Centroamericana con el 13.9%; (21/151) y la Escuela Agrícola Panamericana con el 12.6%; (19/151). Los investigadores de la Escuela Agrícola Panamericana mostraron el mayor promedio de citaciones por investigador (390), seguida por los investigadores de la Universidad Nacional Autónoma de Honduras (179) y los de la Universidad Tecnológica Centroamericana (177). Los investigadores en los primeros 20 lugares, clasificados con el índice H, también pertenecían a estas universidades. Las disciplinas más frecuentemente reportadas por los investigadores fueron las ciencias sociales (27.2%), de la salud (22.53%), agrícolas (9.32%) y las naturales (8.6%). Conclusiones: el mayor número de investigadores con perfiles en Google Académico pertenecían a la Universidad Nacional Autónoma de Honduras, pero los investigadores de dos universidades privadas tuvieron un promedio de citación por autor casi igual o mayor a los de dicha institución. El tablero público de ranking de investigadores hondureños https://tabsoft.co/3wK3vym, puede orientar estrategias de visibilidad de los científicos del país.

A recently published article of this journal stated that informatics solutions can guide better public health decision-making during the COVID 19 (Coronavirus Disease 2019) pandemic. Honduras is a country facing the COVID-19 pandemic with a weak health surveillance system while also fighting a dengue epidemic and the aftermath of two hurricanes that struck its territory in November 2020. In response, we as academics started a COVID-19 and Dengue Observatory combining several technological platforms and developing multidisciplinary research to help the country navigate the crisis. Mapping the pandemic and the natural disasters showed us that technology can be applied toward epidemiology to benefit communities in a time of need by quickly building a basic digital health surveillance system for Honduras.

Introduction: Azithromycin combined with hydroxychloroquine or chloroquine has been used as treatment for SARS-CoV-2, but prolongation of QTc interval and malignant arrhythmias have been reported as adverse events. The occurrence of these abnormalities in Honduran patients is unknown. Aim of the study: To determine the prevalence of cardiac arrhythmias and prolongation of the QTc interval in hospitalized COVID-19 patients treated with hydroxychloroquine plus azithromycin at Hospital General del Sur at Choluteca, Honduras. Methods: 24-hour electrocardiograms were performed in 21 patients over 18 years of age with COVID-19 stage II or III receiving treatment for seven days. Diagnosis was done by RT_PCR and/or with other accepted combined criteria. Analyses were done for QTc interval, supraventricular or ventricular arrhythmias, and heart rate variability. Results: Overall, 67% of patients were men and 33% had comorbidities (diabetes mellitus, high blood pressure and heart failure). Patients were hospitalized for at least 16 days. Median QTc interval was 410 milliseconds, median minimum heart rate 56 beats per minute, and median maximum heart rate 126 beats/minute. Four patients (19%) presented ventricular arrhythmias (<30 premature ventricular contractions in one hour, bigeminy, and a run of non-sustained monomorphic ventricular tachycardia). All patients showed QTc intervals less than 490 milliseconds. Conclusions: Frequency of ventricular arrhythmias during monitoring was in the lower ranges compared to similar studies. No prolongation of QTc interval was observed.

Introducción. En julio 2021, había alrededor de 40,000 hondureños pendientes de la segunda dosis de la vacuna anticovid Sputnik V, por lo que se propuso ofrecerles cruce de vacuna. El grupo también incluía al personal de medios de comunicación. Este sondeo de opinión evaluó la aceptación y otras percepciones sobre el cruce en este grupo. Métodos. Se realizó una encuesta rápida al personal de medios de comunicación y a población general especialmente adultos mayores en espera de la segunda dosis. Resultados. Se obtuvo respuestas de 146 personas entre 21 a 95 años; 7 (4.8%) ya se habían aplicado la segunda dosis y 5 (3.4%) ya había hecho algún cruce con otra vacuna. Del resto (134 personas), 35.8% (n=48) era personal de medios de comunicación, especialmente reporteros o presentadores en radio y televisión. El 67.9% de todos los participantes manifestó preocupación, pero prefería esperar la llegada de la misma marca de vacuna. El 29.8% opinó que las vacunas anticovid se pueden combinar, pero solamente 14.9% estaba dispuesto a aceptar un cruce personalmente. El 79.1% afirmó saber poco o nada de las bases científicas sobre dichos cruces de vacunas, sin diferencias entre periodistas y no periodistas. La mitad dijo mantener una bioseguridad en rango bueno y la otra mitad en rango excelente. Conclusión. Se encontró poca aceptación al cruce de vacunas, especialmente si se tratara de hacerlo personalmente. Se evidenció la necesidad de más información científica sobre el tema, especialmente entre el personal de medios de comunicación.